Evolocumab reduces cardiovascular events in diabetes without known atherosclerosis
Evolocumab cuts heart events in high-risk diabetes patients
This prespecified subgroup analysis of a phase 3 RCT evaluated evolocumab added to statin therapy in 3655 high-risk patients with type 2 dia…
Adding evolocumab to statins reduced heart attacks and strokes by about 30% in high-risk diabetes patients without known heart disease.
Meta-analysis finds no significant association between statin use and sarcopenia in older adults
Large review finds no clear link between statin use and muscle loss in older adults
A systematic review and meta-analysis of 9,080 older adults from European and Asian populations found no statistically significant associati…
A large review of over 9,000 older adults found no clear link between taking statins and losing muscle mass or strength.
Inclisiran plus usual care improves LDL-C goal attainment after acute coronary syndrome
Inclisiran helps heart patients hit cholesterol goals fast
This phase 3b open-label RCT in 400 patients discharged after acute coronary syndrome found that adding inclisiran to usual care led to sign…
A new shot helped 3 in 4 recent heart attack patients reach LDL targets within 90 days, far more than usual care alone.
Guideline on cost-effectiveness of add-on ezetimibe for statin-intolerant acute coronary syndrome patients in Thailand
Add-on ezetimibe may be cost-effective for statin-intolerant patients in Thailand
This cost-utility analysis evaluates add-on ezetimibe versus moderate-intensity statin alone for acute coronary syndrome patients in Thailan…
Adding ezetimibe to moderate-intensity statin therapy appears cost-effective for patients in Thailand who cannot tolerate high-intensity sta…
Pre-admission statin use linked to better 30-day outcomes after aneurysmal SAH
Pre-admission statin use linked to better 30-day outcomes in brain bleed patients
This observational study of 1,431 patients with aneurysmal subarachnoid hemorrhage found that pre-admission statin use was associated with a…
Using statins before a brain bleed may improve early recovery chances, but benefits did not last to 90 days in this real-world study.
CABG linked to higher impaired cognition risk in older CAD patients with APO genotype variation
Heart Surgery Tied to Memory Issues in Some Patients
This cohort study of older adults with coronary artery disease found that coronary artery bypass grafting was associated with a higher risk …
Heart bypass surgery may raise memory problem risks in older adults, especially those carrying a specific gene type linked to brain health.