N/A N=4,231 Circulation Improving Resuscitation Care (CIRC)
Cardiac Arrest · Cardiopulmonary Resuscitation
Primary: Hospital Discharge — 196; 233 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=15 ECPR for Refractory Out-Of-Hospital Cardiac Arrest
Cardiac Arrest · Heart Arrest · Sudden Cardiac Arrest
Primary: Emergency Department Arrivals Under 30 Minutes — 5 Participants
N/A N=298 Three Different Cardiopulmonary Resuscitation (CPR) Training Methods
Cardiopulmonary Resuscitation
Primary: CPR Depth — 43.7; 42.2; 35.3 millimeters
Phase 2 N=1,586 Automated Real-time Feedback on CPR Study
Heart Arrest
Primary: Rate of ROSC During the Prehospital Resuscitation — 361; 345 Participants — p=0.96
N/A N=48 Hemodynamic Effects of Standard Cardiopulmonary Resuscitation (CPR), Active Compression Decompression CPR With an Inspiratory Impedance Device, and Standard CPR With an Intrathoracic Pressure Regulator During Out-of-hospital Cardiac Arrest
Cardiac Arrest · Sudden Cardiac Death
Primary: Mean Systolic and Diastolic Blood Pressures — 80.38; 121.21; 61.37; 15.52 mmHg
N/A N=274 Pre-arrival Instructions Effect on Bystander Cardiopulmonary Resuscitation (CPR).
Heart Arrest · Cardiac Arrest · Cardiopulmonary Arrest
Primary: Incidence of Bystander Cardiopulmonary Resuscitation (CPR) in Out of Hospital Cardiac Arrest (OHCA) — 11; 19; 42; 25 participants — p=0.41
Phase 4 N=23,687 Continuous Chest Compressions vs AHA Standard CPR of 30:2
Out of Hospital Cardiac Arrest
Primary: Number of Participants Who Survive From the Time of Cardiac Arrest to Hospital Discharge — 1072; 1127 participants
N/A N=336 Ultra-Brief Versus Brief Hands Only CPR Video Training With and Without Psychomotor Skill Practice
Cardiac Arrest
Primary: Median Compression Depth (mm) — 30; 41; 42; 48 millimeters — p=.05
N/A N=28 Impact of 2 Resuscitation Sequences on Management of Simulated Pediatric Cardiac Arrest
Cardiopulmonary Arrest · Pediatric ALL · Resuscitation
Primary: Median Alveolar Ventilation — 276; 370 ml
N/A N=2,260 Effectiveness of Dispatch-Assisted Cardiopulmonary Resuscitation (CPR) Instructions
Cardiac Arrest
Primary: Sensitivity — 1012 Participants
N/A N=1,076 Improving Cardiac Arrest Diagnostic Accuracy of Emergency Medical Dispatchers
Cardiac Arrest
Primary: Number of Participants With Agonal Breathing — 176; 87 Participants
N/A N=14 Open Pilot Trial of a Mind-body Program for Cardiac Arrest Survivors and Their Caregivers
Emotional Distress · Cardiac Arrest
Primary: Recruitment Feasibility Assessed by the Number of Eligible Dyads Enrolled — 7 dyads
Phase 4 N=129 Non Invasive Mechanical Ventilation in Acute Cardiogenic Pulmonary Edema
Acute Cardiogenic Pulmonary Edema
Primary: Number of Patients Who Were Intubated — 5; 4; 10 participants
N/A N=9 Chest Compression and Sustained Inflation
Newborn Infants Having Asystole or Bradycardia at Birth
Primary: Time Needed to Achieve Return of Spontaneous Circulation — 31; 138 seconds — p=0.05
N/A N=412 Survey of Attitudes and Factors Associated With CPR in an Older Population
Cardiac Arrest
Primary: Measure the Intent to Engage in CPR Training or Intent to Perform CPR — 3.6; 4.1 score on a scale
N/A N=63 Bystander Fatigue and CPR Quality Using Continuous Compressions Versus 30:2 Compressions to Ventilation
Cardiac Arrest
Primary: CPR Quality — 324.9; 381.5 Compressions
N/A N=18,822 Effects of a New Dispatcher-Assisted Basic Life Support Training Program
Out of Hospital Cardiac Arrest
Primary: Number of Participants Surviving to Hospital Discharge — 85; 551 Participants — p=0.34
N/A N=115 MIHS Emergency Department CPR Quality Improvement Project
Cardiac Arrest
Primary: CPR Quality-compression Depth — 46.7; 61.6 mm
N/A N=90 Donor After Circulatory Death Heart CAP Trial
Heart Transplant
Primary: Patient Survival — 75 Participants
N/A N=27 SI + CC Versus 3:1 C:V Ratio During Neonatal CPR
Heart Arrest · Birth Asphyxia · Bradycardia
Primary: Return of Spontaneous Circulation — 90; 615 seconds
N/A N=114 Non-invasive Ventilation Versus Continuous Positive Airway Pressure in Cardiogenic Pulmonary Edema
Cardiogenic Pulmonary Oedema
Primary: Need for an Endotracheal Intubation Within Seven Days After Onset of Cardiopulmonary Edema at the Intensive Care Unit — 5; 5 Participants — p=1.000
N/A N=27 Tourniquets Increase Proximal Pressure
Blood Pressure
Primary: Systolic Blood Pressure During Application of the CAT Tourniquets — 129; 76 mmHg
N/A N=30 Remote Ischemic Conditioning to Enhance Resuscitation (RICE) Pilot
Cardiac Arrest
Primary: Attrition — 0; 0 Participants
Phase 2 N=397 Calcium for Out-of-Hospital Cardiac Arrest
Heart Arrest, Out-Of-Hospital
Primary: Number of Participants With Sustained Return of Spontaneous Circulation — 37; 53 Participants
N/A N=677 Unexpected Cardiac Arrest in Intensive Care Unit
Heart Arrest
Primary: Number of Patients With Unexpected Cardiac Arrest — 677; 30,722 Participants
N/A N=3,194 Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation
Out of Hospital Cardiac Arrest
Primary: Number of Participants Surviving at Hospital Discharge — 135; 216 Participants
N/A N=5 Pre-hospital ECMO in Advanced Resuscitation in Patients With Refractory Cardiac Arrest. ( SUB30 )
Death, Sudden, Cardiac · Out-Of-Hospital Cardiac Arrest · Ventricular Fibrillation
Primary: Proportion of Patients Successfully Established With Pre-hospital ECPR — 0 Participants
N/A N=47 Synchronized Cardiac Assist for Cardiogenic Shock
Shock, Cardiogenic · High Risk Percutaneous Coronary Interventions
Primary: Number of Participants With Device and Procedure Related Serious Adverse Events — 11; 5 Participants
N/A N=42 Comparison of Bystander Fatigue and CPR Quality When Using Two Different CPR Ratios.
Cardiac Arrest
Primary: CPR Quality — 128.5; 126.6 count of chest compressions
Phase 1 N=192 Automatic External Defibrillation Monitoring in Cardiac Arrest
Death, Sudden, Cardiac · Ventricular Fibrillation · Tachycardia, Ventricular
Primary: Number of Participants Without Defibrillation — 94; 97 participants