N/A N=30 Effect of Local Anaesthetic Volume on Axillary Brachial Plexus Block Duration
Brachial Plexus Blockade
Primary: Overall Duration of Sensory Block. — 165; 188 minutes — p=<0.001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=49 Efficacy of Injected Local Anesthetic vs Topical Anesthetic in Cosmetic Injectable Fillers.
Anesthesia
Primary: Participants Anesthetic Preference — 32; 16 participant preference selection
Phase 4 N=25 Effectiveness Study of Different Local Anesthetic Mixtures
Pain
Primary: Length of Action — 6.63; 7.02; 7.48; 7.16 minutes — p=0.359
N/A N=20 Effect of Local Anaesthetic Dilution on the Characteristics of Ultrasound Guided Axillary Brachial Plexus Block
Brachial Plexus Blockade
Primary: Onset of Axillary Block — 8.75; 6.25 minutes — p=0.03
Early Phase 1 N=70 Comparison of Chloroprocaine vs Lidocaine for Epidural Anesthesia in Cesarean Delivery
Surgical Anesthesia, Cesarean Section
Primary: The Onset Time to Surgical Anesthesia — 558; 655 seconds — p=0.10
N/A N=154 Effect of Local Anesthetic Dose on Interscalene Block
Shoulder Arthroscopy · Interscalene Block
Primary: Handgrip Strength — 6.45; 2.98 kg
Phase 4 N=64 Comparison of Two Topical Anesthetics: Benzocaine Versus Pliaglis
Anesthesia of Mucous Membrane
Primary: Measurement of Pain Associated With Injection, in Millimeters, According to Visual Analog Scale — 38.5; 26.9 mm
Phase 4 N=60 Testing the Anesthetic Effectiveness of Three Different Dental Local Anesthetics Injected Next to a Lower First Molar
Anesthetic Effectiveness
Primary: Successful Pulpal Anesthesia. — 37; 27; 22; 33 participants
N/A N=100 Effect of Intra-cuff Lidocaine and Tetracaine on Tracheal Tube-induced Emergence Phenomena
Pharyngitis
Primary: Visual Analogue Scale(0-100mm) by the Subject. — 51; 40; 22; 9 mm
Phase 3 N=211 Chloroprocaine 2% vs Ropivacaine 0.75% in Ultrasound-guided Axillary Nerve Block
Axillary Nerve Block
Primary: Percentage of Participants With Successful Block for Distal Upper Limb Surgeries — 96; 97 Participants
Phase 4 N=43 Chloroprocaine Spinal Anesthesia for Cervical Cerclage (CP Spinal)
Adverse Reaction to Spinal Anesthetic · Maternal Care for Cervical Incompetence
Primary: Time to Resolution of Motor Block — 109; 112 minutes
Phase 4 N=150 Local Anesthetics for Pain Reduction Prior to IV Line Placement
Pain · Local Anesthesia for Peripheral Intravenous Catheterization
Primary: Pain Score Following Anesthetic Administration — 2.81; 1.64; 2.05 units on a scale
N/A N=19 Serum Concentration of Lidocaine After Local Injection During Mohs Micrographic Surgery
Basal Cell Carcinoma · Squamous Cell Carcinoma
Primary: The Number of Subjects With Detectable Serum Lidocaine Concentrations (<0.1 ug/mL) at Each Blood Draw. — 0; 1; 0; 2 Participants
N/A N=76 Local Anesthesia and Pain Perception During an Amniocentesis
Pregnancy
Primary: Intensity of Perceived Maternal Pain as Measured by the Visual Analogue Scale (VAS) — 9.5; 18.4 units on a scale
Phase 4 N=201 Efficacy Study of Articaine Versus Lidocaine as Supplemental Infiltration in Inflamed Molars
Irreversible Pulpitis
Primary: Anesthetic Success Rate of Supplemental Infiltration Injection — 22; 25; 23; 12 Participants — p=.901
Phase 4 N=90 The Effects of Scalp Block With Bupivacaine Versus Levobupivacaine
Hypertension
Primary: Change in Mean Arterial Pressure — 110; 105; 100 mmHg
Phase 3 N=59 The Effect of Local Anesthesia on Control of Intraoperative Physiologic Parameters and Post Operative Comfort
Pain, Procedural
Primary: Post Operative Pain — 13; 10 Participants
Phase 4 N=24 Control of Tourniquet Pain With an Axillary Ring of Subcutaneous Local Anesthetic
Application Site Discomfort · Medical Device Discomfort
Primary: Time in Minutes That Tq Remained Inflated — 30.5; 22.4 Minutes
Phase 4 N=72 Safety of Gebauer's Pain Ease and Gebauer's Ethyl Chloride
Spray · Pain · Safety Issues
Primary: Presence of Microbial Growth (1+ CFU) — 2; 1; 1; 1 Number of samples with 1+ CFU — p=0.317
Phase 4 N=100 The Anesthetic Efficacy of 3% Mepivacaine Plus 2% Lidocaine With 1:100,000 Epinephrine for Lower Jaw Dental Injections
Pain
Primary: Number of Participants Achieving Pulpal Anesthesia Success. — 44; 40 Participants — p=1.00
Phase 3 N=233 Lidocaine + Clonidine for Intraoral Anesthesia in Patients With Diabetes Mellitus Type 2
Diabetes Mellitus · Local Anesthesia
Primary: Duration of Intraoral Local Anesthesia — 132.48; 173.27; 182.09; 195.35 minutes — p=<0.05
N/A N=36 Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy
Thyroid Neoplasms · Goiter, Nodular · Thyroid Nodule
Primary: Intraoperative Fentanyl Administration — 187.5; 185.7; 144.2; 156.3 mcg
Phase 4 N=31 Anesthetic Effect Duration Assessment
Healthy Volunteers
Primary: Duration of Anesthesia(Minutes) — 80; 140; 0; 400 Minutes
Phase 4 N=35 Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment
Endodontic Disease · Post Operative Pain · Symptomatic Irreversible Pulpitis
Primary: Post-operative Pain Level 6 Hours on a Visual Analog Scale — 64.2; 43.1 units on a scale
Phase 4 N=150 Split Face Study of the Duration of Local Anesthetics
Anesthetics, Local
Primary: Time to Return to Baseline Sensation, as Determined by Binary Outcomes (Yes/no) in 15 Minute Increments — 54.34; 49.86; 43.13; 55.78 Minutes — p=0.93
Phase 2 N=33 Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures
Malignant Neoplasm
Primary: Total Dose of Propofol Administered to Each Patient — 2.94; 3.22 mg/kg — p=0.036
Phase 4 N=50 Optimizing Local Anesthetic Concentration for Continuous Lumbar Plexus Nerve Blocks
Hip Arthroplasty · Hip Pain
Primary: Percent Change From Baseline in Quadriceps Femoris Maximum Voluntary Isometric Contraction (MVIC) — 64.1; 68 percentage change from baseline of MVIC
Phase 4 N=50 Lower Third Molar Removal With 2% and 4% Articaine
Impacted Third Molar Tooth · Adverse Reaction to Other Local Anesthetics
Primary: Onset of Anesthetic — 1.5; 1.5 minutes — p=0.192
Phase 2 N=40 Experimental Pain Study to Assess Local Anesthetic Efficacy and Safety of CTY-5339 Anesthetic Spray in Normal Volunteers
Anesthesia
Primary: Duration of Anesthesia as Measured by Pin Prick Test (PPT) for One Spray CTY-5339-A Compared to One Spray CTY-5339-CB — 17.9; 16.4 minutes — p=0.322
N/A N=60 Epidural Anesthesia for Transurethral Resection of The Prostate
Epidural Catheter · Epidural Analgesia · Geriatric Cardiology
Primary: Time to Reach Sensory Block at T10 — 15.25; 10.50; 11.25 Minutes — p=0.05