N/A N=219 Mechanical Ventilation in the Emergency Department: A Prospective Cross-Sectional Study
Respiratory Failure · Mechanical Ventilation · Acute Lung Injury
Primary: To Further Characterize ED Mechanical Ventilation — 500 mL
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=278 Retrospective Review of Mechanically Ventilated Patients Using a Continuous Data Collection System.
Mechanical Ventilation · Acute Respiratory Distress Syndrome · Hypoxic Respiratory Failure
Primary: Successful Extubation — 58; 222 Participants
N/A N=8,151 Third International Study on Mechanical Ventilation
Acute Respiratory Failure
Primary: All-cause Mortality — 2269 Participants
N/A N=269 Evaluation of a Systematic Approach to Weaning From Mechanical Ventilation
Weaning Failure · Complication of Respirator [Ventilator]
Primary: Mortality — 10; 14 participants — p=0.03
N/A N=17 Sleep and Circadian Rhythms in Mechanically Ventilated Patients
Respiratory Failure · Critical Illness
Primary: Percentage of Subjects Who Successfully Undergo Continuous Bedside Polysomnography for at Least 24 Hours. — 9; 8; 5 Participants
N/A N=320 Intensive Alveolar Recruitment Protocol After Cardiac Surgery
Ventilator Induced Lung Injury · Cardiac Disease · Acute Lung Injury
Primary: Severity of Pulmonary Complications in the Post-operative Period — 15; 26 percentage of participants — p=0.016
N/A N=1,705 ED Lung Protective Ventilation to Reduce Complications
Mechanical Ventilation · Ventilator-associated Conditions · ARDS
Primary: Number of Patients That Experience Pulmonary Complications After Admission From the Emergency Department — 171; 38 participants
Phase 2 N=15 Testing the Feasibility of Patient Controlled Sedation for Ventilated ICU Patients
Acute Respiratory Failure · Anxiety
Primary: Aggregate Sedative Exposure During PCS Use (up to 5 Days). — 4; 3.5 units on a scale
N/A N=566 Mode Of Ventilation During Critical IllnEss Pilot Trial
Respiratory Failure
Primary: Ventilator-free Days (VFDs) to Day 28 After Enrollment — 23; 22; 24 Ventilator-free days to day 28
N/A N=33 Development of a Rehabilitation Strengthening and Mobility Program for Ventilator Dependent Older Patients
Respiration, Artificial · Critical Illness · Chronic Disease
Primary: Functional Assessment: Handgrip — 3.6; 1.3 kg
N/A N=120 RCT of Mesh Versus Jet Nebulizers on Clinical Outcomes During Mechanical Ventilation in the Intensive Care Unit
Respiratory Insufficiency
Primary: Venilator Associated Events (VAE) — 44; 40; 4; 2 Participants
N/A N=22 Improving the Sleep and Circadian Rhythms of Mechanically Ventilated Patients
Critical Illness · Sleep Deprivation · Respiratory Failure
Primary: Circadian Timing — 3.6; -2.4 hours — p=0.37
N/A N=32 Effort of Breathing Guided Ventilator Protocol
Ventilators, Mechanical · Work of Breathing
Primary: Percentage of Protocol Recommendations Which Are Accepted by the Clinical Provider — 76 percentage adherant
N/A N=78 AMBU Bag Manual Ventilation vs. Transport Ventilator Mechanical Ventilation for Transport
Oxygenation · Manual Ventilation · Mechanical Ventilation
Primary: The % Change in Mean Artery Blood Pressure — -3.73; 13 % change in mean artery pressure
N/A N=248 Real-time Effort Driven VENTilator Management
Ventilation Therapy; Complications · Diaphragm Disease · Pediatric Respiratory Diseases
Primary: Median Duration of Weaning — 0.09; 1.04; 2.03; 2.10 days — p=.045
Phase 2 N=364 Anxiety Self-Management for ICU Patients Receiving Mechanical Ventilation
Anxiety
Primary: Sedative Exposure — 1; 7; 6 exposures/4-hours per day
Phase 4 N=15 Preventing Depression in People Receiving Mechanical Ventilation in an Intensive Care Unit
Depression
Primary: Recruitment Feasibility, Defined as the Number of Participants Recruited and Administered a Medication Dose Within 48 Hours of Mechanical Ventilation — 7; 8 participants
N/A N=37 Impact of Using Mini-Bronchoalveolar Lavage as a Diagnostic Test for Ventilator-Associated Pneumonia
Ventilator-Associated Pneumonia
Primary: Change in Antibiotic Usage or Exposure — 11.87; 7.76 days — p=0.26
N/A N=7 A Randomized, Controlled Trial of Inspiratory Muscle Training (IMT)in the ICU and CCU
Critically Ill · Respiratory Failure
Primary: Safety and Feasibility of Inspiratory Muscle Training — 3; 3 Participants
N/A N=751 Protocolized Post-Extubation Respiratory Support Study
Mechanical Ventilation Complication · Acute Respiratory Failure · Intubation Complication
Primary: Reintubation — 57; 52 Participants
N/A N=824 Implementation of Nudges to Promote Utilization of Low Tidal Volume Ventilation (INPUT) Study
ARDS · Critical Illness · Acute Respiratory Distress Syndrome
Primary: Fidelity to LPV — 43.3; 19.1; 83.9; 31.0 Percentage of time during first 72 hours
N/A N=53 Electrical Stimulation in Patients With Prolonged Mechanical Ventilation
Respiratory Failure
Primary: Level of Activity of Daily Life — 25.2; 32.0 units on a scale — p=0.652
N/A N=1,609 24 Hour Intensivist Coverage in the Medical Intensive Care Unit
Critically Ill
Primary: MICU Length of Stay — 52.8; 52.6 hours
N/A N=272 Evaluation of the CleanSweep™ Closed Suction System on Length of Mechanical Ventilation and Ventilator-Associated Events
Mechanical Ventilation Complication
Primary: Length of Time on a Mechanical Ventilator — 70.6; 72.2 hours
N/A N=100 High Protein, Core Muscle Rehab, Muscular Electrostimulation in Prolonged Mechanical Ventilation
Prolonged Mechanical Ventilation · Protein Deficiency
Primary: Weaning Rate — 3; 20; 22; 26 Participants
Phase 2 N=31 Vitamin D in Ventilated ICU Patients
Respiratory Failure
Primary: Number of Participants With Plasma 25(OH)D Concentration >30ng/mL at Baseline — 2; 2; 1 participants
N/A N=126 Effects of Respiratory Muscle Training in Mechanically Ventilated Adults
Respiratory Muscle Weakness
Primary: Weaning Time From Mechanical Ventilation — 5; 5 hours — p=0.84
N/A N=26 Volume Guarantee Ventilation in Preterm Infants With Frequent Episodes of Hypoxemia
Episodic Hypoxemia in Mechanically Ventilated Preterm Infants
Primary: Percentage of Time Spent With Arterial Oxygen Saturation < 75% — 5; 4.4 % of time — p=0.44
Phase 4 N=129 Non Invasive Mechanical Ventilation in Acute Cardiogenic Pulmonary Edema
Acute Cardiogenic Pulmonary Edema
Primary: Number of Patients Who Were Intubated — 5; 4; 10 participants
N/A N=2,410 Impact of Early Enteral vs. Parenteral Nutrition on Mortality in Patients Requiring Mechanical Ventilation and Catecholamines
Acute Respiratory Failure · Shock
Primary: Mortality — 422; 443 Participants