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Allergic contact dermatitis

Part of Dermatitis

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for allergic contact dermatitis

7 trials tracked for allergic contact dermatitis: 2 in phase 3 or 4.

7Trials tracked
2Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 1 Phase 3 1 Phase 2 2 Other / NA 3
  1. Phase 4 Bioequivalence of Ethylenediamine Dihydrochloride Study Completed
  2. Phase 3 The Role of Interleukin-1 Beta Targeted Therapy for Patients Suffering From Allergic Contact Dermatitis Completed
  3. Phase 2 Study of Apremilast in Atopic or Contact Dermatitis Completed
  4. Phase 2 Study of the Intradermal Injection of rHuPH20 or Placebo in Participants With Nickel Allergic Contact Dermatitis Completed
  5. N/A NeoMatriX Wound Matrix Collagen Dressing Skin Prick Test Completed
  6. N/A Clinical Evaluation of T.R.U.E. Test Allergens in Children an Adolescents Completed
Show 1 more trials
  1. N/A Red Grape Polyphenol Oral Administration to Women Affected by Nickel-mediated Allergic Contact Dermatitis Completed

Showing the 7 most-cited and recently-updated of 7 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Dermatitis

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Rezpegaldesleukin Demonstrates Significant Efficacy in Moderate to Severe Atopic Dermatitis Patients
Dermatology RCT
Rezpegaldesleukin Demonstrates Significant Efficacy in Moderate to Severe Atopic Dermatitis Patients New treatment shows promise for moderate to severe atopic dermatitis
Rezpegaldesleukin showed significant reductions in EASI scores for adults with atopic dermatitis, demonstrating high efficacy and a manageab…
A new medication shows significant improvement in skin symptoms for adults with moderate to severe atopic dermatitis compared to a placebo.
Abrocitinib significantly improves Investigator Global Assessment response and pruritus in moderate-to-severe atopic dermatitis
Drug Pipeline Meta-analysis
Abrocitinib significantly improves Investigator Global Assessment response and pruritus in moderate-to-severe atopic dermatitis Abrocitinib improves skin severity and itching in eczema patients
This meta-analysis of randomized controlled trials evaluated abrocitinib for patients with moderate-to-severe atopic dermatitis. The analysi…
A new analysis shows abrocitinib helps people with moderate to severe atopic dermatitis reduce skin inflammation and experience less intense…
FcεRII (CD23) serves a regulatory role in IgE homeostasis and may act as a biomarker
Neurology Sys. Review
FcεRII (CD23) serves a regulatory role in IgE homeostasis and may act as a biomarker CD23 May Offer New Insights for Chronic Skin Conditions
This narrative review synthesizes literature from 1980 to 2024 regarding the role of FcεRII (CD23) in skin diseases including atopic dermati…
New research highlights how the CD23 protein may play a key role in managing IgE levels and inflammation in skin diseases like atopic dermat…
Framework Maps Skin-Nose Link in Pediatric Allergy
Allergy & Immunology Guideline
Framework Maps Skin-Nose Link in Pediatric Allergy New framework links eczema and allergic rhinitis in children
A new research framework explores how atopic dermatitis and allergic rhinitis may interact in children, guiding future studies.
A new research framework may explain why eczema and allergic rhinitis often occur together in children, but evidence is limited.
Chronic dermatologic conditions significantly impact psychological distress and health-related quality of life in pediatric patients
Pediatrics Meta-analysis
Chronic dermatologic conditions significantly impact psychological distress and health-related quality of life in pediatric patients Chronic skin conditions cause significant emotional distress in children
This systematic review of 41 studies examines the impact of chronic skin disorders on psychological outcomes and health-related quality of l…
Children with chronic skin conditions like psoriasis and eczema face high rates of anxiety, depression, and social struggles.
Whole goat milk formula reduces atopic dermatitis incidence in infants with parental history
Dermatology RCT
Whole goat milk formula reduces atopic dermatitis incidence in infants with parental history Goat Milk Formula May Lower Risk of Infant Skin Conditions
This randomized clinical trial of 2132 healthy term infants found no difference in atopic dermatitis incidence between whole goat milk and c…
A clinical trial suggests goat milk formula may reduce atopic dermatitis risk in infants, especially those with a family history of the cond…
Precision synbiotic reduces URTI incidence from 85.4% to 55.4% in toddlers
Nutrition & Obesity Medicine RCT
Precision synbiotic reduces URTI incidence from 85.4% to 55.4% in toddlers New synbiotic formula may cut common toddler infections and eczema
This multicenter randomized controlled trial of 390 healthy toddlers aged 1-3 years found that a precision synbiotic significantly reduced u…
A new combination of a specific sugar and healthy bacteria could significantly reduce respiratory infections, diarrhea, and skin issues in t…
Delgocitinib and difamilast rank highest among nonsteroidal topical therapies for pediatric atopic dermatitis
Dermatology Meta-analysis
Delgocitinib and difamilast rank highest among nonsteroidal topical therapies for pediatric atopic dermatitis New Topical Treatments Show Promise for Children with Eczema
This systematic review and network meta-analysis of 3,994 patients evaluated several novel nonsteroidal topical therapies for pediatric atop…
New nonsteroidal topical treatments like delgocitinib and difamilast show promise as steroid-sparing options for children with atopic dermat…
Tissue-resident memory T cells drive disease relapse after biologic and JAK inhibitor discontinuation in atopic dermatitis
Gastroenterology Sys. Review
Tissue-resident memory T cells drive disease relapse after biologic and JAK inhibitor discontinuation in atopic dermatitis Tissue Memory Cells Linked to Atopic Dermatitis Relapse
This narrative review examines the role of tissue-resident memory (TRM) cells in the pathogenesis and chronicity of atopic dermatitis. The a…
New research identifies how certain immune cells may cause atopic dermatitis to return after patients stop using common treatments like biol…
Microbiota-directed therapies for atopic dermatitis currently lack consistent human clinical evidence
Dermatology Sys. Review
Microbiota-directed therapies for atopic dermatitis currently lack consistent human clinical evidence Microbiome therapies for eczema still lack strong evidence
This narrative review examines microbiota-directed therapies including probiotics, postbiotics, and microbial metabolites for atopic dermati…
A new review finds that microbiome-based treatments for atopic dermatitis are promising but backed by limited human data.
Long-term Safety Profile of Dupilumab in Adults with Moderate to Severe Atopic Dermatitis
Dermatology RCT
Long-term Safety Profile of Dupilumab in Adults with Moderate to Severe Atopic Dermatitis Long-term dupilumab use shows low infection rates in skin conditions
A five-year open-label extension study confirms that dupilumab maintains a favorable safety profile regarding infection rates in adult patie…
A five-year study of adults with moderate to severe atopic dermatitis suggests that long-term dupilumab treatment is not linked to increased…
Upadacitinib 30 mg tops JAK inhibitors for moderate-to-severe atopic dermatitis in network meta-analysis
Dermatology Sys. Review
Upadacitinib 30 mg tops JAK inhibitors for moderate-to-severe atopic dermatitis in network meta-analysis Upadacitinib Shows Highest Efficacy for Moderate to Severe Atopic Dermatitis
A systematic review and network meta-analysis of 9 RCTs (4261 adults) found upadacitinib 30 mg had the highest efficacy for EASI-75, IGA-AD …
A review of data from over 4,000 patients suggests upadacitinib may be the most effective oral treatment among several JAK inhibitors for se…