2-octyl cyanoacrylate topical skin adhesives are associated with a 4% incidence of allergic contact dermatitis
Skin glue used in surgery can cause allergic reactions
This meta-analysis of 20 analytic cohorts involving 25,442 patients found a pooled allergic contact dermatitis (ACD) incidence of 4% (95% CI…
A large review of over 25,000 patients shows that some people develop skin rashes after using surgical glue to close wounds.
Review highlights emerging mechanisms for allergic contact dermatitis management
Critical gaps remain in understanding allergic contact dermatitis sensitization thresholds
This narrative review discusses allergic contact dermatitis and notes critical gaps persist regarding tissue-resident memory T cells and pre…
A review of allergic contact dermatitis highlights emerging mechanisms that may support the development of more precise and effective therap…
Research across Dermatitis
Related studies from across the Dermatitis family.
Mesenchymal Stem Cells Show Early Promise in Moderate-to-Severe Atopic Dermatitis
Stem cells show potential for treating severe atopic dermatitis
This meta-analysis pooled data from 236 patients with moderate-to-severe atopic dermatitis to evaluate mesenchymal stem cells. At week 12, 4…
Stem cells from umbilical cord blood and bone marrow may offer a new way to manage moderate to severe atopic dermatitis.
Dupilumab, Lebrikizumab, Tralokinumab All Beat Placebo in Adolescent Eczema, No Clear Winner
New Treatments Show Promise for Severe Adolescent Atopic Dermatitis
This network meta-analysis of 642 adolescents aged 12 to 17 with moderate-to-severe atopic dermatitis found that dupilumab, lebrikizumab, an…
New data shows that dupilumab, lebrikizumab, and tralokinumab may help teens with moderate to severe atopic dermatitis.
Inflammatory memory mechanisms may drive chronic relapse and offer pathways for disease modification in rosacea
New framework explores why rosacea and psoriasis keep returning
This hypothesis-generating critical review explores inflammatory memory, including epigenetic memory and trained immunity, as a framework fo…
Scientists are looking into how the body remembers inflammation, which could help explain why skin conditions like rosacea often flare up re…
Dupilumab for Severe Pediatric Atopic Dermatitis Followed by Vitiligo Three Months Later
Child Develops Vitiligo After Starting Dupilumab
This is a case report and literature review describing an 8-year-11-month-old girl with severe atopic dermatitis who developed vitiligo thre…
A young girl with severe eczema developed vitiligo three months after starting dupilumab, but a link is not proven.
IRF4 acts as a context-encoded mediator in immune compartments and skin repair processes
Understanding the Role of IRF4 in Treating Skin Inflammation Conditions
This narrative review examines the role of Interferon regulatory factor 4 (IRF4) in immune compartments and skin conditions. The review iden…
Scientists are looking at how the IRF4 protein affects skin diseases like psoriasis and eczema to find better ways to manage symptoms.
OM-85 did not significantly reduce time to first wheezing lower respiratory tract illness in high-risk children
Trial shows OM-85 does not prevent early childhood asthma
This randomized controlled trial of 822 children at risk for asthma found no significant difference between OM-85 and placebo regarding time…
A large trial of 822 children found that the drug OM-85 did not reduce the risk of wheezing respiratory illnesses in high-risk infants.
Pathogenic IKBKG variant identified in a pediatric patient with ectodermal dysplasia and immunodeficiency
Genetic testing identifies cause of rare skin and immune condition
This case report and literature review describes a pediatric patient with ectodermal dysplasia with immunodeficiency (EDA-ID) and atopic der…
Genetic testing helped identify a specific gene mutation causing a rare skin and immune disorder in a young patient.
Rezpegaldesleukin Demonstrates Significant Efficacy in Moderate to Severe Atopic Dermatitis Patients
New treatment shows promise for moderate to severe atopic dermatitis
Rezpegaldesleukin showed significant reductions in EASI scores for adults with atopic dermatitis, demonstrating high efficacy and a manageab…
A new medication shows significant improvement in skin symptoms for adults with moderate to severe atopic dermatitis compared to a placebo.
Abrocitinib significantly improves Investigator Global Assessment response and pruritus in moderate-to-severe atopic dermatitis
Abrocitinib improves skin severity and itching in eczema patients
This meta-analysis of randomized controlled trials evaluated abrocitinib for patients with moderate-to-severe atopic dermatitis. The analysi…
A new analysis shows abrocitinib helps people with moderate to severe atopic dermatitis reduce skin inflammation and experience less intense…
FcεRII (CD23) serves a regulatory role in IgE homeostasis and may act as a biomarker
CD23 May Offer New Insights for Chronic Skin Conditions
This narrative review synthesizes literature from 1980 to 2024 regarding the role of FcεRII (CD23) in skin diseases including atopic dermati…
New research highlights how the CD23 protein may play a key role in managing IgE levels and inflammation in skin diseases like atopic dermat…
Framework Maps Skin-Nose Link in Pediatric Allergy
New framework links eczema and allergic rhinitis in children
A new research framework explores how atopic dermatitis and allergic rhinitis may interact in children, guiding future studies.
A new research framework may explain why eczema and allergic rhinitis often occur together in children, but evidence is limited.
Chronic dermatologic conditions significantly impact psychological distress and health-related quality of life in pediatric patients
Chronic skin conditions cause significant emotional distress in children
This systematic review of 41 studies examines the impact of chronic skin disorders on psychological outcomes and health-related quality of l…
Children with chronic skin conditions like psoriasis and eczema face high rates of anxiety, depression, and social struggles.