Research across Stroke
Related studies from across the Stroke family.
Transcranial Magnetic Stimulation reduces motor overflow in focal dystonia and improves stroke and cerebral palsy outcomes
TMS Treatment Shows Potential for Reducing Motor Overflow
This systematic review evaluates the effects of transcranial magnetic stimulation (TMS) on various neurological conditions including stroke,…
Transcranial Magnetic Stimulation may help reduce involuntary movements in patients with focal hand dystonia and other neurological conditio…
DAPT and aspirin show potential for managing minor acute ischemic stroke based on SUCRA rankings
Best stroke treatment may depend on your goal
This network meta-analysis of 26,176 patients evaluated 9 antithrombotic interventions for minor acute ischemic stroke. The analysis suggest…
For minor stroke, the best treatment varies by what matters most: quick recovery, preventing another stroke, or avoiding bleeding.
Ligustilide shows neuroprotective effects across multiple CNS disorders in preclinical models
Ligustilide Shows Potential for Treating Various Brain Disorders
This systematic review of 55 original studies evaluates the neuroprotective potential of ligustilide (LIG) in various neurological condition…
Early research on the compound ligustilide shows potential to protect brain cells from damage caused by stroke, dementia, and other neurolog…
Multidimensional biomarker panels suggest a complex pathological basis for post-stroke depression in the DRN-mPFC circuit
New framework identifies biological markers for depression after a stroke
This narrative review synthesizes evidence regarding the biological drivers of post-stroke depression (PSD). It proposes a framework where P…
A new research framework identifies how different biological factors, like inflammation and chemicals in the brain, combine to cause depress…
Transitional care interventions reduce rehospitalization and improve quality of life in adult stroke survivors
Transitional care helps stroke survivors stay out of the hospital
This systematic review and meta-analysis of 3,520 adult stroke survivors found that transitional care interventions reduced overall rehospit…
Specialized transitional care can cut hospital readmissions for stroke survivors by nearly half within three months of leaving the hospital.
Intravenous thrombolysis does not improve excellent functional recovery in patients with minor acute ischemic stroke
Thrombolytic drugs may not improve recovery for minor strokes
This meta-analysis of randomized controlled trials evaluated intravenous thrombolysis compared to nonthrombolytic standard of care for minor…
New data suggests that using clot-busting drugs might not provide extra benefits for patients with minor, non-disabling strokes.
Adjunctive neuroprotective pharmacotherapy shows modest increase in functional independence for patients with acute ischemic stroke
New data shows potential benefits for patients after stroke
This systematic review and meta-analysis of 4,420 patients evaluated adjunctive neuroprotective pharmacotherapies following endovascular thr…
Adding specific medications to stroke treatment may slightly improve the chance of regaining independence after an acute ischemic stroke.
Endovascular treatment does not improve functional outcomes but increases symptomatic intracranial hemorrhage risk in low NIHSS stroke
Endovascular Treatment Shows No Better Outcome For Certain Stroke Patients
This meta-analysis of patients with low NIHSS scores and Large Vessel Occlusion (LVO) found that endovascular treatment (EVT) did not improv…
A review of stroke treatments shows that endovascular treatment does not improve functional outcomes for some patients but may increase blee…
Neuroinflammation-targeted immunotherapy shows no significant benefit in ischemic stroke meta-analysis
Trial Shows Neuroinflammation Therapies Lack Consistent Benefit for Stroke
This meta-analysis of 3 RCTs (637 patients) found no significant pooled clinical benefit for neuroinflammation-targeted immunotherapies in i…
New research into cell and antibody therapies for stroke shows that these treatments do not yet provide a consistent clinical benefit for pa…
EMG-based bioelectrical feedback improves Fugl-Meyer scores by 9.50 points in post-stroke hemiplegia
Bioelectrical Feedback Improves Motor Function After Stroke
This systematic review and meta-analysis of 8 studies found that EMG-based bioelectrical feedback significantly improved motor function comp…
A review of clinical data shows that bioelectrical feedback can improve motor skills and daily activities for people with post-stroke hemipl…
Tenecteplase shows no significant difference in serious adverse event distribution compared to alteplase
Trial shows tenecteplase is as safe as alteplase for stroke
This multicenter Phase 3 randomized controlled trial post-hoc analysis involved 1577 ischemic stroke patients presenting within 4.5 hours of…
A large study of over 1,500 patients confirms that the clot-busting drug tenecteplase has a similar safety profile to the standard treatment…
PINGS intervention improves systolic blood pressure control to 67% compared to 43% in usual care
Nurse Case Management Improves Blood Pressure for Stroke Survivors
This Phase 3 randomized controlled trial involved 500 adults with stroke and elevated blood pressure. The PINGS intervention, involving nurs…
A new mobile health program using nurse support and phone reminders helped more stroke survivors reach lower blood pressure targets.