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Cardiology
Geranylgeranylacetone mitigates desmin variant-induced atrial cardiomyopathy mechanisms in vitro
A Hidden Heart Flaw May Explain Some Early Atrial Fibrillation
This preclinical in vitro study evaluated HL-1 atrial cardiomyocytes expressing human desmin wild-type or pathogenic variants (p.S13F, p.N34…
A broken heart protein called desmin can silently damage the upper chambers and spark lifelong rhythm problems, while a potential rescue dru…
medRxiv
Apr 16, 2026
Cardiology
Cohort
Deep learning model predicts left atrial imaging from ECG, improves AF and HF risk stratification
Can a simple ECG reading predict your risk for heart rhythm problems?
An observational cohort study using UK Biobank data developed a deep learning model that predicts left atrial imaging indices from 12-lead E…
A routine 10-second heart test can now predict hidden risks for serious heart conditions better than current clinical scores.
medRxiv
Apr 2, 2026