HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Cardiology
Meta-analysis
LGE-CMR positivity associates with higher sudden cardiac death risk in ICD and CRT candidates
Heart Scans Show Higher Sudden Death Risk in Some Patients Before Device Implantation
This systematic review and meta-analysis evaluated 2,494 patients selected for implantable cardioverter defibrillator (ICD) or cardiac resyn…
Heart scans showing scar tissue reveal a 72% higher risk of sudden death for patients needing life-saving heart devices.
Apr 6, 2026
Genetics & Precision Medicine
Cohort
Early age onset predicts MACE in pediatric cardiomyopathy patients with TTN variants
Study finds early age of onset predicts heart events in children with TTN gene cardiomyopathy
A retrospective observational cohort study of 53 pediatric patients with cardiomyopathy and TTN variants found early age-onset disease predi…
Children with TTN gene heart disease who develop symptoms before age six face higher risks of major heart events like failure or severe rhyt…
Frontiers
Apr 3, 2026
Cardiology
Sys. Review
Systematic review explores pathogenesis and emerging treatments for sepsis-induced cardiomyopathy
Review explores potential new treatments for sepsis-related heart problems
A systematic review examined the pathogenesis and treatment landscape for sepsis-induced cardiomyopathy in patients with severe sepsis. The …
New approaches targeting inflammation, calcium, and energy metabolism show potential for treating heart damage in severe sepsis patients.
Frontiers
Apr 2, 2026
Cardiology
Phase II
Phase 2 trial of oral ifetroban in DMD cardiomyopathy reports no safety results yet
Can a new pill help protect the hearts of boys with Duchenne muscular dystrophy?
A phase 2 randomized, double-blind, placebo-controlled trial evaluated low- and high-dose oral ifetroban in 46 males with DMD-associated car…
A new pill called ifetroban is being tested to safely treat heart weakness in boys with Duchenne muscular dystrophy, addressing a leading ca…
CT.gov
Apr 2, 2026
Cardiology
Meta-analysis
SGLT2 inhibitors associated with lower mortality in ATTR-CM patients receiving disease-modifying therapy
Could a common diabetes drug help people with a serious heart condition live longer?
A meta-analysis of 7 observational studies including 7,283 patients with ATTR cardiomyopathy found SGLT2 inhibitor use was associated with l…
A common diabetes drug linked to lower death risk and fewer heart attacks for people with a serious heart condition called transthyretin amy…
Apr 2, 2026