The bile acid-gut microbiota-vitamin D axis may influence pathogenesis of biliary atresia
Bile acid-gut microbiota-vitamin D axis may affect biliary atresia
This systematic review examines the roles of bile acid metabolism, gut microbiota composition, and vitamin D levels in children with biliary…
A new review suggests a link between bile acids, gut bacteria, and vitamin D in biliary atresia, offering potential new treatment targets.
Hepatic steatosis prevalence and impact in autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis
Fatty liver makes autoimmune hepatitis and PBC worse, but not PSC
This systematic review and meta-analysis of 19,898 patients with autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing c…
A large review found fatty liver is common in autoimmune liver diseases and makes outcomes worse for some patients, but not others.
Meta-analysis compares robot-assisted versus laparoscopic surgery for pediatric choledochal cyst
Robotic surgery cuts complications in kids’ liver surgery
This meta-analysis of retrospective studies in children with choledochal cyst found robot-assisted surgery associated with lower rates of bi…
Kids who had robotic surgery for a rare liver cyst faced far fewer serious complications than those who had standard keyhole surgery, a new …
Retrospective analysis of 326 infants with infantile cholestasis reveals etiological spectrum
Simple Blood Marker Could Save Babies from Surgery Delays
This retrospective cohort study evaluated 326 infants diagnosed with infantile cholestasis at the Children's Hospital Affiliated to Shandong…
A new blood test might help doctors find the right cause of baby liver disease faster.
Review of bile acid homeostasis regulation in liver disease and cancer
Review of bile acid regulation for liver disease conditions shows limited evidence
This narrative review examines the regulation of bile acids homeostasis in conditions including cholestasis, hepatic fibrosis, cirrhosis, he…
Bile acid imbalance drives liver disease, but this review found no data proving that regulating it safely treats conditions like cirrhosis o…
Maternal infections, diabetes, and preterm birth associated with neonatal biliary atresia risk
A Mother’s Health May Shape Her Newborn’s Rare Liver Disease Risk
A meta-analysis of 10 retrospective studies in neonates found maternal urogenital infection (OR 1.21), diabetes (OR 1.55), preterm birth (OR…
A mother's diabetes or infection during pregnancy is linked to a higher risk of a serious infant liver condition, offering new clues for ear…