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Home › Conditions › Cholestasis

Cholestasis

Part of Bile Duct Diseases

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Cholestasis

14 trials tracked for Cholestasis: 5 in phase 3 or 4 and 2 with published results. The most-cited published study has 217 citations.

14Trials tracked
5Phase 3 & 4
0Recruiting
2With published results
Phase distribution
Phase 3 5 Phase 2 3 Phase 1 4 Other / NA 2
  1. Phase 3 Effectiveness of Multicomponent Lipid Emulsion in Preterm Infants Requiring Parenteral Nutrition Completed · 217 cited
  2. Phase 3 Compassionate Treatment of Patients With Inborn Errors of Bile Acid Metabolism With Cholic Acid Completed · 64 cited
  3. Phase 3 Compassionate Use of Omegaven in Children Completed
  4. Phase 3 Standard Lipid Therapy vs IVFE Minimization for Prevention of PNALD Completed
  5. Phase 3 Omegaven as Alternative Parenteral Fat Nutrition Completed
  6. Phase 2 Evaluation of Omegaven™ Parenteral Nutrition in Patients With Total Parenteral Nutrition (TPN)-Induced Cholestasis Completed
Show 8 more trials
  1. Phase 2 Open-Label Study of HTD1801 in Adult Subjects With Primary Biliary Cholangitis Completed
  2. Phase 2 Dose Response Study of GSK2330672 for the Treatment of Pruritus in Participants With Primary Biliary Cholangitis Completed
  3. Phase 1 Pharmacokinetics (PKs) and Metabolism of Radiolabelled Linerixibat Completed
  4. Phase 1 Biliary Excretion of Conjugated Bile Acids in Humans Measured by 11C-cholylsarcosine PET/CT Completed
  5. Phase 1 Linerixibat and Obeticholic Acid Drug Interaction Study in Healthy Subjects Completed
  6. Phase 1 Evaluate the Safety, Tolerability, and PK of EP547 in Healthy Subjects and Subjects With Cholestatic or Uremic Pruritus Completed
  7. N/A Compassionate Use of Omegaven to Reverse Parenteral Nutrition Induced Cholestasis Completed
  8. N/A Compassionate Use of an Intravenous Fish Oil Emulsion in the Treatment of Liver Injury in Infants Completed

Showing the 14 most-cited and recently-updated of 14 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Retrospective analysis of 326 infants with infantile cholestasis reveals etiological spectrum
Pediatrics Cohort
Retrospective analysis of 326 infants with infantile cholestasis reveals etiological spectrum Simple Blood Marker Could Save Babies from Surgery Delays
This retrospective cohort study evaluated 326 infants diagnosed with infantile cholestasis at the Children's Hospital Affiliated to Shandong…
A new blood test might help doctors find the right cause of baby liver disease faster.
Frontiers Apr 22, 2026
Review of bile acid homeostasis regulation in liver disease and cancer
Nutrition & Obesity Medicine Sys. Review
Review of bile acid homeostasis regulation in liver disease and cancer Review of bile acid regulation for liver disease conditions shows limited evidence
This narrative review examines the regulation of bile acids homeostasis in conditions including cholestasis, hepatic fibrosis, cirrhosis, he…
Bile acid imbalance drives liver disease, but this review found no data proving that regulating it safely treats conditions like cirrhosis o…
Frontiers Apr 15, 2026