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Home › Conditions › Breast Reconstruction

Breast Reconstruction

0 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Breast Reconstruction

18 trials tracked for Breast Reconstruction: 6 in phase 3 or 4 and 4 with published results. The most-cited published study has 73 citations.

18Trials tracked
6Phase 3 & 4
0Recruiting
4With published results
Phase distribution
Phase 4 3 Phase 3 3 Phase 2 1 Other / NA 11
  1. Phase 3 Mentor Siltex® Contour Profile Gel Mammary Prosthesis Clinical Trial Completed · 73 cited
  2. Phase 4 Impact of the Serratus Plane Block in Pain and the Use of Opioids in Breast Surgery Completed · 44 cited
  3. Phase 4 Effectiveness of Exparel TAP Block in Breast Free Flap Reconstruction Completed · 21 cited
  4. Phase 4 Comparing Local Anesthetics for TAP Block During Abdominally-based Free Flap for Breast Reconstruction Completed · 17 cited
  5. Phase 3 CPG Styles Study: A Study of the Safety of the Contour Profile Gel Breast Implants (CPG Styles Study) Completed
  6. Phase 3 Core Gel Study of the Safety and Effectiveness of Mentor Round Low Bleed Silicone Gel-filled Mammary Prostheses Completed
Show 12 more trials
  1. Phase 2 Immunophenotyping of Fresh Stromal Vascular Fraction From Adipose Derived Stem Cells (ADSC) Enriched Fat Grafts Completed
  2. N/A Safety and Effectiveness of Style 410 Silicone-Filled Breast Implant Study Completed
  3. N/A Evaluation of the Cook Biodesign® Nipple Reconstruction Cylinder (NRC) Completed
  4. N/A The SERI® Surgical Scaffold Use in Reconstruction Post Market Study for Tissue Support and Repair in Breast Reconstruction Surgery Completed
  5. N/A Safety and Effectiveness of Natrelle(TM) Cohesive Round Silicone-Filled Breast Implants Completed
  6. N/A Randomized Controlled Trial of Subcuticular Skin Closure Versus Steri-strip S Closure Completed
  7. N/A The Use of Alloderm Versus Dermacell in Immediate Implant Based Breast Reconstruction Completed
  8. N/A Implementing BREASTChoice Into Practice Completed
  9. N/A Mentor MemoryGel Post-Approval Study Completed
  10. N/A Sientra Sponsored Silimed Gel-Filled Breast Implant Core Clinical Study Completed
  11. N/A A Pilot Study to Evaluate the BodyLogic TM System (Mentor) in Augmentation Mammaplasty Completed
  12. N/A Adjunct Study of Natrelle(TM) Cohesive Round Silicone-Filled Breast Implants Completed

Showing the 18 most-cited and recently-updated of 18 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found Updated — new results For clinicians

Breast Reconstruction: what the trials found

Established evidence includes the use of Serrato, which significantly reduced total opioid usage (p < 0.05) 2. Liposomal bupivacaine was shown to result in post-op pain scores of 4.3 and 3.3 3, while its use alone was noted as an established intervention 4. Several types of silicone-filled breast implants, including Natrelle(TM) [15, 18] and Mentor Round Low Bleed Gel-filled Mammary Protheses (Siltex and Smooth Surface) 7, are established. Additionally, the Mentor Siltex® Contour Profile Gel Mammary Prosthesis 5 and The Contour Profile Gel (CPG) breast implants 6 are established.

N/A

Recent results — preliminary, needs further review

  • Alloderm was evaluated for postoperative duration of drain placements, but results were not statistically significant (p=0.15) 1.

For the clinician treating this condition

  • Serrato is associated with a statistically significant reduction in total opioid usage 2.
  • Liposomal bupivacaine is an established intervention for pain management [3, 4].
  • Multiple silicone-filled and contour profile gel implants are established options for breast reconstruction [5, 6, 7, 15, 18].

AI synthesis of 7 cited trials, updated Jul 8, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
No published articles yet for this condition. Check back soon.