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Clinical insomnia

Part of Insomnia

1 published article · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Insomnia

Related studies from across the Insomnia family.

Daridorexant improves objective and subjective insomnia markers with dose-dependent efficacy across multiple trials
Drug Pipeline Meta-analysis
Daridorexant improves objective and subjective insomnia markers with dose-dependent efficacy across multiple trials New data shows daridorexant helps people with insomnia sleep better
This meta-analysis of 2905 patients found that daridorexant outperformed placebo in both objective and subjective sleep indicators for insom…
Daridorexant shows promise for treating insomnia by improving sleep time and quality, though some side effects are linked to specific doses.
MHT and CBCTi trial protocol evaluates insomnia treatment in perimenopausal women
Psychiatry RCT
MHT and CBCTi trial protocol evaluates insomnia treatment in perimenopausal women New trial plans to test hormone therapy for menopause insomnia
This study protocol describes a randomized controlled trial of 222 perimenopausal women with insomnia and climacteric symptoms. The study wi…
A new clinical trial aims to see if combining hormone therapy with behavioral techniques helps women manage insomnia during the menopausal t…
Sedative-hypnotic use associated with OR 1.29 for incident Alzheimer's Disease
Neurology Meta-analysis
Sedative-hypnotic use associated with OR 1.29 for incident Alzheimer's Disease Meta-analysis links sedative-hypnotic drug use to higher Alzheimer risk
This meta-analysis of observational cohort and nested case-control studies involving 721,354 adults without baseline dementia found that sed…
A large study suggests a link between the use of common sleep medications like benzodiazepines and an increased risk of developing Alzheimer…
Persistent insomnia in heart failure is associated with higher anxiety and lower functional capacity
Cardiology RCT
Persistent insomnia in heart failure is associated with higher anxiety and lower functional capacity Persistent insomnia linked to higher anxiety in heart failure patients
This secondary analysis of a randomized trial involving 400 patients with heart failure identified distinct insomnia trajectories over 12 mo…
A new look at heart failure data shows that lasting sleep issues are tied to higher anxiety and lower physical ability.
CBT-I doubles absolute insomnia remission compared with sleep hygiene across 77 randomized controlled trials
Psychiatry Meta-analysis
CBT-I doubles absolute insomnia remission compared with sleep hygiene across 77 randomized controlled trials CBT-I Doubles Insomnia Remission Compared to Sleep Hygiene
This systematic review and network meta-analysis of 5,731 participants found that CBT-I, SRT+SCT, SRT, and SCT were associated with higher r…
Behavioral therapy for insomnia doubles remission rates, and simpler versions may work too.
Refugee and asylum seeker status is associated with high prevalence of clinically significant sleep disturbances
Pediatrics Meta-analysis
Refugee and asylum seeker status is associated with high prevalence of clinically significant sleep disturbances Refugees face high rates of insomnia and poor sleep
This meta-analysis of 66 studies involving 42,956 participants indicates that refugees and asylum seekers experience significant insomnia se…
Nearly half of refugees experience serious sleep problems, a new analysis finds, with insomnia scores bordering on moderate clinical insomni…
Non-pharmacological interventions may improve sleep quality, quality of life, and anxiety in lung cancer patients
Oncology Meta-analysis
Non-pharmacological interventions may improve sleep quality, quality of life, and anxiety in lung cancer patients Non-drug treatments may improve sleep and anxiety in lung cancer
This systematic review and meta-analysis of 2604 lung cancer patients found that non-pharmacological interventions may have a positive effec…
New data suggests that non-drug therapies can help lung cancer patients sleep better, feel less anxious, and improve their overall quality o…
Exercise combined with CBT is the most consistently supported intervention for improving insomnia sleep quality
ENT (Otolaryngology) Meta-analysis
Exercise combined with CBT is the most consistently supported intervention for improving insomnia sleep quality Exercise combined with therapy shows promise for treating insomnia
This systematic review and network meta-analysis of 31 RCTs involving 2,457 participants found that exercise combined with cognitive behavio…
Combining exercise with cognitive behavioral therapy may improve sleep quality and help people fall asleep faster when dealing with chronic …
Mind-body therapies significantly improve sleep quality in perinatal women with a mean difference of -2.63
Primary Care & Family Medicine Meta-analysis
Mind-body therapies significantly improve sleep quality in perinatal women with a mean difference of -2.63 Mind-body therapies improve sleep quality for perinatal women
This systematic review and meta-analysis of 13 randomized controlled trials involving 782 participants found that mindfulness, Pilates, and …
Yoga, Pilates, and mindfulness may offer a helpful way for pregnant and new mothers to improve their sleep quality during a demanding time.
Exercise improves sleep questionnaire scores for sedentary adults with insomnia across multiple modalities
Physical Medicine & Rehab Sys. Review
Exercise improves sleep questionnaire scores for sedentary adults with insomnia across multiple modalities Different types of exercise improve sleep for people with insomnia
This network meta-analysis of 31 RCTs involving 1,420 participants indicates that various exercise modalities significantly improve sleep qu…
New data shows that various forms of exercise, from aerobic to mind-body routines, can significantly improve sleep quality for those with in…
TCM nursing techniques combined with music-based interventions improve sleep quality in older adults
Psychiatry Meta-analysis
TCM nursing techniques combined with music-based interventions improve sleep quality in older adults Chinese Medicine and Music Improve Sleep in Older Adults
This systematic review and meta-analysis of 838 participants found that traditional Chinese medicine (TCM) nursing techniques combined with …
A review of 838 older adults finds that combining traditional Chinese nursing techniques with music boosts sleep and eases anxiety and pain.
Nurse-administered acupressure reduces PSQI scores by MD -7.61 in menopausal insomnia
Physical Medicine & Rehab Meta-analysis
Nurse-administered acupressure reduces PSQI scores by MD -7.61 in menopausal insomnia Non-drug treatments improve sleep in women after menopause
This meta-analysis of randomized controlled trials in 1648 women after natural menopause found that non-pharmacological interventions, parti…
A large review of trials shows non-drug methods like therapy and exercise significantly improve sleep scores for post-menopausal women.