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Clinical insomnia

Part of Insomnia

1 published article · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Insomnia

Related studies from across the Insomnia family.

Obstructive sleep apnea is associated with a 2- to 3-fold increase in stroke risk
Emergency Medicine Sys. Review
Obstructive sleep apnea is associated with a 2- to 3-fold increase in stroke risk Sleep disorders significantly impact recovery for stroke patients
This narrative review examines the prevalence and impact of sleep disorders, including obstructive sleep apnea (OSA), in stroke patients. Th…
Up to 84% of stroke patients suffer from sleep disorders, which can hinder recovery and increase the risk of future strokes.
Adjunctive acupoint application increases clinical response rates in post-stroke sleep disorders
Neurology Meta-analysis
Adjunctive acupoint application increases clinical response rates in post-stroke sleep disorders Chinese herbal acupoint application may improve sleep after a stroke
This meta-analysis of 608 patients found that adjunctive acupoint application significantly increased trial-defined clinical response rates …
New data suggests that adding herbal acupoint treatments to care can improve sleep quality for people living with sleep disorders after a st…
DORAs show strongest evidence for insomnia while sedating antidepressants vary in antidepressant activity and side effects
Psychiatry Sys. Review
DORAs show strongest evidence for insomnia while sedating antidepressants vary in antidepressant activity and side effects Sedating Antidepressants and DORAs Show Different Benefits for Depression and Insomnia
This narrative review examines sedating antidepressants and dual orexin receptor antagonists (DORAs) for patients with major depressive diso…
New research highlights how different sedating antidepressants and DORAs offer varying levels of support for patients with depression and in…
Syndrome-informed Traditional Chinese Medicine improves sleep quality and reduces blood pressure in patients with comorbid hypertension and insomnia
Diabetes & Endocrinology Meta-analysis
Syndrome-informed Traditional Chinese Medicine improves sleep quality and reduces blood pressure in patients with comorbid hypertension and insomnia Traditional Chinese Medicine may improve sleep and blood pressure
This meta-analysis of 12 trials indicates that syndrome-informed Traditional Chinese Medicine significantly improves sleep quality (SMD -2.2…
New data suggests that syndrome-informed Traditional Chinese Medicine can improve sleep quality and lower blood pressure for adults with bot…
Digital CBTi reduces insomnia severity scores more than telephone or group delivery methods
Oncology Sys. Review
Digital CBTi reduces insomnia severity scores more than telephone or group delivery methods Digital therapy shows promise for cancer patients with insomnia
This systematic review and network meta-analysis of 2040 adult cancer patients found that digital CBTi (dCBTi) significantly reduced ISI sco…
Digital cognitive behavioral therapy can help cancer patients fall asleep faster and stay asleep longer compared to standard care.
Acupuncture-related stimulation improves subjective sleep quality in insomnia, but objective evidence is less secure
Psychiatry Sys. Review
Acupuncture-related stimulation improves subjective sleep quality in insomnia, but objective evidence is less secure Acupuncture shows promise for improving sleep quality in insomnia
This narrative review synthesizes evidence on acupuncture-related peripheral stimulation for insomnia disorder, finding a consistent signal …
New research suggests acupuncture may help people with insomnia improve their sleep quality and reduce the severity of their symptoms.
Orexin receptor antagonists improve sleep continuity by blocking orexin-mediated arousal signaling pathways
Oncology Sys. Review
Orexin receptor antagonists improve sleep continuity by blocking orexin-mediated arousal signaling pathways New drugs target the brain's wake signals to treat insomnia
This narrative review explores the mechanism and physiological effects of orexin receptor antagonists in treating insomnia. The authors conc…
A new class of medications works by blocking the chemicals that keep your body awake, offering a different way to manage sleep disorders.
Tinnitus and insomnia share a bidirectional relationship driven by central nervous system mechanisms
Neurology Sys. Review
Tinnitus and insomnia share a bidirectional relationship driven by central nervous system mechanisms Tinnitus and insomnia are linked by shared brain activity
This systematic review synthesizes evidence on the relationship between tinnitus and sleep disturbance, finding a bidirectional link where i…
Constant ringing in the ears and poor sleep often go hand in hand because they share similar underlying causes in the brain.
Acupuncture and related therapies improve Pittsburgh Sleep Quality Index scores in post-stroke insomnia
Neurology Sys. Review
Acupuncture and related therapies improve Pittsburgh Sleep Quality Index scores in post-stroke insomnia Acupuncture therapies show promise for insomnia after a stroke
This systematic review and network meta-analysis of 8062 patients with post-stroke insomnia found that acupuncture and related therapies wer…
New research suggests that acupuncture and related needle therapies may help patients struggling with sleep issues following a stroke.
Cognitive Behavioral Therapy for Insomnia research highlights digital delivery and management of comorbid conditions
Psychiatry Sys. Review
Cognitive Behavioral Therapy for Insomnia research highlights digital delivery and management of comorbid conditions Mapping the growth of therapy for chronic insomnia and sleep
This bibliometric analysis mapped the evolving landscape of Cognitive Behavioral Therapy for Insomnia (CBT-I) across various medical and psy…
A massive review of thousands of records identifies key research trends and growing focus areas for cognitive behavioral therapy for insomni…
Evaluating Exercise Modalities to Improve Sleep Quality in Breast Cancer Survivors
Oncology Sys. Review
Evaluating Exercise Modalities to Improve Sleep Quality in Breast Cancer Survivors Exercise types linked to better sleep for breast cancer survivors
A network meta-analysis identifies non-linear dose-response relationships between exercise and sleep, highlighting mind-body practices as a …
Specific types of exercise, including mind-body practices, show a link to improved sleep quality for people who have survived breast cancer.
Somnovia digital CBT-I reduces sleep-related worry and dissatisfaction in patients with chronic insomnia
Psychiatry RCT
Somnovia digital CBT-I reduces sleep-related worry and dissatisfaction in patients with chronic insomnia Digital CBT-I Helps Reduce Sleep Worry and Anxiety Symptoms
This secondary analysis of a randomized controlled trial involved 290 adults with chronic insomnia using the somnovia self-guided digital CB…
A digital program called Somnovia may help people with chronic insomnia reduce sleep-related worry and feelings of anxiety over several mont…