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Community-acquired bacterial pneumonia

Part of Community-Acquired Pneumonia

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Community-acquired bacterial pneumonia

3 trials tracked for Community-acquired bacterial pneumonia: 2 in phase 3 or 4.

3Trials tracked
2Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 3 2 Other / NA 1
  1. Phase 3 Study to Compare Delafloxacin to Moxifloxacin for the Treatment of Adults With Community-acquired Bacterial Pneumonia Completed
  2. Phase 3 A Study to Evaluate the Efficacy and Safety of Intravenous Ceftaroline Versus Intravenous Ceftriaxone in the Treatment of Adult Hospitalised Patients With Community-Acquired Bacterial Pneumonia in Asia Completed
  3. N/A Study Evaluating The Safety And Effectiveness In Subjects With Tigecycline Treatment Completed

Showing the 3 most-cited and recently-updated of 3 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Community-Acquired Pneumonia

Related studies from across the Community-Acquired Pneumonia family.

Low-dose corticosteroids reduce 90-day mortality in adults with severe community-acquired pneumonia
Pulmonology & Critical Care Meta-analysis
Low-dose corticosteroids reduce 90-day mortality in adults with severe community-acquired pneumonia Low dose steroids may lower death rates in severe lung infections
This meta-analysis of 4,622 patients found that low-dose corticosteroids (≤400 mg hydrocortisone-equivalent daily) significantly reduced sho…
A review of clinical trials suggests that low-dose corticosteroids can reduce 90-day mortality for adults with severe lung infections like p…
Oral amoxicillin or amoxicillin-clavulanate is non-inferior to intravenous treatment for severe CAP in children
Pediatrics RCT
Oral amoxicillin or amoxicillin-clavulanate is non-inferior to intravenous treatment for severe CAP in children Trial shows oral antibiotics work for children with severe pneumonia
This randomized controlled trial of 1,101 children with severe community-acquired pneumonia in sub-Saharan Africa found that step-down oral …
A large trial in Africa found that switching children from IV to oral antibiotics for pneumonia is as safe and effective as staying on IV tr…
Protocol for comparing azithromycin and doxycycline with beta-lactams in community-acquired pneumonia
Infectious Disease RCT
Protocol for comparing azithromycin and doxycycline with beta-lactams in community-acquired pneumonia New trial to test azithromycin vs doxycycline for pneumonia
This is a protocol for a planned randomized clinical trial involving 1120 adult patients hospitalized with community-acquired pneumonia. No …
A large trial will compare two antibiotic combos for hospitalized pneumonia patients. Which works better?
Short-course antibiotic therapy yields comparable clinical and bacteriological success for adults with community-acquired pneumonia
Rheumatology Meta-analysis
Short-course antibiotic therapy yields comparable clinical and bacteriological success for adults with community-acquired pneumonia Shorter antibiotics work just as well for pneumonia
This meta-analysis of 21 RCTs found that short-course antibiotic therapy (≤5 days) provides comparable clinical, bacteriological, and radiol…
For adults with pneumonia, 5 days or less of antibiotics works as well as longer courses, with fewer severe side effects.
Systemic corticosteroid therapy significantly decreased length of hospital stay and fever duration in children with community-acquired pneumonia
Infectious Disease Meta-analysis
Systemic corticosteroid therapy significantly decreased length of hospital stay and fever duration in children with community-acquired pneumonia Shorter hospital stays and fever for kids with pneumonia using steroids
This systematic review and meta-analysis evaluated systemic corticosteroid therapy versus controls in children with community-acquired pneum…
A large review found that adding steroids to standard antibiotics helped children with pneumonia leave the hospital faster and get over thei…
High mortality rates observed in community-acquired pneumonia patients within intensive care units across low- and middle-income regions
Emergency Medicine Meta-analysis
High mortality rates observed in community-acquired pneumonia patients within intensive care units across low- and middle-income regions Community-acquired pneumonia kills one in three ICU patients in low- and middle-income countries
A systematic review and meta-analysis of 48,707 patients reveals stark mortality risks for community-acquired pneumonia in resource-limited …
A massive review shows that one in three patients with pneumonia admitted to ICUs in low- and middle-income countries dies within a month.
Meta-analysis finds no clear difference between amoxicillin and other antibiotics for community-acquired pneumonia
Pediatrics Meta-analysis
Meta-analysis finds no clear difference between amoxicillin and other antibiotics for community-acquired pneumonia Doctors find amoxicillin works just as well as other drugs for pneumonia
A systematic review and meta-analysis compared amoxicillin and amoxicillin-clavulanate to other antibiotics for community-acquired pneumonia…
New research shows a common antibiotic called amoxicillin works just as well as other options for treating pneumonia in people of all ages.
Hospitalized children with HMPV infection had 28.0% severe CAP rates and higher risks of wheezing and co-infection
Emergency Medicine Cohort
Hospitalized children with HMPV infection had 28.0% severe CAP rates and higher risks of wheezing and co-infection Premature birth and wheezing raise severe HMPV pneumonia risk
This retrospective cohort study examined 878 hospitalized children with human metapneumovirus (HMPV)-positive community-acquired pneumonia (…
A study of 878 children finds premature birth and wheezing are strong predictors of severe HMPV pneumonia.
Nemonoxacin shows similar efficacy to moxifloxacin in hospitalized CAP patients
Drug Pipeline Cohort
Nemonoxacin shows similar efficacy to moxifloxacin in hospitalized CAP patients New pneumonia drug saves money while matching standard care results
This retrospective cohort study of 196 hospitalized patients with community-acquired pneumonia found that nemonoxacin injection had 100.0% c…
A new pneumonia drug saves hospital costs while working just as well as the standard treatment for patients.
Macrolide-resistant Mycoplasma pneumoniae prevalence at 94% in pediatric CAP cohort
Pediatrics Cohort
Macrolide-resistant Mycoplasma pneumoniae prevalence at 94% in pediatric CAP cohort Resistant pneumonia keeps kids sicker for days
This retrospective cohort of 71 pediatric patients in China found a 94.4% prevalence of macrolide-resistant M.
In one Chinese hospital, 94% of child pneumonia cases resisted common antibiotics, leading to longer fevers and hospital stays.
Machine learning models outperformed APACHE-II for predicting mortality in severe community-acquired pneumonia patients with respiratory failure
Rheumatology Cohort
Machine learning models outperformed APACHE-II for predicting mortality in severe community-acquired pneumonia patients with respiratory failure Machine learning models may predict pneumonia death risk better than standard scores in ICU patients
This retrospective cohort study evaluated machine learning models versus the Acute Physiology and Chronic Health Evaluation II (APACHE-II) s…
New computer models predict pneumonia death risk in ICU patients more accurately than standard scores doctors currently use.
tNGS in pediatric LRTIs shows higher Mycoplasma pneumoniae detection in severe vs non-severe CAP
Infectious Disease Cohort
tNGS in pediatric LRTIs shows higher Mycoplasma pneumoniae detection in severe vs non-severe CAP A new test found more germs in severe pediatric pneumonia cases than mild ones
A retrospective, single-center cohort study of 2,299 children with suspected lower respiratory tract infections found that targeted next-gen…
A new test found that severe pediatric pneumonia cases carry more germs than mild ones, revealing a link between specific microbial signatur…