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Home › Conditions › Conduct Disorder

Conduct Disorder

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Conduct Disorder

7 trials tracked for Conduct Disorder: 2 in phase 3 or 4 and 1 with published results. The most-cited published study has 9 citations.

7Trials tracked
2Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 4 2 Phase 2 1 Other / NA 4
  1. Phase 4 Trial of Aripiprazole in the Treatment of CD in Adolescents Completed · 9 cited
  2. Phase 4 Brain Indices of Stimulant Treatment in Drug-Naive Youth at Risk for Substance Use Disorder Completed
  3. Phase 2 Phase 2a Study of Safety and Tolerability of SPN-810 in Children With ADHD and Persistent Serious Conduct Problems Completed
  4. N/A School-Based Mental Health Services for Urban Children Completed
  5. N/A Integrated Smart Speaker Promoting Positive Parenting Among Caregivers of Youth With Challenging Behaviors Completed
  6. N/A Virtual Reality to Improve Social Perspective Taking Completed
Show 1 more trials
  1. N/A Behavioral Treatment for Children With Conduct Problems and Callous-Unemotional Traits Completed

Showing the 7 most-cited and recently-updated of 7 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found Updated — new results For clinicians

Conduct Disorder: what the trials found

Pharmacological interventions have been evaluated for Conduct Disorder. Aripiprazole was studied in a Phase 4 trial involving 12 participants 2.

Adderall was evaluated in a Phase 4 trial of 33 patients, where the ADHD Rating Score (ADHD RS) showed values of 43.18; 39.86; 20.36; 12.71; 20.55; and 19.71 3.

Recent results — preliminary, needs further review

  • The FamilyNet smart speaker/mobile application was evaluated in a trial of 42 participants, but did not produce statistically significant changes in the Strengths and Difficulties Questionnaire (SDQ) for Emotional Problems (p=0.38), Conduct Problems (p=0.19), or Hyperactivity (p=0.44) 1.
  • SPN-810 was evaluated in a Phase 2 trial of 78 participants; the Nisonger Child Behavior Rating Form- Typical Intelligence Quotient (NCBRF-TIQ) Conduct Problem Subscale Score results were 20.4; 25.7; 26.0; 26.0; -0.6; and -3.3 4.

For the clinician treating this condition

  • Aripiprazole and Adderall have been investigated as pharmacological options for Conduct Disorder in Phase 4 trials [2, 3].
  • Adderall was associated with specific ADHD Rating Score (ADHD RS) outcomes in a clinical study 3.

AI synthesis of 4 cited trials, updated Aug 16, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
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Reduced cortical surface area and amygdala volume are associated with youth internalizing and externalizing disorders Brain Imaging Shows Shared Patterns in Youth Mental Disorders
This meta-analysis of 3D T1-weighted magnetic resonance imaging data in youth identifies lower surface area in the insula, entorhinal cortex…
New brain imaging data reveals shared structural patterns in the brains of children and teens with anxiety, depression, ADHD, and conduct di…
Aug 15, 2026