Half of U.S. congenital syphilis cases linked to gaps in prenatal testing and treatment
Half of U.S. congenital syphilis cases linked to gaps in prenatal testing and treatment
An observational analysis of U.S. congenital syphilis cases found that half were associated with gaps in prenatal testing and treatment.
Half of U.S. newborn syphilis cases happen because mothers missed testing or treatment during pregnancy.
CDC report outlines syphilis testing and treatment roles for providers outside prenatal care
How can doctors outside prenatal care help stop syphilis in newborns?
A CDC Vital Signs report describes how health care providers outside of prenatal care settings can help prevent congenital syphilis in pregn…
Doctors outside prenatal care must test and treat pregnant patients for syphilis to stop deadly newborn infections, as many miss traditional…
Research across Treponemal Infections
Related studies from across the Treponemal Infections family.
Doxycycline is the best supported alternative to benzathine penicillin for treating infectious syphilis
Doxycycline shows promise as syphilis treatment alternative
This systematic review and network meta-analysis of 1623 participants evaluates alternative treatments for infectious syphilis. The analysis…
A new review suggests doxycycline may cure syphilis when penicillin isn't an option, but the evidence is weak.
Adequate treatment for maternal syphilis reduces stillbirth odds by 84% in pregnant women
Adequate Treatment for Syphilis Linked to Lower Stillbirth Rates
This meta-analysis of global data indicates that treatment adequacy for maternal syphilis is a primary driver of reduced stillbirth risk. Wh…
Adequate treatment for syphilis in pregnant women is linked to a significant reduction in stillbirth rates compared to inadequate treatment.
TORCH seroprevalence 32.5% in Malaysia; CMV highest, screening urged
TORCH infections found in 32.5% of Malaysian pregnant women and infants
This meta-analysis of 19 reports estimates a 32.5% overall seroprevalence of TORCH infections among pregnant women and infants in Malaysia, …
A meta-analysis finds 32.5% of pregnant women and infants in Malaysia have been exposed to TORCH infections, with CMV most common.
Mucocutaneous manifestations serve as diagnostic indicators for various systemic diseases and paraneoplastic syndromes
Skin and Mouth Signs May Signal Serious Internal Diseases
This narrative review synthesizes the clinical significance of mucocutaneous signs as indicators for conditions including SLE, dermatomyosit…
Certain skin and mouth changes can serve as important clues for doctors to identify underlying conditions like lupus, infections, and metabo…
4CMenB vaccine did not reduce infection rates compared to placebo in MSM population
Trial shows 4CMenB vaccine does not prevent gonorrhea or syphilis
This randomized controlled trial evaluated 4CMenB in 587 men who have sex with men (MSM) recently diagnosed with gonorrhea or infectious syp…
A large trial found that a new vaccine did not reduce the rates of gonorrhea or syphilis infections in men at high risk for these conditions…
Syphilis prevalence is 5.20-fold higher in low-income countries among forcibly displaced populations
High Rates of Syphilis Found Among Displaced Populations
This meta-analysis of 1.1 million test results across 82 reports evaluates the prevalence of syphilis, gonorrhea, chlamydia, and trichomonia…
A large-scale review reveals high rates of syphilis and other infections among refugees, highlighting the need for better screening in these…
Review analyzes political drivers of PMTCT prioritization in Ghana, Mozambique, and Sudan
Strong advocacy networks drive success in ending HIV transmission to babies
This qualitative, cross-country comparative policy analysis reviews documents from Ghana, Mozambique, and Sudan to understand political prio…
United voices and reliable data help nations stop HIV from passing to newborns, but weak leadership blocks progress in some places.
Genomic analysis of 1,707 syphilis genomes reveals lineage-specific diversity and resistance markers across 11 countries
Syphilis Strains Differ Globally And This Changes Vaccine Plans
This research article presents a genomic analysis of 1,707 Treponema pallidum genomes, including 298 new sequences from 11 countries.
New genetic maps reveal syphilis bacteria changes shape by region which impacts vaccine design and drug resistance monitoring efforts global…
CSF Cytokine Panel and Machine Learning for Neurosyphilis Progression Prediction
New Test Could Catch Dangerous Syphilis Complication Early
This observational cohort study evaluated 48 cerebrospinal fluid cytokines in 129 patients with syphilis to distinguish patients from contro…
Imagine getting treated for syphilis — but months later, you start forgetting things, losing balance, or going blind.
Meta-analysis finds doxycycline prophylaxis reduces STI risk in MSM and transgender women
A Common Pill Could Slash Your Risk of Common STIs
A systematic review and meta-analysis of 14 studies in men who have sex with men and transgender women found doxycycline prophylaxis reduced…
A major review of the latest science confirms that a simple antibiotic, taken strategically, offers powerful new protection against chlamydi…
CDC issues new recommendations for diagnostic tests supporting syphilis diagnosis
What's changing in syphilis testing? New CDC recommendations aim to help doctors diagnose
The CDC has published new recommendations for diagnostic tests that can support a diagnosis of syphilis.
New CDC guidelines update how doctors diagnose syphilis to ensure clearer test results and more accurate patient care.
CDC recommends doxycycline postexposure prophylaxis for high-risk populations to prevent syphilis, chlamydia, and gonorrhea
CDC now recommends a pill after sex to help prevent common STIs
The CDC has issued clinical guidelines recommending doxycycline postexposure prophylaxis (doxy PEP) for populations at high risk for syphili…
CDC now recommends a single antibiotic pill after sex to help prevent syphilis, chlamydia, and gonorrhea in high-risk groups.