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Coronary Artery Stenosis

Part of Myocardial ischemia

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Coronary Artery Stenosis

24 trials tracked for Coronary Artery Stenosis: 8 in phase 3 or 4.

24Trials tracked
8Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 6 Phase 3 2 Other / NA 16
  1. Phase 4 XIENCE V® USA Dual Antiplatelet Therapy (DAPT) Cohort Completed
  2. Phase 4 XIENCE V Everolimus Eluting Coronary Stent System (EECSS) China: Post-Approval Randomized Control Trial (RCT) Completed
  3. Phase 4 Kidney Damage in Patients With Moderate Fall in eGFR Completed
  4. Phase 4 EXecutive RCT: Evaluating XIENCE V® in a Multi Vessel Disease Completed
  5. Phase 4 Kidney Damage in Patients With Normal eGFR Completed
  6. Phase 4 XIENCE V: SPIRIT WOMEN Sub-study Completed
Show 18 more trials
  1. Phase 3 SPIRIT PRIME Clinical Trial Completed
  2. Phase 3 SPIRIT III Clinical Trial of the XIENCE V® Everolimus Eluting Coronary Stent System (EECSS) Completed
  3. N/A A Clinical Evaluation of the XIENCE PRIME Small Vessel Everolimus Eluting Coronary Stent System in Japanese Population Completed
  4. N/A ABSORB EXTEND Clinical Investigation Completed
  5. N/A XIENCE V Everolimus Eluting Coronary Stent System (EECSS) China: Post-Approval, Single-Arm Study Completed
  6. N/A A Study to EXhibit Percutaneous Coronary Artery Dilatation With Non-Slip Element Balloon Completed
  7. N/A XIENCE V/PROMUS Everolimus-Eluting Stent System Post-marketing Surveillance Protocol for Japan Completed
  8. N/A A Clinical Evaluation of Absorb™ Bioresorbable Vascular Scaffold (Absorb™ BVS) System in Chinese Population ~ ABSORB CHINA Randomized Controlled Trial (RCT) Completed
  9. N/A XIENCE V® Everolimus Eluting Coronary Stent System USA Post-Approval Study (XIENCE V® USA Long Term Follow-up Cohort) Completed
  10. N/A ABSORB FIRST is a Registry Designed to Evaluate the Safety and Performance of Absorb Bioresorbable Vascular Scaffold (Absorb BVS) Used in Real-world Patients. Completed
  11. N/A Compare the Effectiveness and Safety of Two Different Kinds of Cutting Balloon in Coronary Artery Disease Completed
  12. N/A XIENCE PRIME Japan Post-Marketing Surveillance (PMS) Completed
  13. N/A Absorb IV Randomized Controlled Trial Completed
  14. N/A EXCEL Clinical Trial Completed
  15. N/A Study of BioNIR Drug Eluting Stent System in Coronary Stenosis Completed
  16. N/A ABSORB III Randomized Controlled Trial (RCT) Completed
  17. N/A A Clinical Evaluation of the MINI TREK RX 1.20 mm Coronary Dilatation Catheter in Stenotic Lesions Completed
  18. N/A Pharmacokinetics of Everolimus in Absorb BVS in Patients With Coronary Artery Lesions Completed

Showing the 24 most-cited and recently-updated of 24 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Myocardial ischemia

Related studies from across the Myocardial ischemia family.

IVUS-guided PCI did not significantly reduce target-vessel failure compared to angiography-guided PCI
Cardiology RCT
IVUS-guided PCI did not significantly reduce target-vessel failure compared to angiography-guided PCI Trial shows IVUS guidance does not reduce risk for heart patients
This randomized controlled trial of 2020 patients undergoing complex PCI found that IVUS-guided PCI with stent-optimization criteria resulte…
New data suggests that using special ultrasound imaging during complex heart procedures may not lower the risk of major complications.
IVUS-guided PCI shows no significant difference over angiography-guided PCI for primary outcomes
Cardiology RCT
IVUS-guided PCI shows no significant difference over angiography-guided PCI for primary outcomes Trial shows ultrasound imaging adds no benefit for heart surgery
This randomized controlled trial of 806 patients with unprotected left main coronary artery disease found that IVUS-guided PCI did not signi…
A large trial found that using ultrasound guidance during certain heart procedures did not improve safety or outcomes compared to standard m…
Pre-transplant coronary artery disease increases all-cause mortality and post-transplant cardiovascular events in kidney recipients
Cardiology Meta-analysis
Pre-transplant coronary artery disease increases all-cause mortality and post-transplant cardiovascular events in kidney recipients Pre-existing heart disease increases risks for kidney transplant patients
This meta-analysis of 112,416 kidney transplant recipients found that pre-existing coronary artery disease (CAD) is associated with signific…
Patients with pre-existing coronary artery disease face significantly higher risks of death and graft failure after receiving a kidney trans…
High-intensity interval aerobic exercise improves brachial FMD in coronary artery disease and heart failure
Physical Medicine & Rehab Sys. Review
High-intensity interval aerobic exercise improves brachial FMD in coronary artery disease and heart failure High intensity interval training improves blood flow in heart patients
This network meta-analysis of 6,818 adults with coronary artery disease or chronic heart failure found that high-intensity interval aerobic …
Specific types of intense exercise may improve blood vessel function for people living with heart failure or coronary artery disease.
Higher pan-immune-inflammation value linked to worse outcomes after PCI for ACS
Allergy & Immunology Meta-analysis
Higher pan-immune-inflammation value linked to worse outcomes after PCI for ACS High inflammation scores predict worse heart outcomes in patients with acute coronary syndrome
This systematic review and meta-analysis of 18,715 adults with acute coronary syndrome undergoing PCI found that higher pan-immune-inflammat…
A new analysis shows higher inflammation markers predict death and heart failure in adults with acute coronary syndrome undergoing heart pro…
Colchicine reduces major adverse cardiovascular events in coronary artery disease without increasing serious adverse events
Cardiology Meta-analysis
Colchicine reduces major adverse cardiovascular events in coronary artery disease without increasing serious adverse events Low-dose colchicine reduces heart attack risk for coronary artery disease patients
This systematic review and meta-analysis evaluated colchicine in patients with coronary artery disease and acute coronary syndromes. The ana…
A large analysis shows low-dose colchicine lowers major heart events for coronary artery disease patients without increasing serious risks, …
Staged revascularization shows no significant difference versus immediate revascularization for major adverse cardiovascular events in STEMI and MVD patients
Cardiology Meta-analysis
Staged revascularization shows no significant difference versus immediate revascularization for major adverse cardiovascular events in STEMI and MVD patients Timing of heart surgery does not change survival for a specific heart attack group
This meta-analysis reviewed 5077 patients with ST-segment elevation myocardial infarction and multivessel coronary artery disease comparing …
A large review found that waiting for staged heart surgery did not improve survival or reduce heart attacks compared to immediate surgery fo…
Sirolimus and paclitaxel-coated balloons show similar outcomes for coronary in-stent restenosis
Cardiology Meta-analysis
Sirolimus and paclitaxel-coated balloons show similar outcomes for coronary in-stent restenosis Sirolimus and paclitaxel balloons show similar results for heart disease
This GRADE-assessed systematic review and meta-analysis of 3,633 participants with coronary artery disease found no notable variations betwe…
Two drug-coated balloons for coronary artery disease work about equally well, a new analysis finds.
Polymer-free and biodegradable-polymer drug-eluting stents show comparable outcomes in PCI
Cardiology Meta-analysis
Polymer-free and biodegradable-polymer drug-eluting stents show comparable outcomes in PCI New review shows polymer-free stents work like biodegradable ones for heart patients
A meta-analysis compared polymer-free drug-eluting stents (PF-DES) with biodegradable-polymer drug-eluting stents (BP-DES) in patients under…
A large study of over 11,000 patients found that polymer-free stents are just as safe as older biodegradable ones. Doctors saw no major diff…
Breast arterial calcification on mammography predicts higher cardiovascular event risk in women
Cardiology Meta-analysis
Breast arterial calcification on mammography predicts higher cardiovascular event risk in women Calcium on mammograms signals higher heart risk for women
This systematic review and meta-analysis evaluated breast arterial calcification (BAC) in women across approximately 25,000 participants in …
Calcium seen on mammograms links to higher heart attack risk in women. This large review found a strong connection between breast arterial c…
Mini review examines sudden cardiac death risks in marathon runners across different age groups
Cardiology Sys. Review
Mini review examines sudden cardiac death risks in marathon runners across different age groups Marathon running links to higher heart risk in older men and full-distance participants
This mini review synthesizes evidence on sudden cardiac death (SCD) and coronary artery disease in marathon runners. The authors note that r…
A review of marathon runners shows heart risks vary by age, sex, and race distance, with most events happening near the finish.
Serum resistin levels rise progressively with worsening severity of coronary heart disease and acute myocardial infarction in this meta-analysis
Cardiology Meta-analysis
Serum resistin levels rise progressively with worsening severity of coronary heart disease and acute myocardial infarction in this meta-analysis High blood resistin levels linked to heart disease severity in large analysis
A network meta-analysis of 9,169 subjects reveals that serum resistin levels increase stepwise as coronary heart disease severity worsens. W…
A large network meta-analysis found that higher serum resistin levels are linked to worse coronary heart disease and acute heart attacks.