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De novo oligometastatic disease

Part of Cancer

1 published article · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Cancer

Related studies from across the Cancer family.

SABR Protocol Deviations Linked to Poorer Survival in Oligometastatic Head and Neck Cancer
ENT (Otolaryngology) RCT
SABR Protocol Deviations Linked to Poorer Survival in Oligometastatic Head and Neck Cancer Major protocol deviations cut survival time for head and neck cancer patients
This exploratory analysis of a randomized phase 2 trial (GORTEC 2014-04) in 69 patients with oligometastatic head and neck cancer found that…
Strict radiation quality checks linked to better survival for head and neck cancer patients. Minor or major errors during treatment reduced …
Salvage radiotherapy for limited metastatic relapse in small cell lung cancer after durvalumab
Oncology Cohort
Salvage radiotherapy for limited metastatic relapse in small cell lung cancer after durvalumab Two patients with limited-stage small cell lung cancer had durable disease control after salvage radiotherapy and immunotherapy
This case report describes two patients with limited-stage small cell lung cancer who developed limited metastatic relapse after chemoradiot…
Two limited-stage small cell lung cancer patients stayed stable for over four years after targeted radiation and continued immunotherapy.
Lu-PSMA-617 reduces disease progression versus deferred ADT in oligometastatic HSPC in phase 2 trial
Oncology RCT
Lu-PSMA-617 reduces disease progression versus deferred ADT in oligometastatic HSPC in phase 2 trial Can a targeted radiation drug delay prostate cancer progression without hormone therapy?
A phase 2 randomized controlled trial of 58 men with biochemically recurrent oligometastatic hormone-sensitive prostate cancer found Lu-PSMA…
A targeted radiation drug delayed prostate cancer progression by 20 months in early-stage patients without requiring hormone therapy first.
SMART radiation shows 90% 4-year local control in small oligometastatic abdominopelvic cohort
Urology Phase I
SMART radiation shows 90% 4-year local control in small oligometastatic abdominopelvic cohort Can targeted radiation safely treat small, recurring cancer spots in the abdomen?
A single-arm Phase 1/2 trial in 10 patients with solid tumor abdominopelvic oligometastases found Stereotactic MR-Guided Adaptive Radiation …
Targeted radiation safely controlled small recurring cancer spots in the abdomen for 90% of patients with only mild side effects after four …
Phase 3 Study of Lutetium (177Lu) Vipivotide Tetraxetan in OMPC Patients
Drug Pipeline Phase III
Phase 3 Study of Lutetium (177Lu) Vipivotide Tetraxetan in OMPC Patients Can a new treatment delay prostate cancer from spreading further?
Phase 3 trial evaluates lutetium (177Lu) vipivotide tetraxetan for oligometastatic prostate cancer. Primary outcome: Metastasis Free Surviva…
A new prostate cancer treatment aims to delay cancer spread and spare men from intensive hormone therapy while preserving their quality of l…