Mode
Text Size
Log in / Sign up

Dyspepsia

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Dyspepsia

15 trials tracked for Dyspepsia: 7 in phase 3 or 4 and 3 with published results. The most-cited published study has 87 citations.

15Trials tracked
7Phase 3 & 4
0Recruiting
3With published results
Phase distribution
Phase 4 4 Phase 3 3 Phase 2 3 Other / NA 5
  1. Phase 3 ERADICATE Hp2 - Treating Helicobacter Pylori With RHB-105 Compared to Active Comparator Completed · 87 cited
  2. Phase 3 Compound Sodium Alginate Double Action Chewable Tablet Symptomatic Relief Study Completed · 28 cited
  3. Phase 3 ERADICATE Hp - Treating Helicobacter Pylori With RHB-105 Completed · 11 cited
  4. Phase 4 Clinical Trial of Efficacy and Safety of Kolofort in Functional Dyspepsia Patients Completed
  5. Phase 4 Compliance With Antidepressant Medication in Treatment of Functional Dyspepsia Completed
  6. Phase 4 Comparison of Pantoprazole and Ranitidine in Dyspepsia Completed
Show 9 more trials
  1. Phase 4 Symptomatic Relief of Acute Dyspeptic Pain in Emergency Department With Pantoprazole Completed
  2. Phase 2 Efficacy and Safety of Cannabidiol for Gastroparesis and Functional Dyspepsia Completed
  3. Phase 2 Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus Completed
  4. Phase 2 Effect of Secretin in Functional Dyspepsia and Healthy Subjects Completed
  5. N/A Does Improving Vagal Tone Increase Mitochondrial Bioenergetics Completed
  6. N/A A Randomized, Single Centre, Double-blind, Parallel, Sham-controlled Pilot Study Using gammaCore®-G Completed
  7. N/A Response to Supplement and Placebo in GERD Completed
  8. N/A Carbon-13 (13C)-Spirulina Platensis Gastric Emptying Breath Test (GEBT) Completed
  9. N/A Magnetically Controlled Capsule Endoscopy Feasibility Study in Gastric Motility Completed

Showing the 15 most-cited and recently-updated of 15 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found Updated — new results For clinicians

Dyspepsia: what the trials found

Pharmacological management of dyspepsia includes the use of Compound Sodium Alginate Double Action Chewable Tablets, which demonstrated significant improvements in the Reflux Disease Questionnaire (RDQ) scores across multiple dimensions: GERD (-1.06 to -1.27; p<0.0001), Dyspepsia (-0.80 to -0.98; p=0.0004), and Heartburn (-0.95 to -1.16; p=0.0001) 7.

Treatment of H. pylori infection, a factor relevant in dyspepsia management, was shown to be effective with RHB-105, which demonstrated significant eradication rates in multiple trials (6, 8). Other established pharmacological interventions for related conditions include Pantoprazole 3 and Omeprazole 4.

Clinical trials evaluating Kolofort showed a statistically significant reduction in the severity of functional dyspepsia (FD) symptoms (p=0.041), although changes in the Nepean Dyspepsia Index (NDI) did not reach statistical significance (p=0.435) 2.

Recent results — preliminary, needs further review

  • Magnetically Controlled Capsule Endoscopy is currently under investigation as a new intervention for dyspepsia 1.

For the clinician treating this condition

  • Compound Sodium Alginate Double Action Chewable Tablets significantly improve symptoms across GERD, Heartburn, and Dyspepsia dimensions 7.
  • RHB-105 is an established intervention for the eradication of H. pylori [6, 8].
  • Kolofort has been shown to reduce the severity of functional dyspepsia symptoms, though it did not significantly impact the Nepean Dyspepsia Index (NDI) in clinical trials 2.

AI synthesis of 7 cited trials, updated Jun 28, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.