Meta-analysis links speech features to severity in Parkinsons, cerebral palsy, and ALS
Speech patterns may help track disease severity in Parkinsons and other conditions
This meta-analysis synthesizes evidence from 890 speakers across 5 languages to evaluate a training-free method for assessing speech degrada…
A new computer method tracks Parkinson's and other disease severity by measuring how specific speech sounds change without needing special t…
Current narrative review examines sepsis-associated encephalopathy mechanisms and therapeutic implications
Brain Immune Cells Go Rogue During Sepsis — Scientists May Know How to Reset Them
This narrative review examines the pathophysiology of sepsis-associated encephalopathy, specifically focusing on microglial phenotype change…
During sepsis, the brain's own immune cells turn against it to damage neurons, but new research suggests scientists may know how to reprogra…
Cerebral palsy characteristics and genetic etiology in 9,756 patients from US CPRN sites
Study describes movement and genetic findings in thousands of cerebral palsy patients
This cohort study of 9,756 children and adults with clinician-confirmed cerebral palsy from 22 CPRN sites in the United States describes bas…
A large US study of nearly 10,000 cerebral palsy patients found that Black individuals face greater motor impairment compared to White peers…
Systematic review evaluates SDR, ITB, DBS, and other interventions for functional outcomes in ambulatory children with cerebral palsy
New Surgical Options Are Changing What's Possible for Kids With Cerebral Palsy
This systematic review examined various surgical and neuromodulation interventions for ambulatory children with cerebral palsy, including th…
New surgical and device treatments can reduce movement problems and improve quality of life for children and adults with cerebral palsy.
Systematic review examines mitochondrial dysfunction and neuroinflammation in sepsis-associated encephalopathy
Sepsis Can Silently Damage the Brain — Scientists Now Know Why
This systematic review evaluated interventions targeting mitochondrial dysfunction and neuroinflammation in sepsis-associated encephalopathy…
Sepsis survivors often face lasting brain damage driven by cell energy failure and inflammation, a cycle scientists now map to help protect …
Risk-stratified aeromedical certification protocol assessed in 22 military pilots with cerebral cavernous malformations
Military pilots with brain lesions were assessed for flight safety under a new protocol
This retrospective cohort study evaluated a risk-stratified aeromedical certification protocol in 22 military pilots with cerebral cavernous…
Military pilots with stable brain lesions were cleared to fly without restrictions after a personalized safety review found no neurological …
Retrospective cohort study links prenatal and neonatal factors to cPVL in preterm infants
Could early brain monitoring help predict severe brain injury in premature babies?
This retrospective cohort study examined 46 preterm infants to assess the association between various clinical parameters and cerebral periv…
A study found that early brain blood flow measurements link to severe brain injury in premature babies, offering potential clues for future …
Expert ratings of dystonia severity correlate with functional impact in children with cerebral palsy
Expert video ratings linked dystonia severity to function in 27 children with cerebral palsy
This observational study reviewed videos from 27 children with cerebral palsy assessed by pediatric movement disorder specialists.
When experts rated dystonia as more severe in children with cerebral palsy, the kids showed greater difficulty walking and using their hands…
Exercise improves motor function in children with cerebral palsy, with optimal dose range identified
The Right Exercise Dose for Kids With Cerebral Palsy Finally Has a Number
A Bayesian network dose-response meta-analysis of 20 RCTs in children and adolescents with cerebral palsy found that exercise interventions …
A rigorous analysis of 20 clinical trials reveals the optimal exercise dose range that improves movement in children with cerebral palsy — a…
Oral health factors in 500 Chinese children with special needs show high caries prevalence and associations with hygiene
Three in Four Special Needs Kids Have Cavities by Age 17
This retrospective cross-sectional analysis evaluated oral health in 500 children with special health care needs in Nanjing, China.
A careful look at 500 children's dental records points to clear, fixable steps caregivers can start using this week.
Plastic changes in brainstem reticular formation may be involved in spasticity onset across stroke and spinal cord injury
Could brainstem plastic changes trigger spasticity in stroke and spinal cord injury patients?
This systematic review examined pathophysiological similarities in spasticity among humans, primates, and rodents.
Spasticity after stroke or spinal cord injury may stem from plastic changes in the brainstem, though evidence remains limited and controvers…
Cross-sectional study compares PODCI scores in children with cerebral palsy versus general population
Study compares function and quality of life in children with and without cerebral palsy
This cross-sectional study of 7,708 children ages 2-18 years (2,470 with cerebral palsy, 5,238 general population) found statistically signi…
Children with cerebral palsy show different motor function and happiness trends compared to peers, with happiness scores dropping more sharp…