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Home › Conditions › Hearing Loss

Hearing Loss

13 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Hearing Loss

96 trials tracked for Hearing Loss: 2 in phase 3 or 4.

96Trials tracked
2Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 2 Phase 2 3 Phase 1 1 Other / NA 90
  1. Phase 4 Treating Hearing Loss to Improve Mood and Cognition in Older Adults Completed
  2. Phase 4 Bilateral Benefit in Adult Users of the HiRes 90K Bionic Ear System Completed
  3. Phase 2 Antioxidation Medication for Noise-induced Hearing Loss Completed
  4. Phase 2 Evaluation of the Presence of SENS-401 in the Perilymph Completed
  5. Phase 2 Clinical Trial of the "Living Well With Hearing Loss Workshop" Completed
  6. Phase 1 Speech Recognition Training in Children With Hearing Loss Completed
Show 44 more trials
  1. N/A Safety and Efficacy of the Vibrant Soundbridge (VSB) for Mixed and Conductive Hearing Losses Completed
  2. N/A Clinical Study of Released Unitron RIC and BTE Hearing Aid Models Completed
  3. N/A MyPhonak App Junior Pediatric Usability and Benefit Investigation Completed
  4. N/A Evaluation of a Revised Indication for Determining Adult Cochlear Implant Candidacy Completed
  5. N/A Long Term Safety of the Sonitus SoundBite System Completed
  6. N/A A Standard Music Program Compared to an Optimized Music Program Completed
  7. N/A Clinical Performance, Safety and Patient Reported Outcomes of an Active Osseointegrated Steady-State Implant System Completed
  8. N/A A Comparative, Controlled, Clinical Investigation and Quality Control of a New Hearing Aid Completed
  9. N/A Nucleus Hybrid L24 Extended Duration Post Approval Study Completed
  10. N/A Clinical Applications for Time-Compressed Speech Tests Completed
  11. N/A Noise Reduction Preferences in Teenagers and Pre-teens Completed
  12. N/A Quality Control of CE-Certified Phonak Hearing Aids - 2020_43 Completed
  13. N/A Restoration of Spectral Resolution With Hearing-aid Amplification Completed
  14. N/A Central Auditory Processing Disorders Associated With Blast Exposure Completed
  15. N/A Direct-to-Consumer Hearing Aids and Listening Effort Completed
  16. N/A Evaluation of Remote Fitting in Adult and Pediatric Users of the HiResolution Bionic Ear System Completed
  17. N/A Validation of Novel BTE and SP Hearing Aid Models Completed
  18. N/A Sound Processing Innovations in Adult and Paediatric Cochlear Implant Recipients. Completed
  19. N/A A Simplified Patient-Centered Educational Tool for Improved Hearing-Aid Outcomes Completed
  20. N/A Clinical Evaluation of the Nucleus 5 Cochlear Implant (CI) System Completed
  21. N/A Safety and Effectiveness of the MED-EL Electric-Acoustic System Completed
  22. N/A At-home Auditory Training Clinical Trial Completed
  23. N/A Hearing Aid Quality and Reliability Study Completed
  24. N/A Ponto Implantation Using a Minimally Invasive Surgical Technique Completed
  25. N/A Home Test of New Sound Processor Completed
  26. N/A Retrospective CI532 Hearing Performance Completed
  27. N/A Usability of the CP950 Sound Processor Completed
  28. N/A Clinical Evaluation of a Cochlear Implant Sound Processor Completed
  29. N/A Cross-sectional Evaluation of the Subjective Performance and Satisfaction With Ponto Sound Processors Completed
  30. N/A North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2 Completed
  31. N/A Applying the Use of Motivational Tools to Auditory Rehabilitation Completed
  32. N/A Evaluation of Extended Wear Technology Completed
  33. N/A Comparison of Hearing Aid Fitting Outcomes Between Self-fit and Professional Fit for MDHearing Smart Hearing Aids Completed
  34. N/A Effect of Hearing Aid Labeling on Speech Understanding Measures Completed
  35. N/A Post-market Clinical Follow-up of a Magnetic Bone Conduction Implant (Cochlear Baha Attract System) Completed
  36. N/A Collection and Characterization of Objective Measures to Explore the Specificity of Algorithms Completed
  37. N/A Benefits of Assistive Listening Device for Speech Intelligibility Completed
  38. N/A In Field Performance of a Hearing Aid Transducer Completed
  39. N/A Variability In Hearing Aid Outcomes In Older Adults Completed
  40. N/A Randomized Trial Comparison of Ototoxicity Monitoring Programs Completed
  41. N/A Innovations in Clinical Care of CE Approved Nucleus Cochlear Implant Recipients Completed
  42. N/A Safety and Efficacy of the Cochlear Nucleus CI422 Cochlear Implant in Adults Completed
  43. N/A fNIRS, Listening Effort, and Motivation Completed
  44. N/A Supplementing Hearing Aids With Computerized Auditory Training Completed

Showing the 50 most-cited and recently-updated of 96 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found Updated — new results For clinicians

Hearing Loss: what the trials found

Pharmacological management of depression in patients with hearing loss was evaluated using duloxetine or escitalopram, which resulted in Hamilton Rating Scale for Depression (HRSD) scores of 12.04 and 13.86, respectively 6.

The HiRes 90K Bionic Ear System demonstrated significant improvement in clinical outcomes; post-implant Consonant-Nucleus-Consonant (CNC) scores were recorded at 69.0 compared to pre-implant scores of 4.0 for bilateral users 7.

Recent results — preliminary, needs further review

  • An investigational adaptive directional microphone strategy significantly improved speech clarity, reduced noise annoyance, and improved spatialization (p < 0.05) 14.
  • A prototype mHealth tympanometer demonstrated a classification agreement of 0.81 between audiologist interpretations and machine learning algorithms 5.
  • Health and wellness coaching was associated with hearing aid use of approximately 10 to 12 hours 3.
  • Categorical loudness scaling based fitting showed mixed results compared to behavioral fitting, with varying impacts on monosyllabic word scores in quiet and adaptive sentence scores in noise 1.

For the clinician treating this condition

  • Duloxetine or escitalopram are established options for managing depression in the hearing loss population 6.
  • The HiRes 90K Bionic Ear System is associated with significant improvements in CNC scores post-implantation 7.
  • Investigational adaptive directional microphone strategies show statistically significant improvements in speech clarity and noise annoyance reduction 14.

AI synthesis of 6 cited trials, updated Jun 26, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Systematic review links elevated bilirubin and infections to hearing loss in NICU neonates
Neurology Meta-analysis
Systematic review links elevated bilirubin and infections to hearing loss in NICU neonates What clues in a newborn's body might signal future hearing problems?
A systematic review and meta-analysis of 86 studies in NICU neonates found elevated bilirubin exposure and infective conditions were consist…
High bilirubin levels and serious infections like meningitis are linked to hearing loss in newborns, but study quality varies.
Frontiers Apr 2, 2026

Questions about Hearing Loss

What percentage of US adults over 45 currently use hearing aids based on the survey?

Based on a survey, about 1 in 4 US adults aged 45 and older with hearing loss use hearing aids, with usage increasing with age.

Full answer →
Does using a hearing aid reduce the risk of cognitive impairment in older adults?

Yes, hearing aid use is associated with improved cognitive function and a reduced risk of cognitive impairment in older adults with hearing loss.

Full answer →