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Hearing Loss

11 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Hearing Loss

96 trials tracked for Hearing Loss: 2 in phase 3 or 4.

96Trials tracked

2Phase 3 & 4

0Recruiting

0With published results

Phase distribution

Phase 4 2 Phase 2 3 Phase 1 1 Other / NA 90

Phase 4 Treating Hearing Loss to Improve Mood and Cognition in Older Adults Completed
Phase 4 Bilateral Benefit in Adult Users of the HiRes 90K Bionic Ear System Completed
Phase 2 Antioxidation Medication for Noise-induced Hearing Loss Completed
Phase 2 Evaluation of the Presence of SENS-401 in the Perilymph Completed
Phase 2 Clinical Trial of the "Living Well With Hearing Loss Workshop" Completed
Phase 1 Speech Recognition Training in Children With Hearing Loss Completed

Show 44 more trials

N/A Safety and Efficacy of the Vibrant Soundbridge (VSB) for Mixed and Conductive Hearing Losses Completed
N/A Clinical Study of Released Unitron RIC and BTE Hearing Aid Models Completed
N/A MyPhonak App Junior Pediatric Usability and Benefit Investigation Completed
N/A Evaluation of a Revised Indication for Determining Adult Cochlear Implant Candidacy Completed
N/A Long Term Safety of the Sonitus SoundBite System Completed
N/A A Standard Music Program Compared to an Optimized Music Program Completed
N/A Clinical Performance, Safety and Patient Reported Outcomes of an Active Osseointegrated Steady-State Implant System Completed
N/A A Comparative, Controlled, Clinical Investigation and Quality Control of a New Hearing Aid Completed
N/A Nucleus Hybrid L24 Extended Duration Post Approval Study Completed
N/A Clinical Applications for Time-Compressed Speech Tests Completed
N/A Noise Reduction Preferences in Teenagers and Pre-teens Completed
N/A Quality Control of CE-Certified Phonak Hearing Aids - 2020_43 Completed
N/A Restoration of Spectral Resolution With Hearing-aid Amplification Completed
N/A Central Auditory Processing Disorders Associated With Blast Exposure Completed
N/A Direct-to-Consumer Hearing Aids and Listening Effort Completed
N/A Evaluation of Remote Fitting in Adult and Pediatric Users of the HiResolution Bionic Ear System Completed
N/A Validation of Novel BTE and SP Hearing Aid Models Completed
N/A Sound Processing Innovations in Adult and Paediatric Cochlear Implant Recipients. Completed
N/A A Simplified Patient-Centered Educational Tool for Improved Hearing-Aid Outcomes Completed
N/A Clinical Evaluation of the Nucleus 5 Cochlear Implant (CI) System Completed
N/A Safety and Effectiveness of the MED-EL Electric-Acoustic System Completed
N/A At-home Auditory Training Clinical Trial Completed
N/A Hearing Aid Quality and Reliability Study Completed
N/A Ponto Implantation Using a Minimally Invasive Surgical Technique Completed
N/A Home Test of New Sound Processor Completed
N/A Retrospective CI532 Hearing Performance Completed
N/A Usability of the CP950 Sound Processor Completed
N/A Clinical Evaluation of a Cochlear Implant Sound Processor Completed
N/A Cross-sectional Evaluation of the Subjective Performance and Satisfaction With Ponto Sound Processors Completed
N/A North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2 Completed
N/A Applying the Use of Motivational Tools to Auditory Rehabilitation Completed
N/A Evaluation of Extended Wear Technology Completed
N/A Comparison of Hearing Aid Fitting Outcomes Between Self-fit and Professional Fit for MDHearing Smart Hearing Aids Completed
N/A Effect of Hearing Aid Labeling on Speech Understanding Measures Completed
N/A Post-market Clinical Follow-up of a Magnetic Bone Conduction Implant (Cochlear Baha Attract System) Completed
N/A Collection and Characterization of Objective Measures to Explore the Specificity of Algorithms Completed
N/A Benefits of Assistive Listening Device for Speech Intelligibility Completed
N/A In Field Performance of a Hearing Aid Transducer Completed
N/A Variability In Hearing Aid Outcomes In Older Adults Completed
N/A Randomized Trial Comparison of Ototoxicity Monitoring Programs Completed
N/A Innovations in Clinical Care of CE Approved Nucleus Cochlear Implant Recipients Completed
N/A Safety and Efficacy of the Cochlear Nucleus CI422 Cochlear Implant in Adults Completed
N/A fNIRS, Listening Effort, and Motivation Completed
N/A Supplementing Hearing Aids With Computerized Auditory Training Completed

Showing the 50 most-cited and recently-updated of 96 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found Updated — new results For clinicians

Hearing Loss: what the trials found

Pharmacological management of depression in patients with hearing loss was evaluated using duloxetine or escitalopram, which resulted in Hamilton Rating Scale for Depression (HRSD) scores of 12.04 and 13.86, respectively ⁶.

The HiRes 90K Bionic Ear System demonstrated significant improvement in clinical outcomes; post-implant Consonant-Nucleus-Consonant (CNC) scores were recorded at 69.0 compared to pre-implant scores of 4.0 for bilateral users ⁷.

Recent results — preliminary, needs further review

An investigational adaptive directional microphone strategy significantly improved speech clarity, reduced noise annoyance, and improved spatialization (p < 0.05) ¹⁴.
A prototype mHealth tympanometer demonstrated a classification agreement of 0.81 between audiologist interpretations and machine learning algorithms ⁵.
Health and wellness coaching was associated with hearing aid use of approximately 10 to 12 hours ³.
Categorical loudness scaling based fitting showed mixed results compared to behavioral fitting, with varying impacts on monosyllabic word scores in quiet and adaptive sentence scores in noise ¹.

For the clinician treating this condition

Duloxetine or escitalopram are established options for managing depression in the hearing loss population ⁶.
The HiRes 90K Bionic Ear System is associated with significant improvements in CNC scores post-implantation ⁷.
Investigational adaptive directional microphone strategies show statistically significant improvements in speech clarity and noise annoyance reduction ¹⁴.

AI synthesis of 6 cited trials, updated Jun 26, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

Questions about Hearing Loss

What percentage of US adults over 45 currently use hearing aids based on the survey?

Based on a survey, about 1 in 4 US adults aged 45 and older with hearing loss use hearing aids, with usage increasing with age.

Full answer →

Does using a hearing aid reduce the risk of cognitive impairment in older adults?

Yes, hearing aid use is associated with improved cognitive function and a reduced risk of cognitive impairment in older adults with hearing loss.

Full answer →