GLP-1 receptor agonists associated with lower mortality in HFrEF on GDMT
Heart Failure Patients Cut Death Risk With Common Diabetes Drug
In a retrospective, multicenter cohort study of 1,518 adults with HFrEF on guideline-directed therapy, GLP-1 receptor agonist use was associ…
Adding a common diabetes medication to standard heart failure treatment may significantly lower death rates.
Qiliqiangxin capsule adjunctive therapy reduces cardiovascular death and hospitalization in patients with heart failure with reduced ejection fraction
A Traditional Chinese Capsule Meets Modern Heart Failure Trials
This systematic review and meta-analysis evaluated Qiliqiangxin capsule as adjunctive therapy in 5,580 patients with heart failure with redu…
Adding a traditional Chinese medicine capsule to standard heart failure care reduced deaths and hospital stays in a review of 24 trials.
Remote monitoring chatbot increased GDMT target dose achievement in recently discharged HFrEF patients compared to standard care
A Simple Chatbot After Heart Failure Hospitalization May Keep You Healthier and Out of the Hospital
This randomized controlled trial enrolled 66 patients with heart failure with reduced ejection fraction (HFrEF) recently discharged from the…
For people with heart failure, consistent digital check-ins after leaving the hospital could be the key to getting the right medication stre…
Research across Heart Failure
Related studies from across the Heart Failure family.
Plasticisers disrupt the hypothalamic-pituitary-thyroid axis and potentially contribute to cardiovascular dysfunction
Plasticisers May Link Thyroid Issues to Heart Health Problems
This narrative review explores how plasticisers, including phthalates and bisphenols, interfere with thyroid hormone synthesis, transport, a…
Common chemicals called plasticisers may disrupt thyroid hormones, which could lead to heart issues like high blood pressure and heart failu…
Intradialytic exercise improves cardiovascular function and arterial stiffness in patients on maintenance haemodialysis
Intradialytic Exercise May Improve Heart Function in Dialysis Patients
This meta-analysis of 934 patients receiving maintenance haemodialysis found that intradialytic exercise improved left ventricular ejection …
Exercise during dialysis may improve heart function and blood pressure for patients with heart failure on maintenance hemodialysis.
Four mailer types aim to increase health care proxy documentation in patients with chronic conditions
New trial plans to use mailers to help patients name proxies
This study protocol describes a factorial randomized trial of approximately 20,000 patients with cancer, congestive heart failure, or chroni…
A new study plans to see if different types of mailers can help patients with serious illnesses name a healthcare proxy.
Rheumatic heart disease prevalence in Nepal is 3.1% with significant geographic and temporal disparities
Rheumatic heart disease is much more common in rural Nepal
This meta-analysis of 209,815 participants in Nepal indicates a pooled rheumatic heart disease prevalence of 3.1%. Findings show a higher pr…
New data shows rheumatic heart disease is six times more common in rural areas of Nepal compared to the capital city of Kathmandu.
High-flow nasal cannula shows no significant difference from noninvasive ventilation in acute heart failure
High-flow nasal cannula shows no advantage over noninvasive ventilation
This meta-analysis of 1,282 patients with respiratory failure secondary to acute heart failure found no statistically significant difference…
New data shows that high-flow nasal cannula does not outperform noninvasive ventilation for patients with heart failure and respiratory issu…
Geographic and socioeconomic disparities limit access to mechanical circulatory support and heart transplantation
Heart Devices and Transplants Are Out of Reach for Many
This narrative review with scoping methods examines the global landscape of mechanical circulatory support (MCS) and heart transplantation f…
A new review finds heart transplants and mechanical support are concentrated in wealthy regions, leaving many patients without access.
Breviscapine Add-On May Improve Angina Response in Coronary Heart Disease
Breviscapine May Help Heart Disease Patients With Angina Symptoms
A meta-analysis finds breviscapine plus conventional therapy improves total effective rate in coronary heart disease with angina. Safety dat…
A new analysis finds breviscapine may improve treatment success for people with heart disease and angina. More research is needed to confirm…
Conduction system pacing reduces heart failure hospitalization and cardiomyopathy risk compared to right ventricular pacing
Conduction system pacing may lower heart failure hospital risks
This meta-analysis of randomized controlled trials involving 1466 patients with preserved or mildly reduced LVEF found that conduction syste…
A new type of heart pacing could significantly lower the risk of heart muscle damage and hospital stays for patients with heart failure.
Culturally tailored meal programs reduce hospitalization rates among patients with heart failure
Tailored Navajo meal program reduces heart failure hospital visits
Researchers evaluated a culturally and medically tailored meal program for adults with heart failure in a rural setting. The intervention wa…
A culturally tailored meal program using traditional Navajo foods helped reduce hospital visits for patients living with heart failure.
MASLD linked to 35% higher odds of HFpEF in pooled analysis of 899,629 patients
Liver Disease Linked to Higher Risk of Heart Failure
This meta-analysis of 3 studies (899,629 patients, 47,610 with MASLD) found that MASLD was associated with higher odds of clinically diagnos…
People with metabolic dysfunction-associated steatotic liver disease (MASLD) show a higher risk of developing heart failure with preserved e…
Disulfidptosis may drive cardiomyocyte injury and cytoskeletal collapse under conditions of disulfide stress
New research explores a specific cell death path in heart failure
This narrative review explores the role of disulfidptosis in heart failure and cardiomyocyte injury. The authors suggest that disulfide stre…
Scientists are looking into a process called disulfidptosis to understand how heart cells die during heart failure.
Sarcopenia and Low Grip Strength Correlate with Increased Cardiovascular Risk in Older Adults
Low Muscle Mass and Grip Strength Linked to Heart Risks
A large-scale meta-analysis identifies sarcopenia and low grip strength as significant markers for increased cardiovascular events in elderl…
Lower muscle mass and weaker grip strength are linked to a higher risk of heart disease and stroke in older adults.
Questions about Heart Failure with Reduced Ejection Fraction
Does adding qiliqiangxin to my current treatment help my heart failure with reduced ejection fraction?
Yes, adding qiliqiangxin to your current treatment may reduce cardiovascular death and heart failure hospitalization in HFrEF, based on a large trial and meta-analysis.
Full answer →Will taking Cimlanod cause low blood pressure in patients with heart failure with reduced ejection fraction?
Yes, Cimlanod significantly increases the risk of low blood pressure (hypotension) in patients with heart failure with reduced ejection fraction, according to a meta-analysis.
Full answer →Does Cimlanod lower the chance of dying from heart failure with reduced ejection fraction?
No, Cimlanod does not significantly lower the chance of dying from heart failure with reduced ejection fraction based on current evidence.
Full answer →