Retrospective cohort of 110 children with secondary HLH treated with HLH-94/04 protocol
Young kids with fever and swollen glands need urgent new care plans
This retrospective cohort analysis included 110 children initially diagnosed with secondary hemophagocytic lymphohistiocytosis (sHLH) at a s…
A dangerous immune reaction in toddlers often starts with a cold virus, and new signs help doctors catch it before organs shut down.
R-CHOP immunochemotherapy associated with symptom resolution and complete metabolic response in a case of intravascular large B-cell lymphoma
High Fever and High Ferritin May Signal Rare Blood Cancer
This case report and literature review describes a 60-year-old woman with intravascular large B-cell lymphoma (IVLBCL), fever of unknown ori…
A rare case suggests a specific lab pattern might help doctors find a hidden blood cancer when standard tests fail.
Case report details antiviral and antifungal treatment in a 42-year-old male with primary HLH and EBV infection
A 42-Year-Old Man’s Fever Had a Hidden Genetic Cause
This case report with literature review describes a 42-year-old male with primary hemophagocytic lymphohistiocytosis (HLH) and Epstein–Barr …
This case shows that adults with severe infections may have a hidden genetic immune disorder, changing how doctors look for the cause.
Retrospective cohort of 162 HLH patients shows combined therapy improves survival over monotherapy
Study links certain factors to survival in patients with hemophagocytic lymphohistiocytosis
This retrospective cohort study analyzed 162 patients with hemophagocytic lymphohistiocytosis (HLH) diagnosed across four medical centers.
Survival rates for hemophagocytic lymphohistiocytosis patients improved when combined therapy regimens were used instead of single treatment…
Oral tofacitinib monotherapy with fire needling induced marked regression of cutaneous Rosai-Dorfman disease lesions in a single patient
A pill and a heated needle tamed a stubborn face disease
This case report and literature review describes a 55-year-old female with refractory cutaneous Rosai-Dorfman disease who failed prior thera…
A woman whose face was covered in stubborn red nodules finally saw improvement when doctors tried a surprising combination that crossed medi…