Overlapping IgG4-Related Nephritis and ANCA Glomerulonephritis in Elderly Woman
A Woman's Kidneys Show Two Rare Diseases at Once
An 81-year-old woman presented with concurrent IgG4-related tubulointerstitial nephritis and ANCA-associated glomerulonephritis, highlightin…
A new case report shows two rare kidney diseases can occur together, which helps doctors avoid misdiagnosis and choose the right treatment.
Meta-analysis finds high prevalence of allergy, eosinophilia, and hyper-IgE in IgG4-RD
Allergies may be a hidden warning sign for this rare disease
This meta-analysis of patients with IgG4-related disease found pooled proportions of 0.44 for allergy, 0.22 for eosinophilia, and 0.73 for h…
If you have stubborn allergies along with other puzzling symptoms, new research suggests they could be an early clue to a rare immune diseas…
Research across IgG4-RD
Related studies from across the IgG4-RD family.
Case report and literature review on IgG4-related disease misdiagnosed as pancreatic cancer in a 70-year-old male
A 70-year-old man avoided unnecessary surgery after doctors found a treatable autoimmune condition
This case report and literature review examines a 70-year-old male patient with IgG4-related autoimmune pancreatitis initially suspected as …
A 70-year-old man with a pancreatic mass was found to have a treatable autoimmune disease, sparing him from unnecessary surgery.
Systematic review of anti-IL-5 biologics in hypereosinophilic syndrome kidney disease reports low certainty evidence
New Clues Help Doctors Spot Kidney Trouble in Rare Blood Disease
This systematic review with narrative synthesis evaluates anti-IL-5 and IL-5Rα biologics in patients with histologically confirmed hypereosi…
A new review shows kidney issues in rare blood disorders are tricky to diagnose but may respond well to specific drugs.
Metabolomics analysis reveals distinct B-cell metabolic signatures in IgG4-RD patients compared to healthy controls
Metabolic changes found in B cells of IgG4-related disease patients
This cohort study analyzed B cells from 32 IgG4-RD patients and 31 healthy controls using UPLC-MS/MS-based metabolomics.
A specific panel of 14 chemical markers inside immune cells accurately identifies patients with IgG4-related disease from healthy people.