HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Neurology
Meta-analysis
Intracranial atherosclerosis contributes significantly to global ischemic stroke burden across diverse geographic regions
Understanding the Role of Intracranial Atherosclerosis in Global Stroke Cases
This systematic review of 138 studies examines the epidemiology of intracranial atherosclerosis (ICAD) and its role in ischemic stroke. Find…
Intracranial atherosclerosis is a major cause of stroke worldwide. New data shows it affects millions of people across different continents.
Frontiers
Sep 19, 2026
Neurology
RCT
Tirofiban reduces median infarct volume from 88.2 mm to 48.6 mm in intracranial aneurysms
Trial shows tirofiban reduces brain tissue damage during aneurysm surgery
This Phase 2 randomized trial of 191 adults with unruptured intracranial aneurysms found that intravenous tirofiban combined with dual antip…
A new clinical trial suggests that adding the medication tirofiban can reduce the size of brain tissue damage for patients undergoing aneury…
Aug 9, 2026
Pediatrics
Meta-analysis
Systematic review and meta-analysis links pediatric cerebral AVMs with congenital heart defects and outlines prognostic factors
Brain and heart defects often appear together in children, raising new questions for care
This systematic review and meta-analysis examines the association between cerebral arteriovenous malformations (AVMs) and congenital heart d…
A large review found that brain and heart defects frequently occur together in kids, changing how doctors should watch for complications.
May 24, 2026
Orthopedics & Sports Medicine
Sys. Review
Narrative review suggests endovascular therapy is preferable for persistent primitive hypoglossal artery lesions
Endovascular therapy works better than open surgery for patients with rare brain artery issues
This narrative review examines patients with persistent primitive hypoglossal artery and associated vascular pathologies. The authors synthe…
Patients with rare brain artery problems often need special treatment. Endovascular methods are safer and easier than open surgery for fixin…
Frontiers
May 7, 2026
Neurology
Cohort
PETRA-MRA shows improved image quality and occlusion rates in intracranial aneurysm follow-up
New Scan Clears Metal Scars to See Brain Arteries
A prospective comparative study of 100 patients with intracranial aneurysms found PETRA-MRA image quality improved from postoperative day 1 …
This new imaging trick lets doctors see inside your brain without needles or dyes, making check-ups safer and easier.
Frontiers
Apr 14, 2026
Neurology
Sys. Review
Meta-analysis shows reduced gut alpha diversity in patients with ruptured intracranial aneurysms compared to controls
Could your gut bacteria help protect you from a dangerous brain aneurysm?
This systematic review and meta-analysis evaluated 20 studies involving patients with intracranial aneurysms and controls.
People with ruptured brain aneurysms had less diverse gut bacteria, while specific microbes like Ruminococcus appeared to offer protection a…
medRxiv
Apr 9, 2026
Neurology
Cohort
Pipeline Embolization Device in Small Vessels (<2 mm) Shows 52% 1-Year Occlusion, 16.9% Ischemic Events
Study of Pipeline Device in Small Vessels Shows Mixed Results
A retrospective multicenter cohort of 71 patients with intracranial aneurysms in parent vessels <2 mm found a 1-year complete occlusion rate…
A Pipeline device in tiny brain vessels closed 80% of aneurysms long-term but caused strokes in 17% of patients, with longer devices raising…
Frontiers
Apr 9, 2026