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Home › Conditions › Intracranial Aneurysm

Intracranial Aneurysm

Part of Intracranial Arterial Diseases

4 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Intracranial Aneurysm

23 trials tracked for Intracranial Aneurysm: 5 in phase 3 or 4 and 2 with published results. The most-cited published study has 21 citations.

23Trials tracked
5Phase 3 & 4
0Recruiting
2With published results
Phase distribution
Phase 4 3 Phase 3 2 Other / NA 18
  1. Phase 3 Hypovitaminosis D in Neurocritical Patients Completed · 21 cited
  2. Phase 4 PRET: Patients Prone to Recurrence After Endovascular Treatment Completed · 18 cited
  3. Phase 4 Seizure Prophylaxis in Aneurysm Repair Completed
  4. Phase 4 MAPS Trial: Matrix And Platinum Science Completed
  5. Phase 3 Feasibility Study of the LVIS™ (Low-profile Visualized Intraluminal Support)Device Completed
  6. N/A Neuroform Atlas Stent System Study Completed
Show 17 more trials
  1. N/A Success in Comaneci-assist Coils Embolization Surveillance Study (SUCCESS) Completed
  2. N/A Prospective Study on Embolization of Intracranial Aneurysms With Pipeline™ Embolization Device Completed
  3. N/A The WEB-IT Clinical Study Completed
  4. N/A Pivotal Study of the FRED Stent System in the Treatment of Intracranial Aneurysms Completed
  5. N/A Goal-Directed Intraoperative Fluid Management Using FloTrac© Monitoring in High-Risk Neurosurgical Patients Completed
  6. N/A Pipeline for Uncoilable or Failed Aneurysms Completed
  7. N/A TransForm™ Occlusion Balloon Catheter Registry Completed
  8. N/A Adjunctive Neurovascular Support for Wide-neck Aneurysm Embolization and Reconstruction Completed
  9. N/A Study to Evaluate Cerebral AneurysmFlow Results in Occlusion Completed
  10. N/A Pipeline Flex With SHield Technology Embolization - An International MulticEnter ObservationaL Post Market StuDy Completed
  11. N/A Pivotal Study of the LVIS (Low Profile Visualized Intraluminal Support) Completed
  12. N/A Assessment of the Embolization of Neurovascular Lesions Using the Penumbra Smart Coil Completed
  13. N/A The Registry to Study Safety and Performance of the CORDIS Vascular Reconstruction Device and Delivery System Completed
  14. N/A Contour Neurovascular System - European Pre-Market Unruptured Aneurysm Completed
  15. N/A Coil Assisted Flow Diversion Safety and Performance Study Completed
  16. N/A Study of the Penumbra Coil 400 System to Treat Aneurysm Completed
  17. N/A CorPath® GRX Neuro Study Completed

Showing the 23 most-cited and recently-updated of 23 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Narrative review suggests endovascular therapy is preferable for persistent primitive hypoglossal artery lesions
Orthopedics & Sports Medicine Sys. Review
Narrative review suggests endovascular therapy is preferable for persistent primitive hypoglossal artery lesions Endovascular therapy works better than open surgery for patients with rare brain artery issues
This narrative review examines patients with persistent primitive hypoglossal artery and associated vascular pathologies. The authors synthe…
Patients with rare brain artery problems often need special treatment. Endovascular methods are safer and easier than open surgery for fixin…
Frontiers May 7, 2026
PETRA-MRA shows improved image quality and occlusion rates in intracranial aneurysm follow-up
Neurology Cohort
PETRA-MRA shows improved image quality and occlusion rates in intracranial aneurysm follow-up New Scan Clears Metal Scars to See Brain Arteries
A prospective comparative study of 100 patients with intracranial aneurysms found PETRA-MRA image quality improved from postoperative day 1 …
This new imaging trick lets doctors see inside your brain without needles or dyes, making check-ups safer and easier.
Frontiers Apr 14, 2026
Meta-analysis shows reduced gut alpha diversity in patients with ruptured intracranial aneurysms compared to controls
Neurology Sys. Review
Meta-analysis shows reduced gut alpha diversity in patients with ruptured intracranial aneurysms compared to controls Could your gut bacteria help protect you from a dangerous brain aneurysm?
This systematic review and meta-analysis evaluated 20 studies involving patients with intracranial aneurysms and controls.
People with ruptured brain aneurysms had less diverse gut bacteria, while specific microbes like Ruminococcus appeared to offer protection a…
medRxiv Apr 9, 2026
Pipeline Embolization Device in Small Vessels (<2 mm) Shows 52% 1-Year Occlusion, 16.9% Ischemic Events
Neurology Cohort
Pipeline Embolization Device in Small Vessels (<2 mm) Shows 52% 1-Year Occlusion, 16.9% Ischemic Events Study of Pipeline Device in Small Vessels Shows Mixed Results
A retrospective multicenter cohort of 71 patients with intracranial aneurysms in parent vessels <2 mm found a 1-year complete occlusion rate…
A Pipeline device in tiny brain vessels closed 80% of aneurysms long-term but caused strokes in 17% of patients, with longer devices raising…
Frontiers Apr 9, 2026

Questions about Intracranial Aneurysm

How often do ischemic events happen in patients with small intracranial aneurysms treated with the Pipeline?

Patients with small intracranial aneurysms treated with the Pipeline device experience ischemic events in about 16.9% of cases within one year.

Full answer →