Research across Kidney Diseases
Related studies from across the Kidney Diseases family.
SGLT2 inhibitors provide the greatest risk reduction for kidney outcomes in type 2 diabetes
SGLT2 Inhibitors Lead in Kidney Protection for Diabetes and CKD
This network meta-analysis of 20,521 patients with type 2 diabetes and chronic kidney disease found that SGLT2 inhibitors demonstrated the g…
A new analysis of over 20,000 patients shows SGLT2 inhibitors, semaglutide, and finerenone all protect kidneys in type 2 diabetes and chroni…
Higher CGM-derived time in range is associated with lower odds of diabetic kidney disease
Higher time in range from glucose monitors linked to kidney health
This meta-analysis of 7182 adults with type 1 or type 2 diabetes found that a 10% increase in time in range (TIR) was associated with lower …
Maintaining a steady blood sugar range may help protect the kidneys in people living with type 1 and type 2 diabetes.
High triglyceride-glucose index increases major adverse cardiocerebrovascular events in patients with CKM syndrome
High triglyceride and glucose levels linked to heart and brain risks
This meta-analysis of over 2 million participants found that the highest TyG index category is associated with a 1.20 risk of MACCE compared…
A large study of over 2 million people shows that a specific marker for blood fats and sugar may signal higher risks for heart and brain iss…
Fisetin shows potential as a nutritional senotherapeutic but lacks clinical evidence for chronic kidney disease
Fisetin shows potential for managing chronic kidney disease
This mini review explores the potential of Fisetin as a nutritional senotherapeutic for age-related diseases. The authors conclude that whil…
A natural compound called fisetin may help target age-related issues in the kidneys, though more clinical evidence is needed to confirm its …
AKI Affects 30.7% of Pediatric Liver Transplant Recipients in Pooled Analysis
Identifying risk factors for kidney damage after pediatric liver transplants
This meta-analysis pooled data from 2986 pediatric liver transplant recipients to estimate the incidence of acute kidney injury and examine …
Doctors are looking for ways to protect the kidneys of children undergoing liver transplants, where about 31% face sudden kidney injury.
CD4+ T cell subset imbalance drives renal inflammation and fibrosis in diabetic kidney disease
T Cell Imbalance Linked to Kidney Damage in Diabetic Patients
This narrative review explores the role of CD4+ T cell subset imbalances in the progression of diabetic kidney disease. The authors synthesi…
New research highlights how specific immune cell imbalances may drive inflammation and scarring in people with diabetic kidney disease.
Healthyer dietary patterns and physical activity may improve renal and metabolic outcomes in type 2 diabetes
Healthy eating and exercise help manage kidney disease and diabetes
This systematic review of 31 studies examined dietary patterns, physical activity, and supplements for older adults with type 2 diabetes and…
Specific dietary patterns and regular physical activity show promise in managing blood pressure and kidney health for people with type 2 dia…
Controlled low central venous pressure with nitroglycerin reduces 7-day postoperative AKI by 14.9% absolute risk
Nitroglycerin may lower kidney injury risk after heart surgery
This randomized controlled trial of 505 patients undergoing cardiac surgery found that controlled low central venous pressure (CLCVP) using …
A new trial shows that using nitroglycerin to manage blood pressure during heart surgery can reduce the risk of early kidney damage.
Astragaloside IV significantly reduces renal fibrosis markers and serum creatinine in preclinical animal models
Astragaloside IV Shows Potential for Treating Chronic Kidney Disease
This meta-analysis of preclinical animal studies indicates that Astragaloside IV significantly reduces serum creatinine, blood urea nitrogen…
Early research in animal models suggests that Astragaloside IV may reduce key markers of kidney damage and fibrosis in chronic kidney diseas…
Gut-kidney axis drives sepsis-associated AKI, review argues for microecological and neuromodulatory therapies
New Approaches Target Gut Health to Treat Sepsis Kidney Damage
This systematic review examines the gut-kidney axis as a mechanistic driver of sepsis-associated acute kidney injury and evaluates microecol…
New research explores how targeting the gut-kidney axis could help treat and prevent kidney damage in patients with sepsis.
Four mailer types aim to increase health care proxy documentation in patients with chronic conditions
New trial plans to use mailers to help patients name proxies
This study protocol describes a factorial randomized trial of approximately 20,000 patients with cancer, congestive heart failure, or chroni…
A new study plans to see if different types of mailers can help patients with serious illnesses name a healthcare proxy.
High abdominal aortic calcification index predicts poorer cardiovascular event-free survival in patients with chronic kidney disease
High Abdominal Aortic Calcification Linked to Worse Outcomes in Kidney Disease
This meta-analysis of 1,914 patients found that high abdominal aortic calcification index (ACI) is associated with significantly worse cardi…
High levels of calcium buildup in the aorta are linked to a higher risk of heart issues and lower survival in patients with chronic kidney d…