Research across Kidney Diseases
Related studies from across the Kidney Diseases family.
Dietary fiber reduces indoxyl sulfate by 0.13 mg/dL in humans with CKD
Dietary Fiber May Lower Harmful Gut Metabolites in Kidney Disease
This meta-analysis of 511 human participants and 312 animals found that isolated dietary fiber interventions reduced gut microbial metabolit…
Specific types of dietary fiber may help reduce harmful waste products in the blood for people living with chronic kidney disease.
Sacubitril/valsartan associated with improved renal outcomes in patients with heart failure
New medication shows potential to protect kidneys in heart failure
This meta-analysis evaluated the impact of sacubitril/valsartan compared to standard care or other agents on renal outcomes in adults with h…
A new type of heart medication may slow kidney damage for adults living with heart failure, according to a large review of patient data.
MASLD is associated with higher CKD prevalence and accelerated renal impairment progression
Liver disease and fatty liver are linked to kidney damage
This meta-analysis examines the relationship between metabolic dysfunction-associated steatotic liver disease (MASLD) and chronic kidney dis…
People with fatty liver disease face a higher risk of developing chronic kidney disease, especially as liver scarring worsens.
Ivonescimab-containing chemoimmunotherapy can trigger rare ADAMTS13 inhibitor-positive immune thrombotic thrombocytopenic purpura
New Case Highlights Rare Kidney Risk in Lung Cancer Treatment
This case report and literature review describes a patient with stage IVB lung adenocarcinoma who developed iTTP after receiving an ivonesci…
A single case report identifies a rare blood and kidney condition that can occur during specific lung cancer treatments involving ivonescima…
Combined nutrition and exercise improves physical performance in patients on hemodialysis
Combined nutrition and exercise improve physical performance in dialysis patients
This meta-analysis of 7 trials involving 231 hemodialysis patients found that combined nutrition and exercise improved 6MWT distance, gait s…
Combining nutritional supplements with specific exercises can help people on hemodialysis improve their walking distance and speed.
Chronic kidney disease is associated with increased plaque, calculus, and gingival inflammation
Chronic kidney disease linked to significant oral health problems
This meta-analysis of 24 studies indicates that patients with early- and advanced-stage chronic kidney disease (CKD) exhibit significantly h…
People with chronic kidney disease often face more plaque, gum inflammation, and changes in saliva compared to healthy individuals.
Finerenone reduces UACR by 25% in adults with type 1 diabetes and CKD
Trial shows finerenone reduces kidney markers in type 1 diabetes
This randomized controlled trial of 242 adults with type 1 diabetes and chronic kidney disease found that finerenone reduced UACR by 25% ove…
A new trial suggests the medication finerenone may help protect kidney function in adults with type 1 diabetes and chronic kidney disease.
Mitochondrial metabolic reprogramming and epigenetic modifications drive bidirectional regulation in renal tubular epithelial cells
Mitochondrial Changes and Epigenetics Linked to Diabetic Kidney Disease
This narrative review examines the interplay between mitochondrial metabolism and epigenetic modifications in renal tubular epithelial cells…
New research highlights a two-way link between cell energy production and gene regulation in patients with diabetic kidney disease.
Insulin resistance and hyperinsulinemia drive bidirectional links between biological aging and age-related chronic diseases
Insulin Resistance Links Aging and Chronic Diseases
This narrative review explores the reciprocal relationship between insulin resistance, hyperinsulinemia, and mechanisms of biological aging.…
This review explores how insulin resistance and high insulin levels connect aging to diseases like diabetes, heart disease, and kidney disea…
Frailty associated with higher odds of cognitive impairment in patients with chronic kidney disease
Frailty increases risk of cognitive issues in kidney disease patients
This meta-analysis of 129,868 patients with chronic kidney disease (CKD) found that frailty is associated with a significantly higher risk o…
People with chronic kidney disease who experience frailty are much more likely to face memory and thinking problems than those who stay robu…
Chronic kidney disease prevalence of 13.7% identified across 19 African countries
New data shows high rates of kidney disease across Africa
This systematic review and meta-analysis of 91,723 adults in Africa found a pooled CKD prevalence of 13.7% for stages 1 to 5. The study also…
A large-scale review reveals that over 13% of adults in many African countries live with chronic kidney disease.
GLP-1 receptor agonists and tirzepatide provide cardiovascular benefits across multiple clinical scenarios
Incretin Drugs Show Heart Benefits Across Multiple Conditions
This state-of-the-art review synthesizes evidence regarding incretin analogues, specifically GLP-1 receptor agonists and tirzepatide. The re…
GLP-1 drugs and tirzepatide prove heart benefits in diabetes, obesity, heart failure, and more.