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Large ischemic stroke

Part of Stroke

1 published article · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Stroke

Related studies from across the Stroke family.

Intensive blood pressure lowering reduces severe cerebral oedema risk in acute ischemic stroke patients
Neurology RCT
Intensive blood pressure lowering reduces severe cerebral oedema risk in acute ischemic stroke patients Lowering Blood Pressure Quickly After Stroke May Reduce Brain Swelling
This secondary analysis of a randomized controlled trial involved 1,477 patients with thrombolysed acute ischemic stroke. The study found th…
A large study found that rapidly lowering blood pressure within the first hour after a stroke may reduce the risk of severe brain swelling, …
Thrombolysis plus endovascular therapy for basilar artery occlusion: a trial protocol
Neurology RCT
Thrombolysis plus endovascular therapy for basilar artery occlusion: a trial protocol New trial plans to test stroke treatments for basilar artery
This randomized controlled trial protocol will compare intravenous thrombolysis plus endovascular treatment versus direct endovascular treat…
A large multi-center trial in China aims to see if adding clot-busting drugs improves recovery for patients with a specific type of stroke.
Evaluating High Frequency Repetitive Transcranial Magnetic Stimulation for Post Stroke Cognitive Impairment
Neurology Meta-analysis
Evaluating High Frequency Repetitive Transcranial Magnetic Stimulation for Post Stroke Cognitive Impairment Magnetic brain stimulation may improve memory after a stroke
Meta-analysis results indicate that HF-rTMS significantly improves various memory functions in patients suffering from post-stroke cognitive…
A large review of data suggests that high-frequency magnetic stimulation could help improve memory for people living with post-stroke cognit…
Demographic and clinical factors associated with poststroke cognitive impairment in stroke patients
Cardiology Meta-analysis
Demographic and clinical factors associated with poststroke cognitive impairment in stroke patients Key risk factors identified for cognitive issues after stroke
This meta-analysis examined various risk factors, including age, gender, education level, and comorbidities like hypertension and diabetes, …
New data identifies how age, gender, and underlying conditions like diabetes and high blood pressure impact brain health after a stroke.
Efficacy of Levodopa Based Therapy for Motor and Cognitive Recovery After Stroke
Neurology Meta-analysis
Efficacy of Levodopa Based Therapy for Motor and Cognitive Recovery After Stroke Levodopa does not improve movement after a stroke
A meta-analysis involving 1,257 patients found that adding levodopa to standard stroke rehabilitation yields no significant improvement in m…
A large review of stroke recovery shows that adding levodopa to rehabilitation does not improve physical movement, mood, or thinking.
Dual antiplatelet therapy reduces stroke recurrence in patients with acute mild ischaemic stroke
Neurology Meta-analysis
Dual antiplatelet therapy reduces stroke recurrence in patients with acute mild ischaemic stroke Dual Antiplatelet Therapy Reduces Stroke Risk in Mild Cases
This meta-analysis evaluated dual antiplatelet therapy compared to monotherapy in patients with acute mild ischaemic stroke or TIA. The anal…
New data shows dual antiplatelet therapy can lower stroke recurrence for patients with mild ischemic strokes or TIA, despite higher bleeding…
Non-immersive virtual reality combined with conventional therapy improves upper limb function and activities of daily living
Neurology Meta-analysis
Non-immersive virtual reality combined with conventional therapy improves upper limb function and activities of daily living Virtual reality helps stroke patients regain arm movement and function
This meta-analysis of 12 studies evaluated non-immersive virtual reality (NIVR) as an adjunct to conventional therapy for stroke patients. T…
Adding virtual reality to standard therapy can help stroke survivors improve their arm movement and perform daily tasks more easily.
Botulinum toxin reduces spasticity in adult stroke survivors but shows inconsistent benefits for gait and balance
Neurology Meta-analysis
Botulinum toxin reduces spasticity in adult stroke survivors but shows inconsistent benefits for gait and balance Botulinum Toxin Reduces Spasticity in Adult Stroke Survivors
This meta-analysis of 1740 adult stroke survivors found that botulinum toxin is effective in reducing spasticity. However, the evidence for …
Botulinum toxin can reduce muscle stiffness after a stroke, though its impact on walking and balance remains inconsistent across different p…
Cocaine and amphetamine use significantly increase stroke risk as confirmed by Mendelian randomization
Neurology Meta-analysis
Cocaine and amphetamine use significantly increase stroke risk as confirmed by Mendelian randomization Drug use linked to higher risk of stroke in large study
This systematic review and meta-analysis of 32 studies involving over 100 million participants evaluates the impact of substance use on stro…
New data from over 100 million people shows that using drugs like cocaine and amphetamines significantly increases the risk of having a stro…
Intervention Mapping framework supports development of tailored behavioral interventions for stroke survivor rehabilitation
Rheumatology Meta-analysis
Intervention Mapping framework supports development of tailored behavioral interventions for stroke survivor rehabilitation New framework helps tailor behavior goals for stroke survivors
This systematic review of 9 studies evaluates the Intervention Mapping (IM) framework for designing behaviorally grounded programs for strok…
A structured mapping framework helps create personalized behavioral programs to improve confidence and knowledge for people recovering from …
Transcranial Magnetic Stimulation reduces motor overflow in focal dystonia and improves stroke and cerebral palsy outcomes
Neurology Meta-analysis
Transcranial Magnetic Stimulation reduces motor overflow in focal dystonia and improves stroke and cerebral palsy outcomes TMS Treatment Shows Potential for Reducing Motor Overflow
This systematic review evaluates the effects of transcranial magnetic stimulation (TMS) on various neurological conditions including stroke,…
Transcranial Magnetic Stimulation may help reduce involuntary movements in patients with focal hand dystonia and other neurological conditio…
DAPT and aspirin show potential for managing minor acute ischemic stroke based on SUCRA rankings
Urology Meta-analysis
DAPT and aspirin show potential for managing minor acute ischemic stroke based on SUCRA rankings Best stroke treatment may depend on your goal
This network meta-analysis of 26,176 patients evaluated 9 antithrombotic interventions for minor acute ischemic stroke. The analysis suggest…
For minor stroke, the best treatment varies by what matters most: quick recovery, preventing another stroke, or avoiding bleeding.