Research across Alzheimer's Disease
Related studies from across the Alzheimer's Disease family.
Sedative-hypnotic use associated with OR 1.29 for incident Alzheimer's Disease
Meta-analysis links sedative-hypnotic drug use to higher Alzheimer risk
This meta-analysis of observational cohort and nested case-control studies involving 721,354 adults without baseline dementia found that sed…
A large study suggests a link between the use of common sleep medications like benzodiazepines and an increased risk of developing Alzheimer…
Bibliometric analysis identifies growing research trends and key hubs for short-chain fatty acids in cognitive impairment
Mapping the Growing Research on Gut Health and Memory Loss Diseases
This systematic review provides a bibliometric analysis of 425 WoSCC and 514 Scopus records regarding short-chain fatty acids (SCFAs) and co…
Scientists are tracking how gut-related compounds might help brain health. This review maps out years of research into these important links…
Berberine identified as potential Alzheimer's treatment targeting HMGCR in astrocyte-driven model
New research identifies a potential target for Alzheimer's disease
This guideline presents a computational analysis identifying an autolysosome-astrocyte-associated diagnostic model for Alzheimer's disease, …
Scientists identified a specific gene as a key driver of Alzheimer's and found that the compound berberine may help target it.
Adaptive immune signatures and T cell infiltration characterize pathology in Alzheimer's, Parkinson's, and Lewy Body dementia
Adaptive Immune Signatures Linked to Alzheimer's and Parkinson's Disease
This mini review synthesizes evidence regarding adaptive immune remodeling and T cell responses in neurodegenerative dementias. The authors …
New research highlights how specific immune cell activity may play a role in the progression of Alzheimer's, Parkinson's, and Lewy body deme…
Angiogenic factors in biofluids show no significant difference in Alzheimer's disease
Comparing blood markers to see if they help identify Alzheimer disease
This systematic review and meta-analysis of 18 studies found a small, nonsignificant overall effect size for angiogenic factors in biofluids…
Researchers looked at several proteins in the blood to see if they could help tell the difference between healthy people and those with Alzh…
Exercise training promotes adult hippocampal neurogenesis by influencing the neurochemical environment and cell cycle dynamics
Exercise training may help grow new neurons in the brain
This narrative review synthesizes evidence regarding exercise training and its effects on adult hippocampal neurogenesis in conditions such …
Physical exercise can trigger the growth of new neurons and stem cells, potentially offering new paths for treating brain disorders like Alz…
Hormonal birth control and menopausal hormone therapy associated with greater gray matter volume
Hormonal Birth Control Linked to Greater Brain Volume in Women
This observational study of 459 women found that hormonal birth control (BC) and menopausal hormone therapy (MHT) were associated with incre…
New research suggests that hormonal birth control and menopausal hormone therapy may be linked to larger brain volume and thicker cortex in …
APOE ε4 status does not significantly impact neurocognitive performance in adults with HIV infection
APOE Status Does Not Impact Cognitive Health in HIV Patients
This meta-analysis of 2610 adults with HIV found no significant difference in cognitive performance or diagnosis of neurocognitive impairmen…
A large review of data suggests that the APOE e4 gene does not change cognitive performance or impairment for adults living with HIV.
Plasma p-tau217 and Aβ42/40 biomarkers show high AUC for discriminating amyloid PET positivity
Blood Tests May Help Identify Early Signs of Alzheimer's
This meta-analysis of 9 studies involving 2566 cognitively unimpaired Asian individuals found that plasma p-tau217 (AUC 0.88) and Aβ42/40 (A…
New research shows that specific blood markers can help identify early signs of amyloid buildup in the brain for people without memory loss.
EEG microstate duration and occurrence rates differ significantly between Alzheimer's patients and healthy controls
Brain wave patterns show differences in Alzheimer's and memory loss
This meta-analysis of 16 studies evaluated EEG microstate parameters in patients with Alzheimer's disease (AD) and mild cognitive impairment…
New analysis shows specific brain wave patterns change as memory fades, offering a new way to look at how the brain handles information.
194 miRNAs exhibit widespread changes in Alzheimer's disease and influence key biological pathways
194 microRNAs show widespread changes in Alzheimer's disease
This meta-analysis of 22 studies identifies 194 miRNAs with widespread changes in Alzheimer's disease. The analysis highlights the involveme…
A meta-analysis of 22 studies found 194 microRNAs with widespread changes in Alzheimer's disease, including novel ones. These miRNAs affect …
Combined plasma p-tau217 and tau-PET identify high-risk patients with hazard ratios up to 9.98
Blood Tests and Brain Scans Help Predict Alzheimer Disease Progress
This observational study of 330 cognitively unimpaired, Amyloid-beta positive older adults found that the T+ T+ biomarker profile predicted …
Combining blood tests with brain scans can identify which individuals are at the highest risk for rapid cognitive decline in early Alzheimer…