Dioscin shows therapeutic potential for various liver disorders including MASLD and hepatocellular carcinoma
Plant Compound Dioscin Shows Promise For Liver Disease
This systematic review evaluates the hepatoprotective effects and pharmacokinetics of Dioscin in various liver diseases. The review conclude…
A plant compound called Dioscin may help protect the liver, but human evidence is still missing and high doses carry risks.
Narrative review explores aryl hydrocarbon receptor's dual role in liver injury and protection
Liver's Secret Switch Flips Between Harm and Healing
This narrative review examines the aryl hydrocarbon receptor (AhR) in liver disease. AhR activation drives liver damage through mitochondria…
Your liver has a hidden sensor that pollution can flip to destroy mode but scientists just found how to lock it in repair mode
Review of liver disease immunomodulation strategies notes precision over broad suppression
Your Liver's Immune Cells Play Both Hero and Villain at Once
This narrative review examines immunomodulation approaches for liver diseases, including acute liver injury, HBV infection, MASLD/MASH, fibr…
Liver immune cells can both damage and repair your organ at the same time, a discovery that could unlock new precision treatments for hepati…
MAIT cell frequency decreased in sepsis-related liver injury, with altered phenotype and function in murine models
Liver cells get help from immune defenders during sepsis
This observational cohort study in patients with sepsis-related liver injury (SRLI) and murine models found significantly decreased peripher…
During sepsis, immune defenders actually protect the liver instead of causing damage, offering new hope for patients losing liver function.
Retrospective cohort identifies TIBC and rPLR cutoffs for EBV-IM-related hepatic injury in children
Iron Levels and Blood Counts Predict Liver Trouble in Kids with Mono
This retrospective cohort study of 52 propensity-matched children with EBV-associated infectious mononucleosis found that a TIBC cutoff of 5…
High iron levels and low platelet-to-lymphocyte ratios signal liver trouble in kids with mono before standard tests show it.
Questions about liver injury
Does the aryl hydrocarbon receptor cause liver injury through oxidative stress?
The aryl hydrocarbon receptor (AhR) can contribute to liver injury through oxidative stress, but it also protects the liver in other contexts, so its role is dual and depends on the trigger and the ligand involved [2].
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