Research across Cancer
Related studies from across the Cancer family.
HITHOC with cytoreductive surgery improves survival in pleural mesothelioma without raising early postoperative risk
Heat treatment shows survival benefit for pleural mesothelioma patients
A meta-analysis of 6 studies (n=1060) found that adding hyperthermic intrathoracic chemotherapy (HITHOC) to cytoreductive surgery for pleura…
A new analysis shows that adding heat to chemotherapy during surgery can extend life for people with a rare type of lung cancer.
Extended resection and intensity-modulated radiotherapy managed a rare primary orbit epithelioid sarcoma
Treatment approach for a rare orbit tumor in a young man
This case report describes the diagnosis and management of a 25-year-old male with primary epithelioid sarcoma of the left orbit. The patien…
A 25-year-old man with a rare eye tumor showed no signs of cancer spread after surgery and targeted radiation therapy.
Intensity-modulated radiotherapy reduces acute and delayed G2+GI toxicities versus 3D-CRT in high-risk prostate cancer
Post hoc analysis shows IMRT reduces radiation side effects for high-risk prostate cancer
This post hoc analysis of a Phase III randomized controlled trial evaluated intensity-modulated radiotherapy (IMRT) versus three-dimensional…
A post hoc analysis of a Phase III trial found that intensity-modulated radiotherapy reduced radiation side effects compared to older techni…
Tumor Treating Fields may disrupt tumor communication and induce conditional BRCAness in malignant pleural mesothelioma
New review explains how Tumor Treating Fields disrupts cancer cell networks in mesothelioma
This review explores the theoretical mechanisms of Tumor Treating Fields (TTFields) in malignant pleural mesothelioma. The authors describe …
A new review explains how Tumor Treating Fields disrupts cancer cell networks and changes the immune environment in malignant pleural mesoth…
Time to biochemical progression predicts second events in high-risk prostate cancer
Longer time to progression predicts better outcomes in prostate cancer
This phase 3 RCT of 413 men with high-risk localized prostate cancer found that a longer time from randomization to biochemical progression …
Men with high-risk prostate cancer who had a longer time before their cancer worsened were less likely to have further progression or spread…
Neoadjuvant mFOLFOXIRI plus bevacizumab reduces peritoneal tumor burden in colorectal cancer patients
Chemo before surgery may reduce tumor burden in colorectal cancer patients
This phase II randomized controlled trial evaluated 53 patients with resectable peritoneal metastasis of colorectal cancer.
A trial suggests chemo before surgery might lower tumor markers for colorectal cancer patients with spread to the abdomen.
Pembrolizumab Plus Paclitaxel Improves Survival in Recurrent Ovarian Carcinoma Compared to Paclitaxel Alone
New Drug Combo Extends Survival for Tough Ovarian Cancer
This randomised, double-blind phase 3 study evaluated pembrolizumab plus paclitaxel versus placebo plus paclitaxel in 643 female participant…
This new combination offers a meaningful survival boost for women with recurrent ovarian cancer that has become resistant to standard treatm…
Case series describes four clear cell variant papillary thyroid carcinoma cases with NCOA4-RET fusions
Rare Thyroid Cancer Has Unique Genetic Signature
This case series with literature review describes four pathologically confirmed cases of clear cell variant of papillary thyroid carcinoma d…
A rare thyroid cancer type may have a specific genetic cause that doctors can now look for.
Separate molecular profiling of mixed endometrial carcinoma components yields limited prognostic data in a small retrospective cohort
Separate tumor profiling may reveal hidden risks in mixed endometrial cancer
This hypothesis-generating retrospective cohort analysis included 8 patients with mixed endometrial carcinomas (MEEC).
In mixed endometrial cancer, testing each tumor component separately could uncover risk profiles that standard testing misses.
Pemetrexed use associated with disproportionate reporting of blood, endocrine, and renal disorders in FAERS data
Your Lung Cancer Drug May Have Side Effects Not on the Label
This pharmacovigilance study analyzed 27,098 pemetrexed-associated reports in the US FAERS database from 2004 to 2024.
A safety review of over 27,000 reports found that the lung cancer drug pemetrexed may cause side effects not currently listed on its officia…
Liquid biopsy shows high sequencing success in high-risk localized prostate cancer feasibility study
Blood Tests Replace Biopsies for Prostate Cancer
A phase 2 neoadjuvant trial in 22 patients with high-risk localized prostate cancer found liquid-based genomic profiling achieved 100% seque…
A simple blood draw now replaces painful prostate biopsies, capturing the same genetic details doctors need to pick the best treatment.
TVU during cervical screening detects 81.6% of ovarian cancers at stage I in large cohort
Can a routine ultrasound during cervical screening catch ovarian cancer early?
An observational screening study of 483,269 women undergoing cervical cancer screening found that transvaginal ultrasound performed concurre…
A routine ultrasound during cervical checks found 80% of ovarian cancers at the most curable stage in a massive Japanese screening program.