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Male breast cancer

Part of Hormone Receptor-Positive Breast Cancer

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for male breast cancer

24 trials tracked for male breast cancer.

24Trials tracked
0Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 2 20 Phase 1 1 Other / NA 3
  1. Phase 2 Combination Chemotherapy and Peripheral Blood Stem Cell Transplant Followed By Aldesleukin and Sargramostim in Treating Patients With Inflammatory Stage IIIB or Metastatic Stage IV Breast Cancer Completed
  2. Phase 2 A Phase II Study of AZD2171 in Breast Cancer Stage IV (10006202) Completed
  3. Phase 2 ONTAK® in Treating Patients With Advanced Breast Cancer That Did Not Respond to Previous Treatment Completed
  4. Phase 2 Vaccine Therapy and 1-MT in Treating Patients With Metastatic Breast Cancer Completed
  5. Phase 2 Sunitinib Malate, Paclitaxel, Doxorubicin Hydrochloride, and Cyclophosphamide Before Surgery in Treating Patients With Stage IIB-IIIC Breast Cancer Completed
  6. Phase 2 Doxorubicin Hydrochloride Liposome, Cyclophosphamide, and Trastuzumab in Treating Patients With Stage IV Breast Cancer Completed
Show 18 more trials
  1. Phase 2 Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer Completed
  2. Phase 2 GTI-2040 and Capecitabine in Treating Patients With Metastatic Breast Cancer Completed
  3. Phase 2 Topical Imiquimod and Abraxane in Treating Patients With Advanced Breast Cancer Completed
  4. Phase 2 Tipifarnib and Combination Chemotherapy in Treating Patients With Stage II or Stage III Breast Cancer Completed
  5. Phase 2 Omega-3 Fatty Acid in Treating Patients With Stage I-III Breast Cancer Completed
  6. Phase 2 Phase I-II Study of Vorinostat, Paclitaxel, and Bevacizumab in Metastatic Breast Cancer Completed
  7. Phase 2 Bevacizumab and Combination Chemotherapy in Patients With Lymph Node Positive Breast Cancer Completed
  8. Phase 2 Vaccine Therapy in Treating Patients With Stage IV Breast Cancer Completed
  9. Phase 2 Pilot Study of Paclitaxel Plus Pembrolizumab in Metastatic HER2-Negative Breast Cancer Completed
  10. Phase 2 Saracatinib in Treating Patients With Metastatic or Locally Advanced Breast Cancer That Cannot Be Removed By Surgery Completed
  11. Phase 2 Phase I-II Study of Interferon-gamma in Patients With HER-2 Positive Breast Cancer Completed
  12. Phase 2 Trastuzumab, Ixabepilone, and Carboplatin in Treating Patients With HER2/Neu-Positive Metastatic Breast Cancer Completed
  13. Phase 2 18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy Completed
  14. Phase 2 Vorinostat and Trastuzumab in Treating Patients With Metastatic or Locally Recurrent Breast Cancer Completed
  15. Phase 1 TEEL Study- Phase 1 Tamoxifen and Ribociclib (LEE011) in Advanced ER+ (HER2 Negative) Breast Cancer Completed
  16. N/A Vorinostat in Treating Patients With Stage IV Breast Cancer Receiving Hormone Therapy Completed
  17. N/A Vorinostat in Treating Patients With Stage IV Breast Cancer Receiving Aromatase Inhibitor Therapy Completed
  18. N/A Dexamethasone and Ondansetron Hydrochloride or Palonosetron Hydrochloride in Preventing Nausea and Vomiting in Patients Receiving Doxorubicin Hydrochloride and Cyclophosphamide For Early Stage Breast Cancer Completed

Showing the 24 most-cited and recently-updated of 24 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Hormone Receptor-Positive Breast Cancer

Related studies from across the Hormone Receptor-Positive Breast Cancer family.

ICIs Boost pCR in Early Triple-Negative Breast Cancer
Oncology Meta-analysis
ICIs Boost pCR in Early Triple-Negative Breast Cancer Immune drugs combined with chemotherapy improve results for triple-negative breast cancer
Adding immune checkpoint inhibitors to chemotherapy improves pathological complete response in early triple-negative breast cancer, with PD-…
Adding immune checkpoint inhibitors to chemotherapy significantly increases the chance of clearing cancer cells in triple-negative breast ca…
Platinum agents, PARP inhibitors, and immune checkpoint inhibitors increase pCR rates in early-stage TNBC
OB/GYN & Women's Health Sys. Review
Platinum agents, PARP inhibitors, and immune checkpoint inhibitors increase pCR rates in early-stage TNBC New data shows specific drug combinations improve triple-negative breast cancer outcomes
This network meta-analysis of 7,683 patients with early-stage triple-negative breast cancer (TNBC) evaluated various neoadjuvant treatment r…
New data shows that adding specific drugs like pembrolizumab or bevacizumab to standard chemotherapy can improve response rates for early-st…
Targeted therapy plus chemotherapy improves objective response and disease control rates in advanced TNBC
Oncology Meta-analysis
Targeted therapy plus chemotherapy improves objective response and disease control rates in advanced TNBC Targeted therapy plus chemotherapy improves response in triple-negative breast cancer
This systematic review and meta-analysis of 523 patients found that adding targeted therapy to chemotherapy for advanced triple-negative bre…
Adding targeted therapy to chemotherapy may improve how tumors respond in patients with advanced triple-negative breast cancer.
Adjuvant CDK4/6 inhibitors improve invasive Disease-Free Survival regardless of patient menopausal status
Oncology Meta-analysis
Adjuvant CDK4/6 inhibitors improve invasive Disease-Free Survival regardless of patient menopausal status CDK4/6 inhibitors show consistent results for both pre and postmenopausal women
This meta-analysis of 17,748 patients with HR+ and HER2-negative early breast cancer found that adjuvant CDK4/6 inhibitors improved invasive…
New data suggests that a specific type of breast cancer treatment works effectively regardless of whether a patient has reached menopause.
Neoadjuvant immune checkpoint inhibitors plus chemotherapy increase pathological complete response in early-stage triple-negative breast cancer
Allergy & Immunology Meta-analysis
Neoadjuvant immune checkpoint inhibitors plus chemotherapy increase pathological complete response in early-stage triple-negative breast cancer Immune checkpoint inhibitors improve response in triple-negative breast cancer
This meta-analysis of 3,377 patients found that neoadjuvant immune checkpoint inhibitors combined with chemotherapy significantly increased …
Adding immune checkpoint inhibitors to chemotherapy helps more patients with early-stage triple-negative breast cancer achieve a complete re…
Chemokine networks regulate triple-negative breast cancer tumor microenvironment but clinical translation remains limited
Oncology Sys. Review
Chemokine networks regulate triple-negative breast cancer tumor microenvironment but clinical translation remains limited Chemokine Targets Show Promise in Lab but Face Clinical Hurdles
This systematic review examines the role of chemokine networks and targeted interventions in the triple-negative breast cancer immune microe…
New research highlights the role of chemokine networks in breast cancer, showing strong results in labs despite challenges in current clinic…
Datopotamab deruxtecan improves progression-free survival to 10.8 months versus 5.6 months in TNBC
OB/GYN & Women's Health RCT
Datopotamab deruxtecan improves progression-free survival to 10.8 months versus 5.6 months in TNBC Trial shows datopotamab deruxtecan improves survival in triple-negative breast cancer
This Phase III randomized controlled trial of 644 patients with untreated, locally recurrent inoperable or metastatic triple-negative breast…
A new trial shows that datopotamab deruxtecan may extend progression-free and overall survival for patients with advanced triple-negative br…
Immune checkpoint inhibitors plus chemotherapy improve overall survival in advanced triple-negative breast cancer
Oncology Meta-analysis
Immune checkpoint inhibitors plus chemotherapy improve overall survival in advanced triple-negative breast cancer Immunotherapy plus chemo improves survival in triple-negative breast cancer
This umbrella meta-analysis of 39,147 patients found that combining immune checkpoint inhibitors with chemotherapy significantly improves ov…
Adding immunotherapy to chemo helps some patients with advanced triple-negative breast cancer live longer, but side effects are more common.
Multimodal fusion and radiogenomic frameworks show promise for capturing heterogeneity in triple-negative breast cancer
Oncology Sys. Review
Multimodal fusion and radiogenomic frameworks show promise for capturing heterogeneity in triple-negative breast cancer Artificial Intelligence Shows Promise in Triple-Negative Breast Cancer Care
This narrative synthesis reviews the application of artificial intelligence across radiology, digital pathology, and multi-omics for triple-…
New research shows how artificial intelligence can help identify cancer subtypes and predict treatment responses for patients with triple-ne…
Small intestinal metastasis from triple-negative breast cancer can mimic lymphoma on imaging
Oncology Sys. Review
Small intestinal metastasis from triple-negative breast cancer can mimic lymphoma on imaging Case report: Breast cancer spread to small intestine mimics lymphoma
This case report with literature review describes a patient with triple-negative breast cancer who developed small intestinal metastasis pre…
A breast cancer survivor's anemia was caused by a rare small intestine metastasis that looked like lymphoma on scans.
Datopotamab deruxtecan showed no overall survival benefit versus investigator's choice chemotherapy in metastatic HR-positive breast cancer.
OB/GYN & Women's Health RCT
Datopotamab deruxtecan showed no overall survival benefit versus investigator's choice chemotherapy in metastatic HR-positive breast cancer. Datopotamab deruxtecan extends life for advanced breast cancer patients
This Phase III randomized controlled trial evaluated datopotamab deruxtecan versus investigator's choice chemotherapy in patients with inope…
New drug datopotamab deruxtecan helps advanced breast cancer patients live longer and stay disease-free
Chemo-immunotherapy yields 12-month disease-free status in rare triple-negative neuroendocrine breast cancer
Allergy & Immunology Guideline
Chemo-immunotherapy yields 12-month disease-free status in rare triple-negative neuroendocrine breast cancer A single patient remains disease-free after a new chemo-immunotherapy approach for rare breast cancer
This case report describes a 71-year-old woman with triple-negative neuroendocrine breast cancer treated with paclitaxel, cisplatin, and pem…
A 71-year-old woman with rare breast cancer stayed disease-free for a year using a combination of chemotherapy and immunotherapy that doctor…