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Home › Conditions › MELAS syndrome

MELAS syndrome

Part of Cerebral small vessel disease

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for MELAS syndrome

2 trials tracked for MELAS syndrome: 1 in phase 3 or 4.

2Trials tracked
1Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 1 Phase 2 1
  1. Phase 4 Responses to Influenza Vaccine in Patients With Mitochondrial Disorders (MELAS) Completed
  2. Phase 2 Study of Idebenone in the Treatment of Mitochondrial Encephalopathy Lactic Acidosis & Stroke-like Episodes Completed

Showing the 2 most-cited and recently-updated of 2 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
TTI-0102 Improves Fatigue Scores in MELAS Syndrome Patients During Randomized Phase 2 Trial
Drug Pipeline RCT
TTI-0102 Improves Fatigue Scores in MELAS Syndrome Patients During Randomized Phase 2 Trial New Drug Reduces Fatigue in Rare Mitochondrial Disease
This randomized, single-blind, placebo-controlled Phase 2 trial enrolled 9 patients with MELAS syndrome caused by mtDNA m.3243A>G mutation.
This new medicine could finally give tired patients a sustainable boost in energy without the painful stomach issues that stop people from t…
medRxiv Apr 18, 2026