Genetic analyses suggest causal links between type 2 diabetes markers and cerebral small vessel disease phenotypes
High Blood Sugar May Drive Small Stroke Risk
This review synthesizes genome-wide association and Mendelian randomization data linking type 2 diabetes and glycemic indicators to cerebral…
Managing blood sugar after meals might lower your risk of a specific type of stroke.
PDE5 inhibitors increased cerebral blood flow in white matter hyperintensity regions in adults with cerebral small vessel disease.
An Old Drug Class May Protect the Brain From Silent Damage
This systematic review and meta-analysis evaluated phosphodiesterase-5 inhibitors (sildenafil or tadalafil) versus placebo in 236 adults wit…
Drugs already approved for other conditions may help restore blood flow in a part of the brain that quietly fuels strokes and dementia.
Parkinson disease associated with higher cerebral small vessel disease burden compared to healthy controls in this meta-analysis.
Parkinson's May Be a Blood Vessel Problem Too, New Review Hints
This systematic review and meta-analysis of cross-sectional studies compared adults with idiopathic Parkinson disease to healthy controls. R…
Parkinson's may be partly a disease of the brain's plumbing, not just its dopamine wiring — and that could reshape how doctors think about g…
Proteomic age acceleration linked to cerebral small vessel disease markers in US cohorts
Blood protein markers of aging linked to brain vessel disease in US community studies
An observational cohort study of US community-based participants found that higher proteomic age acceleration was associated with increased …
Higher blood protein markers of aging are linked to greater brain vessel disease and more white matter damage in US community studies.