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Home › Conditions › muscle atrophy

Muscle atrophy

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for muscle atrophy

7 trials tracked for muscle atrophy: 1 in phase 3 or 4 and 1 with published results. The most-cited published study has 24 citations.

7Trials tracked
1Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 3 1 Phase 2 3 Phase 1 1 Other / NA 2
  1. Phase 3 Testosterone Administration and ACL Reconstruction in Men Completed · 24 cited
  2. Phase 2 Electrical Stimulation for Critically Ill Post-Covid-19 Patients Completed
  3. Phase 2 Mechanistic Approach to Preventing Atrophy and Restoring Function in Older Adults Completed
  4. Phase 2 5-Alpha Reductase and Anabolic Effects of Testosterone Completed
  5. Phase 1 Electrical Stimulation for Critically Ill Covid-19 Patients Completed
  6. N/A Reducing Falls With RENEW in Older Adults Who Have Fallen Completed
Show 1 more trials
  1. N/A Mechanisms Underlying Local and Systemic Effects of Massage Completed

Showing the 7 most-cited and recently-updated of 7 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found For clinicians

Muscle atrophy: what the trials found

Clinical investigations into muscle atrophy have evaluated pharmacological and physical interventions to maintain or improve muscle mass and function. Research involving testosterone administration showed no statistically significant change in lean mass (p=0.35).

Physical modalities, specifically electrical stimulation, have been investigated as established methods for managing conditions associated with muscle loss.

Recent results — preliminary, needs further review

  • Essential Amino Acids (EAA) demonstrated statistically significant changes in MRI quadriceps and hamstring measurements (p<0.05), though these findings are not yet corroborated.
  • Testosterone Enanthate showed significant improvements in 1-RM strength, grip strength, and lumbar spine bone mineral density (p<0.05), but remains unconfirmed.
  • Massage therapy was evaluated for changes in myofiber cross-sectional area, though results remain unconfirmed.
  • The RENEW program was assessed regarding fall prevention over a one-year duration, with results currently unconfirmed.

For the clinician treating this condition

  • Testosterone administration did not result in statistically significant changes to lean mass in the studied population.
  • Electrical stimulation is an established intervention for addressing muscle atrophy concerns.

AI synthesis of 0 cited trials, updated Jun 29, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
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