Scoping review examines imatinib gonadotoxicity in males with chronic myeloid leukemia or gastrointestinal stromal tumors
Young Men's Fertility at Risk with Common Cancer Drug Imatinib
This scoping review synthesizes evidence on imatinib effects in males with chronic myeloid leukemia or gastrointestinal stromal tumors. Twen…
• Imatinib harms sperm production more in younger men permanently • Helps doctors counsel teens and young adults before treatment • Not a tr…
Case report details fatal rupture of a solitary fibrous tumor of the pleura in a trauma patient
Healthy Man Dies When Bike Crash Ruptures Hidden Chest Tumor
This case report describes a 37-year-old male who died after blunt chest trauma ruptured a giant solitary fibrous tumor of the pleura. The p…
• Giant silent chest tumors can rupture during minor trauma causing deadly bleeding • Emergency doctors spotting hidden dangers in trauma pa…
Case report describes rare coexistence of giant cell tumor and enchondroma in a 36-year-old woman
A Rare Tumor Duo Found in a Woman's Hip Bone
This case report describes a 36-year-old woman with a rare coexistence of giant cell tumor of bone and enchondroma. Histopathology revealed …
A 36-year-old woman with hip pain was found to have two distinct tumors in her pubic bone, a rare combination that highlights the need for c…
Undifferentiated Pleomorphic Sarcoma Recurrence Observed two months Postoperatively in Case Report of Gastric Mass
Cancer returns quickly after surgery and chemo for a 71-year-old woman
This case report and literature review describes a 71-year-old female with undifferentiated pleomorphic sarcoma treated with R0 resection, s…
A 71-year-old woman with rare stomach tumors had surgery and chemo, but the cancer came back just two months later.
Adjuvant Imatinib Beyond 3 Years in High-Risk GIST: 5-Year Relapse-Free Survival Outcomes
Extending Imatinib beyond 3 years did not improve survival for high-risk GIST patients
This retrospective cohort study evaluated adjuvant imatinib duration in 75 patients with high-risk GIST after radical surgery.
A look at past data shows taking Imatinib longer than three years did not help high-risk GIST patients live longer or stay cancer-free.
Meta-analysis identifies germline susceptibility loci for rare cancers including MDS and GIST
Genes linked to rare cancers found in large study of over 480,000 people
This meta-analysis of observational cohorts from over 480,000 individuals identified novel germline susceptibility loci for rare cancers.
A huge study of over 480,000 people found new genes that raise the risk of several rare cancers, offering clues for families and doctors.
Robot-assisted radiofrequency ablation reduces blood loss and hospitalization compared to open resection for osteoid osteoma
Tiny Robot, Big Pain Relief, Rare Risk
This retrospective cohort study evaluated 84 patients with osteoid osteoma comparing robot-assisted radiofrequency ablation (RFA) to open su…
A robot-assisted tool removes bone tumors with less blood loss and faster pain relief, though it takes longer and costs more than open surge…
Meta-analysis shows perioperative denosumab increases local recurrence in giant cell tumor patients
A Common Bone Tumor Drug May Raise the Risk of Cancer Coming Back
This meta-analysis evaluated perioperative denosumab in 1,551 patients undergoing surgical management of giant cell tumor.
Taking a common bone tumor drug before and after surgery nearly tripled the chance of the tumor growing back in a new analysis of 1,551 pati…
Arthroscopy-assisted curettage and bone grafting for proximal femur giant cell tumor in a 25-year-old man
Single case report suggests possible approach for treating a rare bone tumor in the hip
A case report describes a 25-year-old man with a giant cell tumor of the proximal femur who underwent arthroscopy-assisted curettage and bon…
Doctors used a small camera to remove a rare hip tumor in one patient, successfully controlling the growth while keeping the joint working n…