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Home › Conditions › Neuroinflammation

Neuroinflammation

Subtypes of Neuroinflammation

Neuroinflammatory diseases 1

5 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Luteolin suppresses neuroinflammation by modulating microglial activation and antioxidant defenses
Drug Pipeline Sys. Review
Luteolin suppresses neuroinflammation by modulating microglial activation and antioxidant defenses Luteolin Shows Promise for Brain Inflammation
This systematic review examines luteolin's effects on neuroinflammation in central nervous system disorders. The evidence suggests luteolin …
A compound in celery and parsley may help calm brain inflammation, but more research is needed.
Frontiers Jun 2, 2026
Phase 2 RCT of IV CN-105 in older adults undergoing noncardiac surgery shows fewer grade 2+ adverse events versus placebo
Drug Pipeline RCT
Phase 2 RCT of IV CN-105 in older adults undergoing noncardiac surgery shows fewer grade 2+ adverse events versus placebo Could a simple IV drug help older adults avoid confusion after surgery?
This Phase 2 randomized clinical trial enrolled 203 older adults (60 years or older) scheduled for noncardiac or nonintracranial surgery.
A new IV drug given before surgery reduced confusion and side effects in older adults, though more testing is needed to confirm it truly pre…
Apr 17, 2026
Review of ISG15 pathway targeting for inflammatory and cardiovascular diseases
Allergy & Immunology Sys. Review
Review of ISG15 pathway targeting for inflammatory and cardiovascular diseases A Tiny Protein That Fuels Your Inflammation
This narrative review examines the potential of targeting the ISG15 pathway to treat inflammatory diseases, including skin, cardiovascular, …
Understanding this protein could lead to better medicines for skin, heart, and brain diseases.
Frontiers Apr 15, 2026
Lysine lactylation links metabolism to neuroinflammation via chromatin and protein modification
Allergy & Immunology Sys. Review
Lysine lactylation links metabolism to neuroinflammation via chromatin and protein modification Review explores how a metabolic process may influence brain inflammation
A systematic review synthesizes emerging evidence that lysine lactylation (Kla) couples glycolytic state to chromatin remodeling and protein…
A metabolic process adding lactate to proteins may signal how brain cells respond to inflammation and stress in injury or disease.
Frontiers Apr 7, 2026
Review suggests TWEAK-Fn14 axis contributes to brain injury and cardiac dysfunction pathology
Cardiology Sys. Review
Review suggests TWEAK-Fn14 axis contributes to brain injury and cardiac dysfunction pathology Review explores protein link between brain and heart diseases
A systematic review summarizes evidence on the TWEAK-Fn14 signaling pathway in cardio-cerebrovascular diseases.
High levels of two specific proteins linked to brain swelling and heart scarring may offer a future target for treating brain-heart syndrome…
Frontiers Apr 2, 2026

Questions about Neuroinflammation

Will taking CN-105 reduce serious adverse events during my upcoming noncardiac operation?

A 2024 trial found that taking CN-105 before noncardiac surgery reduced serious adverse events in older adults compared to a placebo.

Full answer →
Does the TWEAK-Fn14 axis cause brain injury and heart problems in patients?

Research indicates that high levels of the TWEAK-Fn14 axis are linked to brain injury and heart problems, making it a target for treating brain-heart syndrome.

Full answer →