Research across Cardiomyopathy
Related studies from across the Cardiomyopathy family.
Black participation in hypertrophic cardiomyopathy trials is only 3.98% of the expected share
Black patients are underrepresented in heart muscle disease trials
This meta-analysis of 13 trials involving 1,780 participants identifies a significant disparity in Black representation within hypertrophic …
Black patients make up less than 4% of participants in heart muscle disease trials, despite much higher rates in the general population.
HDAC3 acts as a central epigenetic hub for Type 2 Diabetes and its complications
New research identifies a key protein linked to diabetes complications
This systematic review identifies HDAC3 as a critical regulator of immunometabolic homeostasis in Type 2 Diabetes. The review concludes that…
A specific protein called HDAC3 may play a central role in causing heart, kidney, and eye damage in people with Type 2 Diabetes.
Dystrophinopathy should be considered in adolescent males with nonischemic cardiomyopathy and heart failure
Heart failure treatment shows promise for a boy with muscular dystrophy
This case report describes a 17-year-old male with Duchenne muscular dystrophy and heart failure who showed LVEF improvement from 44% to 55%…
A 17-year-old boy with a rare muscle disease saw his heart function improve while receiving standard heart failure care.
Cardiac myosin inhibitors improve exercise capacity and health status in patients with hypertrophic cardiomyopathy
New heart medication shows promise for hypertrophic cardiomyopathy patients
This meta-analysis evaluated the impact of cardiac myosin inhibitors on adults with symptomatic non-obstructive hypertrophic cardiomyopathy.…
A new class of heart drugs may improve exercise capacity and quality of life for people with a specific heart muscle condition.
AI-empowered echocardiography shows promise for HCM diagnosis and risk prediction, but validation is lacking
AI Echocardiography Shows Promise for Heart Condition
This systematic review synthesizes AI-empowered echocardiography applications in hypertrophic cardiomyopathy, categorizing methods by comple…
AI-powered echocardiography may improve diagnosis and risk prediction for hypertrophic cardiomyopathy, but large-scale validation is still n…
Transthyretin stabilizers and RNA-silencing therapies attenuate cardiac remodeling in transthyretin amyloid cardiomyopathy
New Therapies May Slow Heart Damage in Amyloid Cardiomyopathy
This meta-analysis of 3646 adults with cardiac amyloidosis found that transthyretin stabilizers and RNA-silencing therapies are associated w…
Specific drug therapies may help stabilize heart structure and slow the progression of damage for adults with transthyretin amyloid cardiomy…
Gene, inflammation, and metabolic dysregulation drive pathophysiology in pediatric dilated cardiomyopathy
Gene, Inflammation, Metabolism Link in Child Heart Failure
This systematic review examines the role of the gene-inflammation-metabolism axis in pediatric dilated cardiomyopathy. The authors identify …
A new review links genes, inflammation, and metabolism in pediatric dilated cardiomyopathy, offering a roadmap for targeted treatments.
Supraventricular tachyarrhythmias occur more frequently in patients with Arrhythmogenic Cardiomyopathy and Brugada Syndrome
Heart conditions like Brugada syndrome increase risk of rapid heartbeats
This systematic review of 30 studies indicates that supraventricular tachyarrhythmias (SVT) are more frequent in patients with Arrhythmogeni…
Patients with certain heart conditions face a higher risk of fast heartbeats, which can lead to complications like heart failure or unnecess…
Exercise improves cardiorespiratory fitness and quality of life in patients with hypertrophic cardiomyopathy
Exercise improves heart health and fitness for HCM patients
This meta-analysis of 9,702 patients with hypertrophic cardiomyopathy (HCM) found that exercise is associated with increased peak oxygen con…
New research shows that structured exercise can improve heart fitness, body weight, and quality of life for people with hypertrophic cardiom…
Global Longitudinal Strain as a Potential Predictor of Sudden Cardiac Death in Hypertrophic Cardiomyopathy
Heart imaging helps identify high risk in cardiomyopathy patients
Meta-analysis suggests reduced global longitudinal strain identifies high-risk patients with hypertrophic cardiomyopathy prone to fatal arrh…
A new way to measure heart muscle movement may help doctors identify which patients with a specific heart condition are at higher risk for s…
Vascular smooth muscle cell immune interactions drive remodeling across cardiovascular diseases
How blood vessel cells drive heart disease and high blood pressure
This narrative review synthesizes mechanisms of VSMC-immune interactions in atherosclerosis, hypertension, aortic aneurysms, and arteritis. …
A new review reveals how blood vessel cells change in heart disease, high blood pressure, and more.
Review of Diabetic Cardiomyopathy without reported trial data or specific outcomes
Review of Diabetic Cardiomyopathy offers new understanding of this heart condition
This narrative review addresses Diabetic cardiomyopathy but reports no specific population, sample size, or intervention details. The author…
This review looks at diabetic cardiomyopathy to help doctors understand this specific heart problem better for patients with diabetes.