Mode
Text Size
Log in / Sign up

Papillary Thyroid Cancer

Part of Head and Neck Cancer

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Papillary Thyroid Cancer

6 trials tracked for Papillary Thyroid Cancer.

6Trials tracked
0Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 2 4 Phase 1 1 Other / NA 1
  1. Phase 2 Dabrafenib With or Without Trametinib in Treating Patients With Advanced Differentiated Thyroid Cancer Completed
  2. Phase 2 Sutent Adjunctive Treatment of Differentiated Thyroid Cancer Completed
  3. Phase 2 Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors Completed
  4. Phase 2 Sorafenib Tosylate in Treating Younger Patients With Relapsed or Refractory Rhabdomyosarcoma, Wilms Tumor, Liver Cancer, or Thyroid Cancer Completed
  5. Phase 1 Vemurafenib Plus Copanlisib in Radioiodine-Refractory (RAIR) Thyroid Cancers Completed
  6. N/A Treatment of Papillary Thyroid Carcinoma With Radiofrequency Ablation Completed

Showing the 6 most-cited and recently-updated of 6 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Head and Neck Cancer

Related studies from across the Head and Neck Cancer family.

Preoperatively detected PTEN alterations in thyroid nodules correlate with a 32.4% risk of invasive malignancy
ENT (Otolaryngology) Meta-analysis
Preoperatively detected PTEN alterations in thyroid nodules correlate with a 32.4% risk of invasive malignancy Molecular testing helps identify risk in thyroid nodules
This meta-analysis of 87 patients with Bethesda III/IV thyroid nodules identifies a 32.4% risk of invasive malignancy in those with preopera…
New molecular testing can help doctors identify the risk of cancer in thyroid nodules, providing a clearer picture for patients with uncerta…
Gut Microbiome and Metabolites May Modulate Thyroid Cancer Immunity and Treatment Response
Oncology Sys. Review
Gut Microbiome and Metabolites May Modulate Thyroid Cancer Immunity and Treatment Response Gut bacteria and metabolites may influence thyroid cancer treatment
This narrative review examines how gut dysbiosis, bacterial outer membrane components such as lipopolysaccharides, and metabolites including…
Your gut health might play a hidden role in how your body responds to thyroid cancer treatments and immune system interactions.
CEUS combined with AI or elastography improves diagnostic performance for malignant thyroid nodules
Diabetes & Endocrinology Meta-analysis
CEUS combined with AI or elastography improves diagnostic performance for malignant thyroid nodules Contrast-Enhanced Ultrasound Shows Promise for Identifying Thyroid Nodules
This network meta-analysis of 5022 thyroid nodules evaluated the diagnostic performance of contrast-enhanced ultrasound (CEUS) combined with…
New analysis shows that combining contrast-enhanced ultrasound with other imaging tools can help doctors better identify malignant thyroid n…
Sociodemographic, laboratory, and ultrasonographic factors are associated with malignancy risk in thyroid nodules
Diabetes & Endocrinology Meta-analysis
Sociodemographic, laboratory, and ultrasonographic factors are associated with malignancy risk in thyroid nodules Specific Factors Linked to Higher Risk in Thyroid Nodules
This systematic review and meta-analysis of 194 studies evaluated sociodemographic, laboratory, and ultrasound features to assess malignancy…
Certain factors like male sex and specific ultrasound features are linked to a higher risk of cancer in patients with thyroid nodules.
Plectin knockdown and troglitazone treatment inhibit growth and migration in papillary thyroid carcinoma cell lines
Allergy & Immunology Guideline
Plectin knockdown and troglitazone treatment inhibit growth and migration in papillary thyroid carcinoma cell lines Plectin and Troglitazone Show Promise in Thyroid Cancer
This guideline synthesizes preclinical data regarding plectin (PLEC) as a potential target in papillary thyroid carcinoma. The findings sugg…
Researchers found that plectin is elevated in papillary thyroid cancer and that troglitazone may fight it by targeting plectin.
Intraoperative frozen section shows 98.8% specificity but limited sensitivity for detecting malignancy in Bethesda III nodules
ENT (Otolaryngology) Sys. Review
Intraoperative frozen section shows 98.8% specificity but limited sensitivity for detecting malignancy in Bethesda III nodules Frozen Section Analysis Shows High Specificity for Thyroid Nodules
This systematic review and meta-analysis of 1,069 patients with thyroid nodules evaluates the diagnostic accuracy of intraoperative frozen s…
Intraoperative frozen section tests show high accuracy in identifying cancer in certain thyroid nodules, but results can vary significantly.
No established correlation exists between paragangliomas and cervical lymph node metastasis in papillary thyroid carcinoma
Oncology Sys. Review
No established correlation exists between paragangliomas and cervical lymph node metastasis in papillary thyroid carcinoma Distinguishing Between Thyroid Cancer and Paraganglioma for Better Diagnosis
This case report and literature review examines the relationship between paragangliomas and cervical lymph node metastasis in patients with …
Doctors must accurately distinguish between thyroid cancer and paragangliomas to ensure correct treatment plans and accurate patient prognos…
FNA-Tg and BRAF V600E analysis can rectify histopathological misdiagnosis of cervical lymph node metastasis
Orthopedics & Sports Medicine Meta-analysis
FNA-Tg and BRAF V600E analysis can rectify histopathological misdiagnosis of cervical lymph node metastasis Combined Testing Corrects Diagnosis of Thyroid Cancer Lymph Node Spread
This case report describes a 52-year-old female with papillary thyroid carcinoma where combined FNA-Tg and BRAF V600E analysis corrected a h…
A new testing method using FNA-Tg and BRAF V600E analysis helped correctly identify cancer spread in a patient with thyroid cancer.
Contrast-enhanced ultrasound shows 81.6% diagnostic accuracy for differentiating benign from malignant thyroid nodules
Diabetes & Endocrinology Meta-analysis
Contrast-enhanced ultrasound shows 81.6% diagnostic accuracy for differentiating benign from malignant thyroid nodules Contrast-enhanced ultrasound shows promise for thyroid nodule diagnosis
This meta-analysis of 54 CEUS studies evaluated the diagnostic performance of contrast-enhanced ultrasound for characterizing thyroid nodule…
A new analysis finds contrast-enhanced ultrasound is 78.6% sensitive and 82.6% specific for telling benign from malignant thyroid nodules.
Case report review highlights suspicion of breast cancer metastasis to thyroid in a 54-year-old woman
Orthopedics & Sports Medicine Sys. Review
Case report review highlights suspicion of breast cancer metastasis to thyroid in a 54-year-old woman Breast cancer can spread to the thyroid gland in rare cases
This case report review describes a 54-year-old woman with a history of breast cancer who developed metastasis to the thyroid. The authors n…
A single case report shows a 54-year-old woman survived after breast cancer spread to her thyroid, highlighting the need for careful diagnos…
Case report and review: IVIg and efgartigimod in Guillain-Barré with Graves disease and thyroid cancer
Allergy & Immunology Sys. Review
Case report and review: IVIg and efgartigimod in Guillain-Barré with Graves disease and thyroid cancer Doctors treat a rare relapse of Guillain-Barré syndrome with new immune therapies
This case report and literature review describes a 33-year-old man with Guillain-Barré syndrome, Graves disease, and papillary thyroid carci…
A 33-year-old man with Guillain-Barré syndrome found relief after doctors treated his underlying thyroid cancer and used new immune therapie…
Review of 32 cases of thyroid hemiagenesis with carcinoma highlights surgical and diagnostic patterns
Diabetes & Endocrinology Sys. Review
Review of 32 cases of thyroid hemiagenesis with carcinoma highlights surgical and diagnostic patterns Doctors found rare thyroid cancer cases in patients with one missing half of their gland
This review and case series of 32 patients with thyroid hemiagenesis complicated by thyroid carcinoma synthesized diagnostic and treatment p…
A review of thirty-two patients shows that having half a thyroid gland does not stop cancer from forming. Most cases were treated with surge…