miR-155 overexpression is frequently associated with treatment resistance across 8 cancer types
miR-155 Expression Linked to Treatment Resistance in Various Cancers
This systematic review of 19 studies across 8 cancer types indicates that miR-155 overexpression is associated with treatment resistance in …
Research suggests that high levels of a specific molecule, miR-155, may be linked to how well certain cancers respond to treatment.
Hashimoto's thyroiditis is a risk factor for papillary thyroid cancer with associated improved outcomes
Hashimoto's thyroiditis linked to both cancer risk and better outcomes
This narrative review examines the relationship between Hashimoto's thyroiditis (HT) and papillary thyroid cancer (PTC). The authors suggest…
A growing body of evidence shows that while Hashimoto's thyroiditis can increase cancer risk, it may also be linked to better outcomes for p…
Machine learning algorithm predicts skip metastasis in papillary thyroid cancer in retrospective cohort
Can a computer help spot tricky thyroid cancer spread?
A retrospective, single-center cohort study of 361 patients undergoing thyroidectomy with lymph node dissections developed a machine learnin…
A computer program can spot tricky thyroid cancer spread that jumps over nearby nodes, helping surgeons plan more effective operations befor…
Research across Head and Neck Cancer
Related studies from across the Head and Neck Cancer family.
Hashimoto's thyroiditis functions as a dual-natured immune microenvironment in differentiated thyroid cancer
Hashimoto's thyroiditis may both help and hinder thyroid cancer
This narrative review explores the role of Hashimoto's thyroiditis (HT) in the immune microenvironment of differentiated thyroid cancer. The…
Hashimoto's thyroiditis can act as both a shield and a sword for thyroid cancer, depending on the specific immune environment of the patient…
Molecular testing reduces surgical resection rates for indeterminate thyroid nodules in Western and Asian cohorts
Molecular testing helps decide if surgery is needed for thyroid nodules
This meta-analysis of 127 studies evaluated the impact of molecular testing on surgical management and risk of malignancy for indeterminate …
Molecular testing can help doctors decide if surgery is necessary for thyroid nodules, showing different clinical roles in Western and Asian…
Vitamin D and gut microbiota interact to regulate immunity and improve bioavailability in thyroid disorders
Vitamin D and gut health may help manage thyroid disorders
This systematic review explores the interplay between Vitamin D and gut microbiota in patients with thyroid disorders, including autoimmune …
New research highlights how vitamin D and gut bacteria work together to support the immune system in people with thyroid conditions.
Preoperatively detected PTEN alterations in thyroid nodules correlate with a 32.4% risk of invasive malignancy
Molecular testing helps identify risk in thyroid nodules
This meta-analysis of 87 patients with Bethesda III/IV thyroid nodules identifies a 32.4% risk of invasive malignancy in those with preopera…
New molecular testing can help doctors identify the risk of cancer in thyroid nodules, providing a clearer picture for patients with uncerta…
Gut Microbiome and Metabolites May Modulate Thyroid Cancer Immunity and Treatment Response
Gut bacteria and metabolites may influence thyroid cancer treatment
This narrative review examines how gut dysbiosis, bacterial outer membrane components such as lipopolysaccharides, and metabolites including…
Your gut health might play a hidden role in how your body responds to thyroid cancer treatments and immune system interactions.
CEUS combined with AI or elastography improves diagnostic performance for malignant thyroid nodules
Contrast-Enhanced Ultrasound Shows Promise for Identifying Thyroid Nodules
This network meta-analysis of 5022 thyroid nodules evaluated the diagnostic performance of contrast-enhanced ultrasound (CEUS) combined with…
New analysis shows that combining contrast-enhanced ultrasound with other imaging tools can help doctors better identify malignant thyroid n…
Sociodemographic, laboratory, and ultrasonographic factors are associated with malignancy risk in thyroid nodules
Specific Factors Linked to Higher Risk in Thyroid Nodules
This systematic review and meta-analysis of 194 studies evaluated sociodemographic, laboratory, and ultrasound features to assess malignancy…
Certain factors like male sex and specific ultrasound features are linked to a higher risk of cancer in patients with thyroid nodules.
Plectin knockdown and troglitazone treatment inhibit growth and migration in papillary thyroid carcinoma cell lines
Plectin and Troglitazone Show Promise in Thyroid Cancer
This guideline synthesizes preclinical data regarding plectin (PLEC) as a potential target in papillary thyroid carcinoma. The findings sugg…
Researchers found that plectin is elevated in papillary thyroid cancer and that troglitazone may fight it by targeting plectin.
Intraoperative frozen section shows 98.8% specificity but limited sensitivity for detecting malignancy in Bethesda III nodules
Frozen Section Analysis Shows High Specificity for Thyroid Nodules
This systematic review and meta-analysis of 1,069 patients with thyroid nodules evaluates the diagnostic accuracy of intraoperative frozen s…
Intraoperative frozen section tests show high accuracy in identifying cancer in certain thyroid nodules, but results can vary significantly.
No established correlation exists between paragangliomas and cervical lymph node metastasis in papillary thyroid carcinoma
Distinguishing Between Thyroid Cancer and Paraganglioma for Better Diagnosis
This case report and literature review examines the relationship between paragangliomas and cervical lymph node metastasis in patients with …
Doctors must accurately distinguish between thyroid cancer and paragangliomas to ensure correct treatment plans and accurate patient prognos…
FNA-Tg and BRAF V600E analysis can rectify histopathological misdiagnosis of cervical lymph node metastasis
Combined Testing Corrects Diagnosis of Thyroid Cancer Lymph Node Spread
This case report describes a 52-year-old female with papillary thyroid carcinoma where combined FNA-Tg and BRAF V600E analysis corrected a h…
A new testing method using FNA-Tg and BRAF V600E analysis helped correctly identify cancer spread in a patient with thyroid cancer.
Contrast-enhanced ultrasound shows 81.6% diagnostic accuracy for differentiating benign from malignant thyroid nodules
Contrast-enhanced ultrasound shows promise for thyroid nodule diagnosis
This meta-analysis of 54 CEUS studies evaluated the diagnostic performance of contrast-enhanced ultrasound for characterizing thyroid nodule…
A new analysis finds contrast-enhanced ultrasound is 78.6% sensitive and 82.6% specific for telling benign from malignant thyroid nodules.