Research across Parkinson's Disease
Related studies from across the Parkinson's Disease family.
Citicoline increases likelihood of achieving minimal clinically important difference in Parkinson's disease by OR 2.06
Trial shows citicoline may improve movement in Parkinson's disease
This randomized, double-blind, multicenter trial of 485 patients with Parkinson's disease found that citicoline (1000 mg/day intramuscular) …
A new trial suggests that adding citicoline to standard medication may improve motor function and quality of life for people with Parkinson'…
Neurofeedback shows potential for motor and non-motor outcomes in idiopathic Parkinson's disease
New neurofeedback methods show potential for Parkinson's disease patients
This narrative review explores the neurophysiological feasibility and clinical effects of EEG-based, fMRI-based, and DBS-guided neurofeedbac…
New research explores how brain-training techniques like neurofeedback might help people with Parkinson's manage movement and motor symptoms…
Robot-assisted gait training improves balance, walking endurance, and spatiotemporal gait parameters in Parkinson's disease
Robot-Assisted Gait Training Shows Promise for Parkinson's Mobility
This meta-analysis evaluates the efficacy of robot-assisted gait training (RAGT) compared to conventional rehabilitation and other intervent…
Robot-assisted gait training may improve balance and walking endurance for people with Parkinson's disease compared to standard rehabilitati…
DEK emerges as neuron-specific ac4C-linked driver of neuroinflammation in Parkinson's disease
New research identifies a specific gene linked to Parkinson's disease
This multi-omics analysis with in vitro validation identifies 7 ac4C-associated risk genes in Parkinson's disease and stratifies patients in…
Researchers identified a specific gene and a potential new drug target to help manage inflammation in Parkinson's disease.
Wearable digital biomarkers show potential for neurorehabilitation monitoring, but evidence is heterogeneous and early
Wearable devices track movement and health for neurological recovery
This scoping review of 56 studies synthesizes evidence on wearable-derived digital biomarkers in neurological rehabilitation, focusing on st…
Wearable sensors can track movement and physical signs to help people recovering from stroke, Parkinson disease, and spinal cord injuries.
TLE4, HLA-V/HLA-G, and LRRK2 variants show significant association with Parkinson's disease in East Asian cohorts
Genetic Variants Linked to Parkinson's Disease in East Asian Populations
This meta-analysis of genetic variants in East Asian individuals identifies TLE4, HLA-V/HLA-G, and LRRK2 as significant risk factors for Par…
New research identifies specific genetic variants linked to Parkinson's disease in East Asian populations, highlighting how ancestry affects…
IL-34/CSF1R signaling modulates CNS immune cell development and impacts neurodegenerative disease progression
IL-34 Signaling Pathway Shows Complex Role in Brain Disorders
This systematic review examines the role of the IL-34/CSF1R signaling axis in CNS-resident immune cells and its impact on neurological disor…
A specific signaling pathway may play a dual role in brain health, potentially protecting nerves or contributing to diseases like Alzheimer'…
Tai Chi provides positive effects for balance, mood, and cognitive performance in older adults
Tai Chi Shows Positive Effects for Older Adults with Parkinson's
This evidence map synthesized 118 systematic reviews regarding Tai Chi for older adults. The findings indicate positive effects for balance,…
Tai Chi may help older adults improve balance, reduce anxiety, and manage symptoms of Parkinson's disease and other age-related conditions.
Twelve SNPs associated with Parkinson's disease-related gray matter volume reduction were identified in meta-analysis
Genetic variants linked to brain tissue loss in Parkinson's disease
This meta-analysis of 3212 patients with Parkinson's disease and 2056 controls identifies robust patterns of gray matter volume reduction an…
New research identifies specific genetic markers and brain tissue loss patterns in Parkinson's disease to help find future treatment targets…
Augmented fixation and soft-tissue reinforcement may address patellar fracture nonunion in patients with Parkinson's disease
Surgical Techniques for Patellar Fractures in Parkinson's Disease Patients
This case report and focused literature review describes a patient with Parkinson's disease who underwent revision surgery for a patellar fr…
A case report explores how surgeons manage complex knee fractures in patients with Parkinson's disease to improve mobility and manage pain.
Invasive spinal cord stimulation provides variable relief across diverse chronic neuropathic pain conditions
Different types of spinal cord stimulation help various chronic pains
This narrative review synthesizes evidence on invasive spinal cord stimulation (SCS) for various neurological and pain conditions. The autho…
Newer forms of spinal cord stimulation offer promising relief for complex nerve pain and failed back surgeries, but results vary by conditio…
tACS shows no significant motor benefit in Parkinson's disease, meta-analysis finds
Trial Shows No Significant Improvement in Parkinson's With tACS
This meta-analysis of small trials found no statistically significant difference between transcranial alternating current stimulation (tACS)…
A review of clinical data suggests that transcranial alternating current stimulation does not currently improve motor symptoms for people wi…