Narrative review suggests music therapy may improve cognition and neuropsychiatric symptoms in cognitive impairment
Music therapy may help minds affected by Alzheimer's and other cognitive conditions
This narrative review examines the role of music therapy for cognitive impairment. The authors suggest that music therapy may improve cognit…
Music therapy might improve thinking and mood for people with Alzheimer's disease, mild cognitive impairment, or Parkinson's-related cogniti…
Cohort study compares homocysteine and uric acid levels in Parkinson's disease-related and post-stroke cognitive impairment
Parkinson's patients show unique blood markers that differ from stroke survivors
This cohort study included 120 patients with cognitive impairment admitted to the Department of Neurology at Yangjiang Hospital of Tradition…
New blood tests reveal unique chemical differences between Parkinson's and stroke patients, offering a clearer path to accurate diagnosis.
Research across Parkinson's Disease
Related studies from across the Parkinson's Disease family.
Evaluating the Impact of Digital Health Interventions on Chronic Disease Self-Care Outcomes
Digital health tools show mixed results for managing chronic diseases
Digital tools show promise for heart failure monitoring but lack consistent evidence for improving medication adherence or general diabetes …
New data shows that while digital tools like apps can help heart failure patients monitor their health, they may not improve medication habi…
Exercise, microbiota, and tRNA modifications may influence mitochondrial function and proteostasis in Parkinson's disease
Exercise and gut health may protect brain cells in Parkinson's
This narrative review explores the exercise-microbiota-queuine-tRNA axis as a potential mechanism for dopaminergic neuroprotection in Parkin…
New research explores how exercise, gut bacteria, and RNA modifications might work together to protect the brain from Parkinson's disease.
Current non-motor symptom classifications fail Parkinson's complexity, review finds
Parkinson's symptom classification fails patients, review finds
This narrative review critiques current symptom-based classification systems for non-motor symptoms (NMS) in Parkinson's disease, finding th…
Current systems for grouping Parkinson's non-motor symptoms miss their complexity, a new review reveals.
Bipolar disorder is associated with a 3.65-fold higher risk of Parkinson's disease in six cohort studies
People with bipolar disorder face higher risk of developing Parkinson's disease based on recent analysis
This meta-analysis of six cohort studies evaluated the incidence of Parkinson's disease in individuals with bipolar disorder. The pooled ana…
A review of six studies found people with bipolar disorder have a much higher chance of getting Parkinson's disease. However, experts say we…
HMC3 microglial model illuminates neurodegenerative mechanisms and early therapeutic discovery
New tool helps scientists study brain cell stress in Alzheimer's and Parkinson's disease
This narrative review synthesizes experimental evidence from HMC3 human microglial cell line and co-culture systems to explore mechanisms in…
Scientists use a special human brain cell line to study stress and cell death in diseases like Alzheimer's and Parkinson's, offering a new w…
Six novel loci and nine recessive loci identified for young onset Parkinson's disease in European ancestry
Genetic clues to young onset Parkinson's disease found in large global study
This meta-analysis of genome-wide association studies in 1,528 patients and 20,408 controls identified six independent loci and nine recessi…
A massive analysis of genetic data found six new spots in our DNA linked to early Parkinson's disease, offering hope for better prevention a…
Nutrient and metabolite interventions for neurodegenerative diseases show inconsistent clinical translation
Dietary nutrients show mixed results for brain diseases in lab and early human data
This narrative review synthesizes evidence on nutrients and metabolites for Alzheimer's, Parkinson's, multiple sclerosis, and amyotrophic la…
Nutrients like vitamins and marine compounds show promise in labs, but human evidence for brain diseases remains inconsistent and unclear.
QSM MRI reveals distinct iron deposition patterns differentiating Parkinsonian syndromes
Brain MRI technique may help tell apart Parkinson's and similar disorders
This systematic review and meta-analysis of 626 PD, 160 MSA, 176 PSP patients and 256 controls found that quantitative susceptibility mappin…
A special MRI can spot distinct brain iron patterns in Parkinson's and related diseases, offering a potential diagnostic tool.
Continuous subcutaneous foslevodopa/foscarbidopa improves off time in Parkinson's disease; severe adverse events higher in prior DBS group
Patients with Parkinsons disease who had prior brain surgery saw more side effects while using new skin patches
This post hoc analysis of an open-label phase 3 trial evaluated continuous subcutaneous infusion of foslevodopa/foscarbidopa in 244 patients…
A new look at trial data shows skin patches help Parkinsons patients move better and sleep longer. However, those who had brain surgery earl…
GBA1 L444P carriers have ninefold higher odds of Parkinson's disease than non-carriers
People with one GBA1 L444P gene change face much higher risk of developing Parkinson's disease compared to those without it
This systematic review and meta-analysis of 33,752 PD patients and 34,101 controls found that heterozygous GBA1 L444P carriers had markedly …
A large review of over sixty-seven thousand people found that carrying one copy of the GBA1 L444P gene change greatly increases the chance o…
Prasinezumab showed non-significant delay in motor progression versus placebo in early-stage Parkinson's disease
Early Parkinson's drug trial shows no delay in motor progression
This phase 2b trial evaluated intravenous prasinezumab in individuals with early-stage Parkinson's disease on stable medication. The study f…
A Phase 2b trial of prasinezumab in early Parkinson's disease failed to meet its primary endpoint of delaying motor progression compared to …
Review synthesizes neuroprotective potential of TCM metabolites using zebrafish models for neurological conditions
Traditional Chinese medicine metabolites protect brain cells from damage
This review examines the utility of Traditional Chinese medicine (TCM) metabolites for neurological conditions including Alzheimer's disease…
A review shows Traditional Chinese medicine metabolites protect brain cells through anti-inflammatory and anti-oxidative stress actions, off…