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Prodromal Parkinson's disease

Part of Parkinson's Disease

1 published article · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Parkinson's Disease

Related studies from across the Parkinson's Disease family.

GLP-1 receptor agonists are an emerging research focus for metabolic and inflammatory pathways in Parkinson's disease
Neurology Meta-analysis
GLP-1 receptor agonists are an emerging research focus for metabolic and inflammatory pathways in Parkinson's disease GLP-1 receptor agonists show promise for Parkinson's disease research
This bibliometric analysis of 282 articles identifies GLP-1 receptor agonists as a growing research area for Parkinson's disease. Key themes…
New research highlights how GLP-1 medications, often used for metabolic issues, are becoming a major focus in treating Parkinson's disease.
α-Synuclein-lysosome axis central to Parkinson's pathogenesis, systematic review finds
Neurology Sys. Review
α-Synuclein-lysosome axis central to Parkinson's pathogenesis, systematic review finds Parkinson's protein and lysosome link may guide new treatments
This systematic review synthesizes molecular evidence that the interplay between α-synuclein and lysosomal function is a central mechanism u…
A review reveals how a protein called α-synuclein and lysosomes interact in Parkinson's, pointing to potential new therapies.
Dynamic gratings serve as tools for diagnosis and treatment evaluation in neuro-ophthalmic conditions
Ophthalmology Sys. Review
Dynamic gratings serve as tools for diagnosis and treatment evaluation in neuro-ophthalmic conditions Dynamic gratings help doctors understand and treat eye conditions
This narrative review explores the use of dynamic gratings, such as phase-alternating oscillation and rapid serial visual presentation, to e…
Moving patterns on a screen, called dynamic gratings, offer new ways to study and treat vision issues like glaucoma and diabetic retinopathy…
Reduced Vagus Nerve Cross Sectional Area as a Potential Biomarker in Parkinson Disease
Neurology Meta-analysis
Reduced Vagus Nerve Cross Sectional Area as a Potential Biomarker in Parkinson Disease Smaller vagus nerve size linked to Parkinson's disease
Meta-analysis reveals significant reductions in the cross-sectional area of the vagus nerve in patients with Parkinson's disease compared to…
A large review of medical data shows that the vagus nerve is smaller in people with Parkinson's disease, potentially offering a new way to t…
Botulinum toxin type A effectively manages sialorrhea in pediatric and adult neurological disorders
Neurology Sys. Review
Botulinum toxin type A effectively manages sialorrhea in pediatric and adult neurological disorders Botulinum toxin helps manage drooling in neurological conditions
This narrative review examines the use of botulinum toxin type A for managing sialorrhea in patients with cerebral palsy and Parkinson's dis…
Newer insights show how botulinum toxin can help children and adults with neurological disorders manage excessive drooling.
TCMQE exercises including Baduanjin, Qigong, and Tai Chi improve motor symptoms and balance in Parkinson's disease
Neurology Meta-analysis
TCMQE exercises including Baduanjin, Qigong, and Tai Chi improve motor symptoms and balance in Parkinson's disease Traditional Chinese medicine exercises may improve Parkinson's disease symptoms
This network meta-analysis of 59 RCTs involving 3,743 patients evaluated various traditional Chinese medicine qigong exercise (TCMQE) modali…
Specific traditional Chinese medicine exercises like Tai Chi and Baduanjin show promise in improving balance, movement, and mood for those w…
Evaluating the Efficacy of GLP-1 Receptor Agonists in Patients with Parkinson's Disease
Neurology Meta-analysis
Evaluating the Efficacy of GLP-1 Receptor Agonists in Patients with Parkinson's Disease GLP-1 medications show no motor benefit for Parkinson's patients
A meta-analysis reveals that GLP-1 receptor agonists provide no significant motor or non-motor benefits for patients with idiopathic Parkins…
New data suggests GLP-1 receptor agonists do not improve movement or non-motor symptoms in people with Parkinson's disease.
Adaptive immune signatures and T cell infiltration characterize pathology in Alzheimer's, Parkinson's, and Lewy Body dementia
Neurology Sys. Review
Adaptive immune signatures and T cell infiltration characterize pathology in Alzheimer's, Parkinson's, and Lewy Body dementia Adaptive Immune Signatures Linked to Alzheimer's and Parkinson's Disease
This mini review synthesizes evidence regarding adaptive immune remodeling and T cell responses in neurodegenerative dementias. The authors …
New research highlights how specific immune cell activity may play a role in the progression of Alzheimer's, Parkinson's, and Lewy body deme…
Mammillothalamic tract serves as a reliable anatomical landmark for MRgFUS PTT planning in Parkinson's disease
Radiology & Imaging Sys. Review
Mammillothalamic tract serves as a reliable anatomical landmark for MRgFUS PTT planning in Parkinson's disease New MRI landmarks help target Parkinson's disease treatments more accurately
This mini review evaluates MRI techniques for locating pallidothalamic pathways during MRgFUS PTT planning. It concludes that the mammilloth…
Doctors are using a specific brain structure as a reliable landmark to improve the accuracy of targeting Parkinson's disease during treatmen…
rTMS improves motor function in Parkinson's disease, meta-analysis finds moderate effect
Neurology Meta-analysis
rTMS improves motor function in Parkinson's disease, meta-analysis finds moderate effect Magnetic brain stimulation improves movement in Parkinson's disease patients
This meta-analysis of 457 patients found that repetitive transcranial magnetic stimulation (rTMS) significantly reduces UPDRS-III scores com…
A new review shows that magnetic brain stimulation can improve motor functions and movements for people living with Parkinson's disease.
GLP-1 receptor agonists improve motor function and mood outcomes in patients with Parkinson's disease
Neurology Meta-analysis
GLP-1 receptor agonists improve motor function and mood outcomes in patients with Parkinson's disease GLP-1 medications show promise for Parkinson's disease motor symptoms
This meta-analysis of 850 patients found that GLP-1 receptor agonists significantly improved motor function (SMD -0.21 to -0.32) and mood ou…
New data suggests certain GLP-1 medications may improve movement and mood in people living with Parkinson's disease.
Loon Lens outperforms Catchii for title and abstract screening in Parkinson Disease research
Neurology Sys. Review
Loon Lens outperforms Catchii for title and abstract screening in Parkinson Disease research Agentic AI Tools Show Promise for Screening Parkinson Disease Research
This systematic review evaluates the performance of agentic AI tools, specifically Loon Lens and Catchii, for screening titles and abstracts…
New research shows that specific AI tools can help researchers identify relevant studies on Parkinson disease more accurately than other aut…