Research across Hypertension
Related studies from across the Hypertension family.
Nocturnal hypertension affects 42.5% of population samples, isolated nocturnal hypertension 17.3%
High blood pressure during sleep is common in many people
This meta-analysis estimates the prevalence of nocturnal hypertension and isolated nocturnal hypertension in population-based and community …
Nearly half of people with high blood pressure experience it specifically at night, a finding that helps doctors plan better screening tools…
Study-defined hypertension is not a statistically significant predictor of recurrence in intracranial aneurysms
High blood pressure may not predict aneurysm recurrence after treatment
This systematic review and meta-analysis of 2,442 observations from 8 studies found no statistically significant association between study-d…
New data suggests that a history of high blood pressure does not clearly predict if an aneurysm will return after surgery.
Short-chain fatty acids and intestinal macrophages modulate metabolism in metabolic syndrome and obesity
Short Chain Fatty Acids May Help Manage Metabolic Syndrome
This narrative review explores how short-chain fatty acids (SCFAs) like butyrate, acetate, and propionate influence intestinal macrophage im…
Short-chain fatty acids like butyrate may influence how the body handles inflammation and metabolism in people with obesity and insulin resi…
Gut microbiome dysbiosis may contribute to cognitive decline through neuroinflammation and hypertension-mediated cerebrovascular injury
Gut health and blood pressure may impact brain health
This narrative review explores the gut-brain-vascular axis, proposing that gut microbiome dysbiosis contributes to cognitive decline via neu…
New research explores how an unbalanced gut and high blood pressure might work together to cause brain aging and cognitive decline.
RAAS inhibitors modulate inflammatory responses and oxidative stress across multiple chronic conditions
RAAS Inhibitors May Protect Organs Beyond Lowering Blood Pressure
This systematic review synthesizes the roles of ACEI, ARB, DRI, ARNI, and MRA in modulating inflammatory responses and oxidative stress. The…
New research suggests certain blood pressure medications may protect the heart, kidneys, and lungs by reducing inflammation and oxidative st…
Aerobic Training Lowers Blood Pressure in Hypertension Across 26 Studies
Aerobic training shows significant blood pressure drops for adults
This meta-analysis of 26 studies (1,576 adults with hypertension) found that aerobic training produced statistically significant and clinica…
Aerobic exercise provides meaningful reductions in both systolic and diastolic blood pressure for adults living with hypertension.
KLF1 variants identified in neonate with severe hemolytic anemia and pulmonary hypertension
Genetic testing helps identify a rare cause of severe anemia
This case report and literature review describes a neonate with unexplained Coombs/DAT-negative severe hemolytic anemia, pulmonary hypertens…
A rare genetic variant in the KLF1 gene can cause severe anemia and lung issues in newborns, making early testing vital for accurate diagnos…
AI prescreening tool identifies primary aldosteronism with AUROC 0.709 in hypertension
AI tool helps identify patients with high blood pressure condition
In a retrospective cohort of 22,264 adults with hypertension or PA testing, an AI prescreening tool using EHR data achieved an AUROC of 0.70…
A new AI tool uses electronic health records to help doctors find patients who need testing for a specific heart condition.
Aquatic Exercise Therapy for Blood Pressure Management in Elderly Patients with Hypertension
Pool workouts may lower blood pressure in older adults
Aquatic exercise therapy significantly lowers systolic and diastolic blood pressure in elderly patients, offering a viable non-pharmacologic…
A new analysis finds aquatic exercise may cut systolic blood pressure by about 11 points in older adults with hypertension.
Mineralocorticoid receptor antagonists exert cardioprotective effects by restoring coronary microvascular function
Mineralocorticoid Receptor Antagonists May Improve Heart Function in Heart Failure
This mini-review examines the mechanisms of mineralocorticoid receptor antagonists in patients with heart failure, hypertension, and chronic…
New research highlights how mineralocorticoid receptor antagonists may protect the heart by improving blood flow in small vessels for patien…
One anastomosis gastric bypass provides durable weight loss and metabolic improvements over 15 years
Gastric Bypass Shows Durable Weight Loss and Health Improvements
This meta-analysis of 1729 patients evaluates the long-term outcomes of one anastomosis gastric bypass (OAGB). The analysis indicates durabl…
Gastric bypass surgery can lead to lasting weight loss and improved conditions like diabetes and high blood pressure over 15 years.
Selective aldosterone synthase inhibitors reduce systolic blood pressure by 7.9 mmHg in patients with CKD
Aldosterone Synthase Inhibitors May Lower Blood Pressure in CKD Patients
This meta-analysis of 1148 patients with CKD and uncontrolled hypertension found that selective aldosterone synthase inhibitors (ASIs) reduc…
New research suggests that aldosterone synthase inhibitors could help manage high blood pressure and kidney damage in patients with chronic …