How many clinical trials are tracked for Smallpox?

20 trials are tracked, 3 with published results.

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Smallpox

Part of Orthopoxvirus Infection

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Smallpox

20 trials tracked for Smallpox: 7 in phase 3 or 4 and 3 with published results. The most-cited published study has 413 citations.

20Trials tracked

7Phase 3 & 4

0Recruiting

3With published results

Phase distribution

Phase 4 2 Phase 3 5 Phase 2 12 Phase 1 1

Phase 3 A Trial to Assess the Safety, Tolerability, and Pharmacokinetics of the Anti-Orthopoxvirus Compound Tecovirimat Completed · 413 cited
Phase 3 A Trial to Evaluate Immunogenicity and Safety of Three Consecutive Production Lots of IMVAMUNE® (MVA-BN®) Smallpox Vaccine in Healthy, Vaccinia-naïve Subjects Completed · 66 cited
Phase 3 Freeze-Dried MVA-BN® Lot Consistency Smallpox Trial Completed · 18 cited
Phase 4 Safety, Tolerability and PK of TPOXX in Adults Weighing More Than 120 KG Completed
Phase 4 Drug-drug Interaction Study of TPOXX When Co-administered With Phosphate Binders Completed
Phase 3 Safety, Tolerability and Pharmacokinetics of TPOXX When Administered Orally for 28 Days Completed

Show 14 more trials

Phase 3 Safety and Efficacy of CJ-50300 in Healthy Volunteers Completed
Phase 2 A Phase II Trial to Compare a Liquid-frozen and a Freeze-dried Formulation of IMVAMUNE (MVA-BN®) Smallpox Vaccine in Vaccinia-naïve Healthy Subjects Completed
Phase 2 Dose Study of ACAM2000 Smallpox Vaccine in Previously Vaccinated Adults Completed
Phase 2 A Randomized, Double-blind, Placebo-controlled Study on Immunogenicity and Safety of MVA-BN (IMVAMUNE™) Smallpox Vaccine in Healthy Subjects Completed
Phase 2 ACAM 3000 MVA at Harvard Medical School Completed
Phase 2 Lyophilized IMVAMUNE® (1x10^8 TCID50) Versus Liquid IMVAMUNE® (1x10^8 TCID50) Administered Subcutaneously and a Lower Dose Liquid IMVAMUNE® (2x10^7 TCID50) Administered Intradermally Completed
Phase 2 Phase II Trial to Assess Safety and Immunogenicity of IMVAMUNE® Completed
Phase 2 An Open-Label Phase II Study to Evaluate Immunogenicity and Safety of a Single IMVAMUNE Booster Vaccination Two Years After the Last IMVAMUNE Vaccination in Former POX-MVA-005 Vaccinees Completed
Phase 2 Effect of Dose, Safety, Tolerability of a New Smallpox Vaccine in Adults Without Previous Smallpox Vaccination Completed
Phase 2 High Dose IMVAMUNE® in Vaccinia-Naive Individuals Completed
Phase 2 A Study to Evaluate Safety and Immunogenicity of One and Two Doses of IMVAMUNE® Smallpox Vaccine in 56-80 Year Old Vaccinia-experienced Subjects Completed
Phase 2 Randomized, Open-label Phase II Trial to Assess the Safety and Immunogenicity of MVA-BN Smallpox Vaccine in Immunocompromised Subjects With HIV Infection Completed
Phase 2 MVA Post-Event: Administration Timing and Boost Study Completed
Phase 1 Phase I Trial of an Investigational Small Pox Medication Completed

Showing the 20 most-cited and recently-updated of 20 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.