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Thyroid Neoplasm

Part of Head and Neck Cancer

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Thyroid Neoplasm

4 trials tracked for Thyroid Neoplasm: 1 in phase 3 or 4 and 1 with published results. The most-cited published study has 15 citations.

4Trials tracked
1Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 3 1 Phase 2 2 Other / NA 1
  1. Phase 3 Efficacy of Ropivacaine (With Epinephrine) in BABA Endoscopic and Robotic Thyroidectomy Completed · 15 cited
  2. Phase 2 A Phase II Trial of Valproic Acid in Patients With Advanced Thyroid Cancers of Follicular Cell Origin Completed
  3. Phase 2 Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors Completed
  4. N/A A Trial Comparing Wound Drainage and Post-operative Complications With and Without the Use of EVICEL™ Fibrin Sealant in Thyroidectomy Completed

Showing the 4 most-cited and recently-updated of 4 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Head and Neck Cancer

Related studies from across the Head and Neck Cancer family.

Contrast-enhanced ultrasound shows 81.6% diagnostic accuracy for differentiating benign from malignant thyroid nodules
Diabetes & Endocrinology Meta-analysis
Contrast-enhanced ultrasound shows 81.6% diagnostic accuracy for differentiating benign from malignant thyroid nodules Contrast-enhanced ultrasound shows promise for thyroid nodule diagnosis
This meta-analysis of 54 CEUS studies evaluated the diagnostic performance of contrast-enhanced ultrasound for characterizing thyroid nodule…
A new analysis finds contrast-enhanced ultrasound is 78.6% sensitive and 82.6% specific for telling benign from malignant thyroid nodules.
Case report and review: IVIg and efgartigimod in Guillain-Barré with Graves disease and thyroid cancer
Allergy & Immunology Sys. Review
Case report and review: IVIg and efgartigimod in Guillain-Barré with Graves disease and thyroid cancer Doctors treat a rare relapse of Guillain-Barré syndrome with new immune therapies
This case report and literature review describes a 33-year-old man with Guillain-Barré syndrome, Graves disease, and papillary thyroid carci…
A 33-year-old man with Guillain-Barré syndrome found relief after doctors treated his underlying thyroid cancer and used new immune therapie…
Review of 32 cases of thyroid hemiagenesis with carcinoma highlights surgical and diagnostic patterns
Diabetes & Endocrinology Sys. Review
Review of 32 cases of thyroid hemiagenesis with carcinoma highlights surgical and diagnostic patterns Doctors found rare thyroid cancer cases in patients with one missing half of their gland
This review and case series of 32 patients with thyroid hemiagenesis complicated by thyroid carcinoma synthesized diagnostic and treatment p…
A review of thirty-two patients shows that having half a thyroid gland does not stop cancer from forming. Most cases were treated with surge…
Machine learning model predicts central lymph node metastasis in papillary thyroid carcinoma
Diabetes & Endocrinology Cohort
Machine learning model predicts central lymph node metastasis in papillary thyroid carcinoma New AI tool predicts hidden cancer spread in early thyroid cases
This retrospective cohort study of 710 patients with clinically node-negative T1–T2 papillary thyroid carcinoma developed an interpretable m…
A smart new computer model can spot hidden cancer spread in early thyroid cases, helping surgeons decide exactly what to remove during opera…
TIRADS and Bethesda systems predict thyroid malignancy in 70 patients at Baghdad Teaching Hospital
Radiology & Imaging Cohort
TIRADS and Bethesda systems predict thyroid malignancy in 70 patients at Baghdad Teaching Hospital Family history and neck swelling signal higher risk of thyroid cancer
This prospective cross-sectional study evaluated 70 patients with thyroid complaints at Baghdad Teaching Hospital.
A new look at thyroid nodules shows that family history and neck swelling are key signs of cancer, helping doctors catch it sooner.
Case series describes four clear cell variant papillary thyroid carcinoma cases with NCOA4-RET fusions
Oncology Sys. Review
Case series describes four clear cell variant papillary thyroid carcinoma cases with NCOA4-RET fusions Rare Thyroid Cancer Has Unique Genetic Signature
This case series with literature review describes four pathologically confirmed cases of clear cell variant of papillary thyroid carcinoma d…
A rare thyroid cancer type may have a specific genetic cause that doctors can now look for.
Nomogram model using NLR, age, and ultrasound features discriminates papillary thyroid carcinoma from benign nodules
Oncology Cohort
Nomogram model using NLR, age, and ultrasound features discriminates papillary thyroid carcinoma from benign nodules New Tool Predicts Thyroid Cancer Without Surgery
This multicenter cohort study evaluated a nomogram model incorporating inflammatory biomarker NLR, patient age, and ultrasound features to d…
You wake up, brush your teeth, and notice a small lump in your neck.
Autopsy study finds 55% thyroid nodular disease prevalence in Mexico City hospital patients
Neurology Cohort
Autopsy study finds 55% thyroid nodular disease prevalence in Mexico City hospital patients Autopsy study finds high thyroid nodule rates in Mexico City, no link to salt iodination
A retrospective cohort study of 487 autopsies from a third-level hospital in Mexico City found a thyroid nodular disease prevalence of 55% a…
Autopsies in Mexico City reveal thyroid nodules are very common, yet changing salt iodination rules did not increase their rates.
Frozen visual encoders compared for thyroid nodule classification in the ThyroidEffi 1.0 dataset
Diabetes & Endocrinology Cohort
Frozen visual encoders compared for thyroid nodule classification in the ThyroidEffi 1.0 dataset Will AI Make Your Thyroid Biopsy Report More Trustworthy?
This cohort study evaluated frozen visual encoders, including MedSigLIP and ImageNet-pretrained models, on thyroid cytology cases with Bethe…
A new medical AI may not beat general AI on raw accuracy — but it knows when to hesitate, which matters more for the tricky thyroid biopsies…
Sedentary time, insomnia, and weight linked to high-risk thyroid nodules in retrospective cohort
Oncology Cohort
Sedentary time, insomnia, and weight linked to high-risk thyroid nodules in retrospective cohort Does sitting too much or poor sleep raise your risk for dangerous thyroid nodules?
A retrospective cohort study of 164 patients with thyroid nodules found that sedentary time >2 hours/day, insomnia, and elevated weight were…
Sitting too much, poor sleep, and higher weight raise the risk for dangerous thyroid nodules, while eating a diverse diet and smaller nodule…
BRAFV600E mutation testing shows diagnostic value in high-suspicion thyroid nodules with non-malignant cytology
Diabetes & Endocrinology Cohort
BRAFV600E mutation testing shows diagnostic value in high-suspicion thyroid nodules with non-malignant cytology When a thyroid nodule looks suspicious but tests say it's fine, what's the next step?
A prospective observational study of 562 ultrasound-high-suspicion thyroid nodules with non-malignant or indeterminate cytology found BRAFV6…
A positive genetic test for a specific mutation makes a suspicious thyroid nodule ten times more likely to be cancer, helping doctors decide…
Deep learning model using preoperative CT predicts lymph node metastasis in papillary thyroid carcinoma
Oncology Cohort
Deep learning model using preoperative CT predicts lymph node metastasis in papillary thyroid carcinoma Can a new AI model help thyroid cancer patients avoid unnecessary surgery?
A retrospective cohort study of 1560 PTC patients developed and validated ThyLNT, a Transformer-based 2.5D deep learning model using preoper…
A new AI model predicts lymph node spread in thyroid cancer better than standard scans, potentially sparing patients from unnecessary surger…