Research across Cancer
Related studies from across the Cancer family.
Completion thyroidectomy follows total thyroidectomy for similar operative safety in differentiated thyroid cancer
Less surgery may be safer for thyroid cancer patients
This meta-analysis of 43,362 patients evaluated the surgical safety of completion thyroidectomy (CT) compared to upfront total thyroidectomy…
For some thyroid cancers, a less extensive surgery may be safer with fewer complications.
Laryngeal obstruction as initial sign of MEN2B in two pediatric cases with RET mutations
Rare genetic disorder first shows as breathing trouble in children
This case report describes 2 pediatric patients with MEN2B presenting with laryngeal obstruction and progressive respiratory compromise as i…
Two children with a rare genetic condition first showed breathing trouble from nerve growths in the airway, not the usual symptoms.
TSH suppression therapy promotes tumor progression via G-protein signaling pathways in differentiated thyroid cancer
TSH Suppression Therapy Framework for Differentiated Thyroid Cancer
This systematic review synthesizes the biological mechanisms of TSH-mediated tumor progression and proposes a clinical decision-making frame…
New research outlines how TSH levels impact thyroid cancer growth and offers a new decision-making framework for personalized patient care.
I-SPECT/CT shows high patient-level specificity of 0.95 for detecting residual disease in DTC
Imaging technology shows promise for detecting thyroid cancer recurrence
This meta-analysis evaluates the diagnostic efficacy of I-SPECT/CT for identifying residual or recurrent disease in patients with differenti…
A new imaging method called I-SPECT/CT helps doctors find leftover or returning thyroid cancer cells with high accuracy after treatment.
Hemithyroidectomy is associated with a 3% higher risk difference in cancer recurrence rate
Hemithyroidectomy linked to higher thyroid cancer recurrence
This meta-analysis of 98,604 patients with differentiated thyroid carcinoma found that hemithyroidectomy (HT) was associated with a 3% highe…
A large meta-analysis found that hemithyroidectomy for differentiated thyroid cancer has a higher recurrence rate than total thyroidectomy, …
WBRT shows no significant survival benefit in thyroid cancer brain metastases meta-analysis
Whole-brain radiation shows no clear survival benefit for thyroid cancer brain metastases
A systematic review and individual patient data meta-analysis of 247 patients with thyroid cancer brain metastases found whole-brain radiati…
Whole-brain radiation therapy showed no clear survival benefit for patients with thyroid cancer that spread to their brain.
Nivolumab monotherapy yielded 12-month progression-free survival in metastatic anaplastic thyroid cancer
Off-label immunotherapy may help some patients with metastatic anaplastic thyroid cancer
This case report describes a 76-year-old female with metastatic anaplastic thyroid cancer treated with off-label nivolumab monotherapy. The …
A single case report suggests off-label nivolumab helped a 76-year-old woman live longer with metastatic anaplastic thyroid cancer.
Meta-analysis finds germline LTS and somatic TERT variants are mutually exclusive in thyroid cancer and melanoma
Two different cancer drivers do not appear together in these tumors
This meta-analysis of retrospective observational cohorts examined germline long-telomere syndrome variants and somatic TERT promoter altera…
A large review of nearly 2,000 adults with thyroid cancer or melanoma found that two specific genetic changes never occur in the same tumor.
Case report details multimodal treatment for aggressive thyroid carcinoma
First new treatment combination in six months stabilizes advanced thyroid cancer
A 61-year-old man with papillary thyroid carcinoma achieved disease stabilization after thyroidectomy, radiotherapy, and targeted therapy. T…
A 61-year-old man with advanced thyroid cancer saw his disease stop growing after a specific mix of treatments within six months of his diag…
Network meta-analysis reveals induction immunochemotherapy plus CCRT improves survival for unresectable esophageal cancer patients compared to CCRT alone
Immunotherapy combinations show promise for hard-to-treat esophageal cancer
A comprehensive network meta-analysis of 9,648 patients indicates that induction immunochemotherapy followed by concurrent chemoradiotherapy…
Adding immunotherapy to standard treatment may help people with advanced esophageal cancer live longer, according to a new analysis of many …
Ultrasound-guided salvage brachytherapy with interstitial hyperthermia shows low toxicity in locally recurrent prostate cancer
New prostate cancer treatment shows low side effects after 5 years
This prospective phase 2 trial evaluated ultrasound-guided salvage brachytherapy with interstitial hyperthermia in 109 patients with locally…
A new treatment for recurrent prostate cancer kept 93% of patients alive at 5 years with very low serious side effects.
Meta-analysis shows percutaneous irreversible electroporation plus immunotherapy improves outcomes in locally advanced pancreatic cancer
Adding immunotherapy to ablation therapy extends life for pancreatic cancer patients
This systematic review and meta-analysis evaluated percutaneous irreversible electroporation combined with immunotherapy versus irreversible…
Adding immune therapy to ablation therapy helps patients live longer with locally advanced pancreatic cancer without causing more side effec…