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Upper Urinary Tract Urothelial Carcinoma

Part of Cancer

1 published article · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Cancer

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Liquid biopsy guides kidney-sparing decisions in upper tract urothelial carcinoma without replacing standard care
Urology Sys. Review
Liquid biopsy guides kidney-sparing decisions in upper tract urothelial carcinoma without replacing standard care Liquid biopsy helps doctors decide on kidney-sparing care for upper tract urothelial carcinoma
This review discusses liquid biopsy-guided kidney-sparing management for patients with upper tract urothelial carcinoma. The authors note th…
A review shows liquid biopsy adds value to kidney-sparing decisions for upper tract urothelial carcinoma but does not replace standard imagi…
Metachronous non-muscle invasive bladder cancer after UTUC has worse recurrence and progression with BCG than primary disease
Urology Meta-analysis
Metachronous non-muscle invasive bladder cancer after UTUC has worse recurrence and progression with BCG than primary disease Doctors found that bladder cancer returning later has higher risk of coming back again
This systematic review and meta-analysis of 1292 patients found that metachronous non-muscle invasive bladder cancer after upper tract uroth…
A large review shows bladder cancer returning after a previous kidney cancer treatment is more likely to grow back. This group also has a lo…
Systematic review of preclinical CBD effects in canine cancers
Cardiology Meta-analysis
Systematic review of preclinical CBD effects in canine cancers Lab tests suggest CBD may help treat cancer in dogs
This is a systematic review of preclinical studies on cannabidiol for canine cancers. It synthesizes evidence of antiproliferative and proap…
Lab tests suggest CBD may help treat cancer in dogs by slowing growth and triggering cell death, though human use remains unproven.
FDA approves OPDIVO QVANTIG for multiple advanced cancer indications including renal cell carcinoma and melanoma
Oncology FDA Approval
FDA approves OPDIVO QVANTIG for multiple advanced cancer indications including renal cell carcinoma and melanoma FDA approves subcutaneous nivolumab combination for multiple advanced cancers
This FDA approval document grants authorization for OPDIVO QVANTIG, a subcutaneous combination of nivolumab and hyaluronidase, for specified…
The FDA has approved a new subcutaneous form of nivolumab for several advanced cancers, offering a more convenient treatment option for elig…
Early time-of-day immune checkpoint inhibitor administration improves overall survival in advanced solid tumors
Oncology Meta-analysis
Early time-of-day immune checkpoint inhibitor administration improves overall survival in advanced solid tumors Cancer Patients Live Longer When Immunotherapy Starts Early in Day
This systematic review and meta-analysis evaluated 6129 patients with advanced solid tumors receiving immune checkpoint inhibitors. Earlier …
• Morning immunotherapy shots link to longer survival for advanced cancers • Helps patients fighting lung stomach kidney and other tough can…
Systematic review and meta-analysis of disitamab vedotin efficacy in urothelial carcinoma
Urology Meta-analysis
Systematic review and meta-analysis of disitamab vedotin efficacy in urothelial carcinoma Researchers Find Disitamab Vedotin Shows Activity In Bladder Cancer
This systematic review and meta-analysis evaluates disitamab vedotin-based therapy in HER2-negative and HER2-low locally advanced or metasta…
A new review suggests the drug disitamab vedotin might work for some bladder cancer patients with low or negative HER2 levels.
Disitamab vedotin plus PD-1 inhibitor showed high response rates in urothelial carcinoma patients across six centers
Allergy & Immunology Cohort
Disitamab vedotin plus PD-1 inhibitor showed high response rates in urothelial carcinoma patients across six centers New Drug Combo Shows Strong Results for Advanced Bladder Cancer
This retrospective cohort study evaluated disitamab vedotin combined with a PD-1 inhibitor in 132 patients with locally advanced or metastat…
A new drug pairing shrank tumors in 71% of advanced bladder cancer patients, even those with diabetes or kidney problems.
Camrelizumab plus nab-paclitaxel showed modest activity in previously treated advanced urothelial carcinoma patients
Oncology Phase II
Camrelizumab plus nab-paclitaxel showed modest activity in previously treated advanced urothelial carcinoma patients New Treatment Extends Life for Bladder Cancer Patients
This multicenter Phase II study evaluated camrelizumab plus nab-paclitaxel in 60 patients with advanced urothelial carcinoma who progressed …
For years, Mark, 64, thought he’d beaten cancer.
Systematic review of extended versus standard pelvic lymph node dissection in bladder cancer surgery
Oncology Sys. Review
Systematic review of extended versus standard pelvic lymph node dissection in bladder cancer surgery More Lymph Nodes Removed, Better Survival — But at What Cost?
This systematic review analyzed 993 randomized participants undergoing radical cystectomy for muscle-invasive or treatment-refractory non-mu…
This surgery could help some live longer, but it’s not risk-free.
Magrolimab plus docetaxel shows limited efficacy in metastatic lung and urothelial cancers
Infectious Disease Cohort
Magrolimab plus docetaxel shows limited efficacy in metastatic lung and urothelial cancers New Drug Combo Fails to Shrink Tough Lung and Bladder Cancers
This cohort study evaluated magrolimab plus docetaxel in patients with metastatic non-small cell lung cancer, small cell lung cancer, and ur…
This study shows that adding a new drug to standard chemotherapy did not help patients with advanced lung or bladder cancer live longer or s…
Review: PD1/PDL1 spatial interactions predict pembrolizumab response in metastatic urothelial carcinoma
Oncology
Review: PD1/PDL1 spatial interactions predict pembrolizumab response in metastatic urothelial carcinoma New Scan Shows Exactly Which Immune Cells Fight Cancer
This review discusses a proof-of-concept study examining PD1/PDL1 spatial interactions in tumor samples from patients with metastatic urothe…
This new method lets doctors see exactly which immune cells are actually fighting the tumor, not just hanging out nearby.
Neoadjuvant atezolizumab shows spatial biomarker changes in operable urothelial carcinoma patients
Oncology Phase II
Neoadjuvant atezolizumab shows spatial biomarker changes in operable urothelial carcinoma patients How a Bladder Cancer Drug Remodels the Tumor Neighborhood
This single-arm, phase II trial evaluated neoadjuvant atezolizumab in patients with operable urothelial carcinoma.
A bladder cancer drug physically breaks down the walls blocking immune cells in tumors, helping doctors predict which patients will respond …