Mode
Home
Research
Clinical Trials Drug Pipeline Weekly Digests
Reference
Conditions Medications
Community
Questions
Text Size
Log in / Sign up
Home › Conditions › Uterine Fibroids

Uterine Fibroids

Subtypes of Uterine Fibroids

Diffuse uterine leiomyomatosis 1 Fibroids 1

7 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Uterine Fibroids

31 trials tracked for Uterine Fibroids: 14 in phase 3 or 4 and 9 with published results. The most-cited published study has 218 citations.

31Trials tracked
14Phase 3 & 4
0Recruiting
9With published results
Phase distribution
Phase 4 5 Phase 3 9 Phase 2 7 Phase 1 1 Other / NA 9
  1. Phase 3 PGL4001 Efficacy Assessment in Reduction of Symptoms Due to Uterine Leiomyomata Completed · 218 cited
  2. Phase 3 A Phase 3 Study to Evaluate the Efficacy and Safety of Relugolix (TAK-385) 40 mg Compared With Leuprorelin in the Treatment of Uterine Fibroids Completed · 94 cited
  3. Phase 3 A Placebo-Controlled, Phase 3 Study of Relugolix (TAK-385) 40 mg in the Treatment of Pain Symptoms Associated With Uterine Fibroids Completed · 77 cited
  4. Phase 3 An Extension Study to Evaluate the Efficacy and Safety of Elagolix in Premenopausal Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids Completed · 67 cited
  5. Phase 4 Efficacity Assessment of PREVADH® in Adhesion Prevention in Gynaecologic Surgery Completed · 26 cited
  6. Phase 3 Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids Completed · 22 cited
Show 25 more trials
  1. Phase 3 Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women Completed · 21 cited
  2. Phase 3 Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women (Replicate Study) Completed · 21 cited
  3. Phase 4 A Study to Evaluate the Safety and Efficacy of Elagolix for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women Completed · 3 cited
  4. Phase 4 Pilot of Letrozole for Uterine Myomas Completed
  5. Phase 4 Treatment of Heavy Menstrual Bleeding in Women With Uterine Fibroids Completed
  6. Phase 4 A Prospective Study Comparing Contour SE™ Microspheres to Embosphere® Microspheres for Treating Symptomatic Uterine Fibroids With Uterine Fibroid Embolization (UFE) Completed
  7. Phase 3 MR Guided Focused Ultrasound Treatment of Uterine Fibroids With Enhanced Sonication Completed
  8. Phase 3 Long-Term Safety Study of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women Completed
  9. Phase 2 Safety and Efficacy in Premenopausal Women With Heavy Menstrual Bleeding (HMB) Associated With Uterine Fibroids (UF) Completed
  10. Phase 2 Safety and Efficacy of Telapristone Acetate (Proellex®) Administered Vaginally for the Treatment of Uterine Fibroids Completed
  11. Phase 2 Safety and Efficacy of Elagolix in Pre-Menopausal Women With Heavy Uterine Bleeding and Uterine Fibroids Completed
  12. Phase 2 Pilot Study of MRI-Guided High Intensity Focused Ultrasound Ablation of Uterine Fibroids Completed
  13. Phase 2 Extension Study of Proellex in Women Who Have Previously Completed Study ZPU 003 Completed
  14. Phase 2 A Multi-Center, Parallel Design, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of 6 and 12 mg Proellex® (Telapristone Acetate) Administered Orally in the Treatment of Premenopausal Women With Confirmed Symptomatic Uterine Fibroids Completed
  15. Phase 2 Evaluation of Safety, Pharmacokinetics, and Efficacy of Proellex Administered Vaginally in Women With Uterine Fibroids Completed
  16. Phase 1 Pharmacokinetics and Hepatic Safety of EGCG Completed
  17. N/A MyoSure Hysteroscopic Tissue Removal System Registry Study Completed
  18. N/A Evaluation of Uterine Patency Following Sonography-guided Transcervical Ablation of Fibroids Completed
  19. N/A ExAblate UF V2 System for the Treatment of Symptomatic Uterine Fibroids Completed
  20. N/A Laparoscopic Radiofrequency Ablation (RFA) of Symptomatic Uterine Fibroids Completed
  21. N/A Therapeutic Magnetic Resonance Imaging (MRI)-Guided High Intensity Focused Ultrasound (HIFU) Ablation of Uterine Fibroids Completed
  22. N/A Does 3D Laparoscopy Improve Vaginal Cuff Suture Time? Completed
  23. N/A Hysteroscopic Cryomyolysis for the Treatment of Submucosal Leiomyomata Completed
  24. N/A Safety Study of ExAblate for the Treatment of Uterine Fibroids Completed
  25. N/A HOME Study: Hysteroscopic Office Myomectomy Evaluation Completed

Showing the 31 most-cited and recently-updated of 31 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Meta-analysis identifies preoperative tumor size and count as key predictors for recurrence following laparoscopic myomectomy in women
OB/GYN & Women's Health Meta-analysis
Meta-analysis identifies preoperative tumor size and count as key predictors for recurrence following laparoscopic myomectomy in women Large fibroids and many fibroids raise recurrence risk after myomectomy surgery
A meta-analysis of 2160 patients reveals that large uterine fibroids and multiple tumors significantly increase recurrence risk after laparo…
A meta-analysis of 2160 patients shows that large preoperative fibroids and multiple fibroids significantly increase the risk of recurrence …
Jun 1, 2026
Myomectomy for intramural fibroids improves pregnancy chances in women undergoing IVF
OB/GYN & Women's Health Meta-analysis
Myomectomy for intramural fibroids improves pregnancy chances in women undergoing IVF Women with fibroids had better pregnancy chances after myomectomy before IVF treatment
This systematic review evaluated women with intramural uterine fibroids undergoing IVF or ICSI cycles. Researchers found a substantially hig…
A large review found that removing fibroids before IVF helped women get pregnant more often. This study looked at many patients to see if su…
Jun 1, 2026
Residence in mining districts associated with higher hospitalization rates for uterine and ovarian pathologies among gynecological inpatients
OB/GYN & Women's Health Cohort
Residence in mining districts associated with higher hospitalization rates for uterine and ovarian pathologies among gynecological inpatients Mining Towns See More Gynecology Visits
This retrospective cross-sectional study examined 4,935 gynecological inpatients at a tertiary hospital in Heilongjiang Province, China.
Women in China's mining towns face higher rates of gynecological issues like fibroids and polyps, with hospitalization rates nearly five tim…
Frontiers Apr 20, 2026
GWAS meta-analysis identifies genetic risk loci for female genital tract polyps in women
Genetics & Precision Medicine Meta-analysis
GWAS meta-analysis identifies genetic risk loci for female genital tract polyps in women New DNA clues link common gynecological issues to endometriosis and cancer risks
This GWAS meta-analysis examined 48,400 cases and 477,134 controls across four biobanks to identify risk loci for female genital tract polyp…
A massive DNA study of nearly half a million women reveals genetic links between common gynecological polyps, endometriosis, fibroids, and e…
medRxiv Apr 18, 2026
Two-stage hysteroscopic myomectomy in diffuse uterine leiomyomatosis led to natural conception and full-term delivery in a 29-year-old nulliparous woman
Rheumatology Sys. Review
Two-stage hysteroscopic myomectomy in diffuse uterine leiomyomatosis led to natural conception and full-term delivery in a 29-year-old nulliparous woman A Rare Womb Condition Didn't Stop This Mom's Pregnancy
This case report and literature review describes a 29-year-old nulliparous woman with diffuse uterine leiomyomatosis who underwent two-stage…
After two careful surgeries to clear countless small fibroids from her womb, a 29-year-old conceived on her own and delivered a healthy baby…
Frontiers Apr 13, 2026
Huayu Xiaozheng Decoction added to triptorelin and mifepristone for uterine fibroids in 102 women
OB/GYN & Women's Health RCT
Huayu Xiaozheng Decoction added to triptorelin and mifepristone for uterine fibroids in 102 women A New Fibroid Treatment Combo Shows Promise—With Fewer Side Effects
A randomized controlled trial in 102 women with uterine fibroids compared triptorelin plus mifepristone with or without Huayu Xiaozheng Deco…
Adding a traditional Chinese herbal formula to standard fibroid drugs improved results and lowered side effects for women seeking relief.
Apr 9, 2026
Machine learning models show predictive potential for uterine fibroid treatment outcomes in meta-analysis
OB/GYN & Women's Health Meta-analysis
Machine learning models show predictive potential for uterine fibroid treatment outcomes in meta-analysis Can AI predict if fibroid treatments will work for you?
A systematic review and meta-analysis of 14 studies in women with uterine fibroids found machine learning models, particularly combined radi…
A new analysis suggests machine learning could one day predict if fibroid treatments will work for you, though the technology isn't ready fo…
Apr 2, 2026

Questions about Uterine Fibroids

Can machine learning models predict my treatment outcome for uterine fibroids?

Yes, machine learning models show promise for predicting uterine fibroid treatment outcomes, especially for HIFU ablation, but they are not yet ready for routine clinical use.

Full answer →
Does living in a mining district increase my risk of hospitalization for uterine fibroids?

Yes, living in a mining district is linked to higher hospitalization rates for uterine fibroids, according to a study from China's northeastern mining region.

Full answer →