Research across Cancer
Related studies from across the Cancer family.
Follicular T cell subsets and tertiary lymphoid structures may guide immunotherapy in ovarian cancer
New immune targets offer hope for ovarian cancer patients
This narrative review synthesizes evidence on follicular T cell subsets, tertiary lymphoid structures, and other immune features in ovarian …
A review highlights new immune system features that could help doctors predict treatment success and find better ways to fight ovarian cance…
Case report of YL205 antibody-drug conjugate in platinum-resistant ovarian carcinoma
First patient achieves complete response with new ovarian cancer drug YL205
This is a single-patient case report of a 40-year-old woman with platinum-resistant, BRCA-wildtype high-grade serous ovarian carcinoma treat…
A single patient with advanced ovarian cancer achieved a complete response after 24 weeks of treatment with YL205, a new antibody-drug conju…
Review of gynecologic malignancies highlights dormant tumor cells as a therapeutic target
Doctors find dormant cancer cells could help stop gynecologic cancer from coming back after treatment
This narrative review examines ovarian, cervical, endometrial, and uterine sarcoma cancers. The authors synthesize evidence regarding dorman…
A review shows that sleeping cancer cells might cause tumors to return. Targeting these hidden cells could help prevent recurrence in ovaria…
Narrative review discusses HPV-associated head and neck and cervical squamous cell carcinoma without reporting specific outcomes
Doctors Find Hidden Pattern in HPV Cancers That Changes Treatment
This narrative review addresses patients with HPV-associated tumors involving head and neck squamous cell carcinoma and squamous cell carcin…
HPV cancers in the head and neck hide from the immune system differently than cervical cancers, explaining why some patients respond better …
Conference report on AI ensemble for histopathological classification of ovarian carcinoma subtypes
AI Can Now Tell Apart Two Ovarian Cancers That Look Nearly Identical
This conference report describes a preclinical computational study using an attention-guided CNN ensemble to classify high-grade versus low-…
This technology could prevent misdiagnosis and ensure patients get the most effective treatment for their specific cancer type from day one.
Case report details long-term survival in appendiceal signet-ring cell carcinoma with uterine involvement
A rare cancer found in the uterus and ovaries may be treated with surgery and chemo for over five years
This case report describes a 45-year-old woman with signet-ring cell carcinoma of the appendix involving the uterus and ovaries.
A rare cancer starting in the appendix showed up in the uterus and ovaries. Treatment with surgery and drugs helped a woman survive past fiv…
Separate molecular profiling of mixed endometrial carcinoma components yields limited prognostic data in a small retrospective cohort
Separate tumor profiling may reveal hidden risks in mixed endometrial cancer
This hypothesis-generating retrospective cohort analysis included 8 patients with mixed endometrial carcinomas (MEEC).
In mixed endometrial cancer, testing each tumor component separately could uncover risk profiles that standard testing misses.
Residual disease after surgery linked to survival in low-grade serous ovarian cancer
For This Ovarian Cancer, Surgery Is Everything—Chemo May Not Help
This observational retrospective study of 25 patients with low-grade serous ovarian cancer found that residual disease status after primary …
For a rare ovarian cancer, a new study suggests that the quality of surgery is the single most important factor for survival, challenging th…
STAT1 and IL-7 show diagnostic potential for ovarian carcinoma subtypes in cohort study
Two Tiny Signals Could Help Doctors Tell Apart Two Ovarian Cancers
A cohort study analyzed transcriptome data from 68 patients with high-grade and low-grade serous ovarian carcinoma.
Two tiny gene signals may help doctors distinguish between two ovarian cancer types when biopsy results are unclear, guiding the right treat…
Chemotherapy in HGSOC patients modulates NK cell receptors and ligands, observational study finds
Chemotherapy linked to immune system changes in ovarian cancer patients
An observational cohort study of 107 HGSOC patients and 50 healthy controls found chemotherapy was associated with modulation of NK cell rec…
Chemotherapy in ovarian cancer may restore natural killer cell markers to healthy levels and boost proteins that help immune cells fight tum…