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Home › Conditions › Wilson Disease

Wilson Disease

Part of Movement Disorders

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Wilson Disease

9 trials tracked for Wilson Disease: 1 in phase 3 or 4 and 1 with published results. The most-cited published study has 72 citations.

9Trials tracked
1Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 3 1 Phase 2 3 Phase 1 3 Other / NA 2
  1. Phase 3 Trientine Tetrahydrochloride (TETA 4HCL) for the Treatment of Wilson's Disease Completed · 72 cited
  2. Phase 2 Copper Concentration & Histopathologic Changes in Liver Biopsy in Participants With Wilson Disease Treated With ALXN1840 Completed
  3. Phase 2 Copper and Molybdenum Balance in Participants With Wilson Disease Treated With ALXN1840 Completed
  4. Phase 2 Efficacy and Safety Study of WTX101 (ALXN1840) in Adult Wilson Disease Patients Completed
  5. Phase 1 Pharmacokinetic Study of Oral ALXN1840 in Japanese and Non-Japanese Adult Healthy Participants Completed
  6. Phase 1 Study of ALXN1840 on the Metabolism of a CYP2B6 Substrate in Healthy Participants Completed
Show 3 more trials
  1. Phase 1 Phase 1 Study of ALXN1840 on the Metabolism of a CYP2C9 Substrate in Healthy Participants. Completed
  2. N/A Single Daily Dosage of Trientine for Maintenance Treatment for Wilson Disease Completed
  3. N/A The Assessment of Copper Parameters in Wilson Disease Participants on Standard of Care Treatment Completed

Showing the 9 most-cited and recently-updated of 9 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
NODDI MRI shows phenotype-specific white matter alterations in Wilson disease patients
Neurology
NODDI MRI shows phenotype-specific white matter alterations in Wilson disease patients What does Wilson disease do to the brain's wiring? A new scan shows specific damage
An observational study of 30 Wilson disease patients and 30 matched controls found phenotype-specific microstructural white matter alteratio…
A new brain scan reveals specific wiring damage in Wilson disease patients, linking reduced nerve fiber density directly to slower processin…
medRxiv Apr 5, 2026

Research across Movement Disorders

Related studies from across the Movement Disorders family.

Quantitative susceptibility mapping shows higher deep gray matter alterations in Wilson's disease compared to healthy controls
Gastroenterology Meta-analysis
Quantitative susceptibility mapping shows higher deep gray matter alterations in Wilson's disease compared to healthy controls New scan findings show brain changes in Wilson's disease patients compared to healthy people
This meta-analysis evaluated quantitative susceptibility mapping (QSM) alterations in deep gray matter among 325 patients with Wilson's dise…
A new scan technique reveals specific brain changes in Wilson's disease patients, showing higher metal buildup in key areas compared to heal…
Apr 14, 2026