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Home › Medications › aripiprazole

aripiprazole

6 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of aripiprazole

74 trials tracked of aripiprazole: 58 in phase 3 or 4 and 13 with published results. The most-cited published study has 168 citations.

74Trials tracked
58Phase 3 & 4
0Recruiting
13With published results
Phase distribution
Phase 4 22 Phase 3 36 Phase 2 10 Phase 1 2 Other / NA 4
  1. Phase 3 Safety and Efficacy of Cariprazine in Patients With Schizophrenia Completed · 168 cited
  2. Phase 4 Comparison of Aripiprazole and Risperidone for the Treatment of People With First-Episode Psychosis Completed · 111 cited
  3. Phase 4 Metabolic Effects of Antipsychotics in Children Completed · 77 cited
  4. Phase 4 Preventing Relapse in Schizophrenia: Oral Antipsychotics Compared To Injectables: Evaluating Efficacy Completed · 72 cited
  5. Phase 4 Biomarkers in Autism of Aripiprazole and Risperidone Treatment (BAART) Completed · 54 cited
  6. Phase 3 Evaluating the Effectiveness of Aripiprazole and D-Cycloserine to Treat Symptoms Associated With Autism Completed · 45 cited
Show 44 more trials
  1. Phase 3 A Short Treatment Study of Aripiprazole in Pediatric Patients With Autistic Disorder Completed · 45 cited
  2. Phase 3 A Long-term, Extended Treatment Study of Aripiprazole in Pediatric Patients With Autistic Disorder Completed · 32 cited
  3. Phase 3 Open-label Study to Evaluate the Effectiveness of an Intramuscular Formulation of Aripiprazole (OPC-14597) as Maintenance Treatment in Patients With Bipolar I Disorder Completed · 19 cited
  4. Phase 4 A Trial to Explore Acceptance and Performance of Using a Digital Medicine System With Healthcare Professionals and Adults With Schizophrenia, Schizoaffective Disorder, or First Episode Psychosis on an Oral Atypical Antipsychotic Completed · 17 cited
  5. Phase 3 A Study to Compare Disease Progression and Modification Following Treatment With Paliperidone Palmitate Long-Acting Injection or Oral Antipsychotics in Participant's With Recent-onset Schizophrenia or Schizophreniform Completed · 14 cited
  6. Phase 3 Trial to Evaluate the Short-term Safety & Efficacy of Brexpiprazole Monotherapy in the Treatment of Adolescents With Schizophrenia Completed · 12 cited
  7. Phase 4 Trial of Aripiprazole in the Treatment of CD in Adolescents Completed · 9 cited
  8. Phase 4 Examining the Effects of Antipsychotic Medications on Insulin Sensitivity Completed
  9. Phase 4 Abilify as an Adjunctive Treatment for Refractory Depression Completed
  10. Phase 4 Effectiveness of Atypical Antipsychotic Medication for Outpatients With Anorexia Nervosa Completed
  11. Phase 4 15 Month Study for Adults Who Have Been Diagnosed With Schizophrenia and Incarcerated Completed
  12. Phase 4 Comparison of Optimal Antipsychotic Treatments for Adults With Schizophrenia Completed
  13. Phase 4 Phase IV Long-term Maintenance Study of Aripiprazole in the Treatment of Irritability Associated With Autistic Disorder Completed
  14. Phase 4 Open Label Drug Interaction Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) 100mg On The Pharmacokinetics Of Aripiprazole When Coadministered To Healthy Subjects Completed
  15. Phase 4 Study of Aripiprazole in Patients With Schizophrenia- Effects on Glucose Metabolism- Completed
  16. Phase 4 FMRI Brain Activation of Aripiprazole Treatment in Autism Spectrum Disorders Completed
  17. Phase 4 Comparison of Antipsychotics for Metabolic Problems in Schizophrenia or Schizoaffective Disorder Completed
  18. Phase 4 Aripiprazole Augmentation of SSRI Therapy in Treatment Refractory Depression Completed
  19. Phase 4 12- Week Open Label Treatment of Refractory Bipolar Depression Completed
  20. Phase 4 A Placebo-Controlled, Cross-Over Trial of Aripiprazole Completed
  21. Phase 4 Open Label Trial of Aripiprazole in Children and Adolescents With Tourette's Disorder Completed
  22. Phase 4 Effectiveness of Aripiprazole for Improving Side Effects of Clozapine in the Treatment of People With Schizophrenia Completed
  23. Phase 4 Switching Medication to Treat Schizophrenia Completed
  24. Phase 3 A Long-term, Extended Treatment Study of Aripiprazole in Pediatric Patients With Schizophrenia Completed
  25. Phase 3 Aripiprazole Effects on Alcohol Drinking and Craving Completed
  26. Phase 3 An Open-Label, Multicenter, Rollover, Long-term Study of Aripiprazole Intramuscular Depot in Participants With Schizophrenia Completed
  27. Phase 3 Safety and Tolerability Study of Once-weekly Oral Aripiprazole in Children and Adolescents With Tourette's Disorder Completed
  28. Phase 3 Efficacy & Safety Study of Once-weekly Oral Aripiprazole in Children and Adolescents With Tourette's Disorder Completed
  29. Phase 3 Efficacy & Safety Study of Once-weekly Oral Aripiprazole in Children and Adolescents With Tourette's Disorder (TD) Completed
  30. Phase 3 Aripiprazole for Bipolar Disorder and Alcohol Use Disorder Completed
  31. Phase 3 Study of Aripiprazole (Abilify) Versus Placebo in Children With Subsyndromal Bipolar Disorder Completed
  32. Phase 3 Study of Aripiprazole (Abilify) in Children With Symptoms of Mania Completed
  33. Phase 3 Oral Aripiprazole Open-Label Rollover Study Completed
  34. Phase 3 Aripiprazole in Children and Adolescents With Chronic Tic Disorder or Tourette's Disorder Completed
  35. Phase 3 Study of Aripiprazole in the Treatment of Children and Adolescents With Autistic Disorder (AD) Completed
  36. Phase 3 Study Evaluating the Safety and Efficacy of Fixed-dose Once-daily Oral Aripiprazole in Children and Adolescents With Tourette's Disorder Completed
  37. Phase 3 Efficacy & Safety Study of Oral Aripiprazole in Adolescents With Schizophrenia Completed
  38. Phase 3 The Combination of Aripiprazole and Antidepressants in Psychotic Major Depression Completed
  39. Phase 3 A Study of Relapse Prevention and the Effectiveness of Long-acting Injectable Risperidone and Quetiapine Tablets in the Treatment of Patients With Schizophrenia or Schizoaffective Disorder Completed
  40. Phase 3 Brexpiprazole (OPC-34712) Trial in the Treatment of Adults With Acute Schizophrenia Completed
  41. Phase 3 Aripiprazole in Children and Adolescents With Bipolar I Disorder Completed
  42. Phase 3 A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group-comparison Trial of Aripiprazole in the Treatment of Patients With Bipolar Disorder Experiencing a Manic or Mixed Episode Completed
  43. Phase 3 An Efficacy and Safety Study of Extended-Release (ER) Paliperidone in Adolescent Participants With Schizophrenia Completed
  44. Phase 3 Study of Aripiprazole in the Treatment of Serious Behavioral Problems in Children and Adolescents With Autistic Disorder (AD) Completed

Showing the 50 most-cited and recently-updated of 74 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Network meta-analysis compares risperidone and aripiprazole for autism irritability
Drug Pipeline Meta-analysis
Network meta-analysis compares risperidone and aripiprazole for autism irritability Risperidone and Aripiprazole Help Autistic Behaviors But Carry Risks
This network meta-analysis of randomized trials synthesized evidence on antipsychotics for autism spectrum disorder. Combined risperidone an…
Two antipsychotic drugs help reduce irritability in autistic people, but they also raise the risk of side effects compared to placebo.
medRxiv May 14, 2026
Cariprazine showed modest weight reduction versus aripiprazole in schizophrenia patients previously treated with olanzapine
Psychiatry RCT
Cariprazine showed modest weight reduction versus aripiprazole in schizophrenia patients previously treated with olanzapine Cariprazine shows modest weight benefit over aripiprazole in schizophrenia patients
This trial compared cariprazine to aripiprazole in patients with schizophrenia who had previously used olanzapine.
A trial found cariprazine linked to slightly more weight loss than aripiprazole in people with schizophrenia, though overall differences wer…
May 1, 2026
Case report review suggests LAI paliperidone stabilizes behavior in a 9-year-old with TBI over two years
Psychiatry Sys. Review
Case report review suggests LAI paliperidone stabilizes behavior in a 9-year-old with TBI over two years Long-acting shots help a boy control severe brain injury rage
This case report review describes a 9-year-old boy with severe traumatic brain injury and posttraumatic confusional state treated with long-…
A boy with severe brain injury rage found calm after months of failed pills, showing long-acting shots could help when daily medicine fails
Frontiers Apr 29, 2026
Immuno-kynurenine shifts track cognitive change in antipsychotic-naive first-episode schizophrenia
Psychiatry Guideline
Immuno-kynurenine shifts track cognitive change in antipsychotic-naive first-episode schizophrenia New Brain Signals Show Why Early Treatment Works
A longitudinal observational study of antipsychotic-naive first-episode schizophrenia patients and healthy controls examined peripheral infl…
Early treatment for schizophrenia clears thinking fog by fixing brain chemistry and immune signals that cause mental confusion before scary …
Frontiers Apr 15, 2026
Aripiprazole linked to less insight improvement than dopamine antagonists in schizophrenia trial
Psychiatry RCT
Aripiprazole linked to less insight improvement than dopamine antagonists in schizophrenia trial Can reducing symptoms help people with schizophrenia gain insight into their illness?
A 6-week RCT of 144 schizophrenia spectrum disorder patients found symptom reduction was associated with improved clinical insight.
Reducing symptoms helps people with schizophrenia gain insight into their illness, but early improvement in hallucinations and delusions mat…
Apr 7, 2026
Planned trial compares injectable antipsychotics to usual care for psychosis with stimulant use
Psychiatry Phase III
Planned trial compares injectable antipsychotics to usual care for psychosis with stimulant use Hong Kong trial planned to test antipsychotic injections for substance use with psychosis
A trial record describes a planned phase 2/3 study of 165 individuals in Hong Kong with substance use disorders and psychosis.
Hong Kong researchers plan a trial to test long-acting antipsychotic injections for people with substance use disorders and psychosis.
CT.gov Apr 3, 2026