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Patient Mode — summaries use plain language, avoiding clinical jargon.
Psychiatry
RCT
Cariprazine showed modest weight reduction versus aripiprazole in schizophrenia patients previously treated with olanzapine.
Cariprazine shows modest weight benefit over aripiprazole in schizophrenia patients
This trial compared cariprazine to aripiprazole in patients with schizophrenia who had previously used olanzapine. While both groups improve…
A trial found cariprazine linked to slightly more weight loss than aripiprazole in people with schizophrenia, though overall differences wer…
May 1, 2026
Psychiatry
Sys. Review
Case report review suggests LAI paliperidone stabilizes behavior in a 9-year-old with TBI over two years
Long-acting shots help a boy control severe brain injury rage
This case report review describes a 9-year-old boy with severe traumatic brain injury and posttraumatic confusional state treated with long-…
A boy with severe brain injury rage found calm after months of failed pills, showing long-acting shots could help when daily medicine fails
Frontiers
Apr 29, 2026
Psychiatry
Guideline
Immuno-kynurenine shifts track cognitive change in antipsychotic-naive first-episode schizophrenia
New Brain Signals Show Why Early Treatment Works
A longitudinal observational study of antipsychotic-naive first-episode schizophrenia patients and healthy controls examined peripheral infl…
Early treatment for schizophrenia clears thinking fog by fixing brain chemistry and immune signals that cause mental confusion before scary …
Frontiers
Apr 15, 2026
Psychiatry
RCT
Aripiprazole linked to less insight improvement than dopamine antagonists in schizophrenia trial
Can reducing symptoms help people with schizophrenia gain insight into their illness?
A 6-week RCT of 144 schizophrenia spectrum disorder patients found symptom reduction was associated with improved clinical insight. Patients…
Reducing symptoms helps people with schizophrenia gain insight into their illness, but early improvement in hallucinations and delusions mat…
Apr 7, 2026
Psychiatry
Phase III
Planned trial compares injectable antipsychotics to usual care for psychosis with stimulant use
Hong Kong trial planned to test antipsychotic injections for substance use with psychosis
A trial record describes a planned phase 2/3 study of 165 individuals in Hong Kong with substance use disorders and psychosis. The study wil…
Hong Kong researchers plan a trial to test long-acting antipsychotic injections for people with substance use disorders and psychosis.
CT.gov
Apr 3, 2026